Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 10

1.

A RADAR-Based Assay to Isolate Covalent DNA Complexes in Bacteria.

Aldred KJ, Payne A, Voegerl O.

Antibiotics (Basel). 2019 Feb 27;8(1). pii: E17. doi: 10.3390/antibiotics8010017.

2.

Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase.

Aldred KJ, Blower TR, Kerns RJ, Berger JM, Osheroff N.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):E839-46. doi: 10.1073/pnas.1525055113. Epub 2016 Jan 20.

3.

Activity of quinolone CP-115,955 against bacterial and human type II topoisomerases is mediated by different interactions.

Aldred KJ, Schwanz HA, Li G, Williamson BH, McPherson SA, Turnbough CL Jr, Kerns RJ, Osheroff N.

Biochemistry. 2015 Feb 10;54(5):1278-86. doi: 10.1021/bi501073v. Epub 2015 Jan 23.

4.

Bacillus anthracis GrlAV96A topoisomerase IV, a quinolone resistance mutation that does not affect the water-metal ion bridge.

Aldred KJ, Breland EJ, McPherson SA, Turnbough CL Jr, Kerns RJ, Osheroff N.

Antimicrob Agents Chemother. 2014 Dec;58(12):7182-7. doi: 10.1128/AAC.03734-14. Epub 2014 Sep 22.

5.

Role of the water-metal ion bridge in mediating interactions between quinolones and Escherichia coli topoisomerase IV.

Aldred KJ, Breland EJ, Vlčková V, Strub MP, Neuman KC, Kerns RJ, Osheroff N.

Biochemistry. 2014 Sep 2;53(34):5558-67. doi: 10.1021/bi500682e. Epub 2014 Aug 21.

6.

Mechanism of quinolone action and resistance.

Aldred KJ, Kerns RJ, Osheroff N.

Biochemistry. 2014 Mar 18;53(10):1565-74. doi: 10.1021/bi5000564. Epub 2014 Mar 7. Review.

7.

Overcoming target-mediated quinolone resistance in topoisomerase IV by introducing metal-ion-independent drug-enzyme interactions.

Aldred KJ, Schwanz HA, Li G, McPherson SA, Turnbough CL Jr, Kerns RJ, Osheroff N.

ACS Chem Biol. 2013 Dec 20;8(12):2660-8. doi: 10.1021/cb400592n. Epub 2013 Sep 30.

8.

Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance.

Aldred KJ, McPherson SA, Turnbough CL Jr, Kerns RJ, Osheroff N.

Nucleic Acids Res. 2013 Apr;41(8):4628-39. doi: 10.1093/nar/gkt124. Epub 2013 Mar 4.

9.

Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance.

Aldred KJ, McPherson SA, Wang P, Kerns RJ, Graves DE, Turnbough CL Jr, Osheroff N.

Biochemistry. 2012 Jan 10;51(1):370-81. doi: 10.1021/bi2013905. Epub 2011 Dec 16.

10.

Mitochondrial genome sequence of Unionicola foili (Acari: Unionicolidae): a unique gene order with implications for phylogenetic inference.

Ernsting BR, Edwards DD, Aldred KJ, Fites JS, Neff CR.

Exp Appl Acarol. 2009 Dec;49(4):305-16. doi: 10.1007/s10493-009-9263-1. Epub 2009 Apr 8.

PMID:
19353278

Supplemental Content

Loading ...
Support Center