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Items: 1 to 20 of 58

1.

Blood Neutrophils In COPD But Not Asthma Exhibit A Primed Phenotype With Downregulated CD62L Expression.

Lokwani R, Wark PA, Baines KJ, Fricker M, Barker D, Simpson JL.

Int J Chron Obstruct Pulmon Dis. 2019 Nov 15;14:2517-2525. doi: 10.2147/COPD.S222486. eCollection 2019.

2.

Sputum transcriptomics implicates increased p38 signalling activity in severe asthma.

Baines KJ, Fricker M, McDonald VM, Simpson JL, Wood LG, Wark PAB, Macdonald HE, Reid A, Gibson PG.

Respirology. 2019 Dec 6. doi: 10.1111/resp.13749. [Epub ahead of print]

PMID:
31808595
3.

Targeting Treatable Traits in Severe Asthma: A Randomised Controlled Trial.

McDonald VM, Clark VL, Cordova-Rivera L, Wark PAB, Baines KJ, Gibson PG.

Eur Respir J. 2019 Dec 5. pii: 1901509. doi: 10.1183/13993003.01509-2019. [Epub ahead of print]

PMID:
31806719
4.

Soluble fibre supplementation with and without a probiotic in adults with asthma: A 7-day randomised, double blind, three way cross-over trial.

McLoughlin R, Berthon BS, Rogers GB, Baines KJ, Leong LEX, Gibson PG, Williams EJ, Wood LG.

EBioMedicine. 2019 Aug;46:473-485. doi: 10.1016/j.ebiom.2019.07.048. Epub 2019 Jul 31.

5.

The Emerging Role of Neutrophil Extracellular Traps in Respiratory Disease.

Twaddell SH, Baines KJ, Grainge C, Gibson PG.

Chest. 2019 Oct;156(4):774-782. doi: 10.1016/j.chest.2019.06.012. Epub 2019 Jun 29. Review.

PMID:
31265835
6.

Dysregulation of sputum columnar epithelial cells and products in distinct asthma phenotypes.

Qin L, Gibson PG, Simpson JL, Baines KJ, McDonald VM, Wood LG, Powell H, Fricker M.

Clin Exp Allergy. 2019 Nov;49(11):1418-1428. doi: 10.1111/cea.13452. Epub 2019 Aug 6.

PMID:
31264263
7.

Hypersegmented airway neutrophils and its association with reduced lung function in adults with obstructive airway disease: an exploratory study.

Lokwani R, Wark PAB, Baines KJ, Barker D, Simpson JL.

BMJ Open. 2019 Jan 28;9(1):e024330. doi: 10.1136/bmjopen-2018-024330.

8.

A sputum 6-gene signature predicts future exacerbations of poorly controlled asthma.

Fricker M, Gibson PG, Powell H, Simpson JL, Yang IA, Upham JW, Reynolds PN, Hodge S, James AL, Jenkins C, Peters MJ, Marks GB, Baraket M, Baines KJ.

J Allergy Clin Immunol. 2019 Jul;144(1):51-60.e11. doi: 10.1016/j.jaci.2018.12.1020. Epub 2019 Jan 22.

PMID:
30682452
9.

Galectin-3 enhances monocyte-derived macrophage efferocytosis of apoptotic granulocytes in asthma.

Erriah M, Pabreja K, Fricker M, Baines KJ, Donnelly LE, Bylund J, Karlsson A, Simpson JL.

Respir Res. 2019 Jan 3;20(1):1. doi: 10.1186/s12931-018-0967-9.

10.

Azithromycin treatment modifies airway and blood gene expression networks in neutrophilic COPD.

Baines KJ, Wright TK, Gibson PG, Powell H, Hansbro PM, Simpson JL.

ERJ Open Res. 2018 Nov 5;4(4). pii: 00031-2018. doi: 10.1183/23120541.00031-2018. eCollection 2018 Oct.

11.

Saturated fatty acids, obesity, and the nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in asthmatic patients.

Wood LG, Li Q, Scott HA, Rutting S, Berthon BS, Gibson PG, Hansbro PM, Williams E, Horvat J, Simpson JL, Young P, Oliver BG, Baines KJ.

J Allergy Clin Immunol. 2019 Jan;143(1):305-315. doi: 10.1016/j.jaci.2018.04.037. Epub 2018 May 30.

PMID:
29857009
12.

Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis.

Chen AC, Tran HB, Xi Y, Yerkovich ST, Baines KJ, Pizzutto SJ, Carroll M, Robertson AAB, Cooper MA, Schroder K, Simpson JL, Gibson PG, Hodge G, Masters IB, Buntain HM, Petsky HL, Prime SJ, Chang AB, Hodge S, Upham JW.

ERJ Open Res. 2018 Mar 23;4(1). pii: 00130-2017. doi: 10.1183/23120541.00130-2017. eCollection 2018 Jan.

13.

Airway cells from protracted bacterial bronchitis and bronchiectasis share similar gene expression profiles.

Chen AC, Pena OM, Nel HJ, Yerkovich ST, Chang AB, Baines KJ, Gibson PG, Petsky HL, Pizzutto SJ, Hodge S, Masters IB, Buntain HL, Upham JW.

Pediatr Pulmonol. 2018 May;53(5):575-582. doi: 10.1002/ppul.23984. Epub 2018 Mar 24.

PMID:
29575797
14.

Cytokine responses to two common respiratory pathogens in children are dependent on interleukin-1β.

Chen AC, Xi Y, Carroll M, Petsky HL, Gardiner SJ, Pizzutto SJ, Yerkovich ST, Baines KJ, Gibson PG, Hodge S, Masters IB, Buntain HM, Chang AB, Upham JW.

ERJ Open Res. 2017 Oct 2;3(4). pii: 00025-2017. doi: 10.1183/23120541.00025-2017. eCollection 2017 Oct.

15.

Sputum colour can identify patients with neutrophilic inflammation in asthma.

Pabreja K, Gibson P, Lochrin AJ, Wood L, Baines KJ, Simpson JL.

BMJ Open Respir Res. 2017 Oct 9;4(1):e000236. doi: 10.1136/bmjresp-2017-000236. eCollection 2017.

16.

Short-chain fatty acids, prebiotics, synbiotics, and systemic inflammation: a systematic review and meta-analysis.

McLoughlin RF, Berthon BS, Jensen ME, Baines KJ, Wood LG.

Am J Clin Nutr. 2017 Sep 1;106(3):930-945. doi: 10.3945/ajcn.117.156265.

PMID:
28793992
17.

A sputum gene expression signature predicts oral corticosteroid response in asthma.

Berthon BS, Gibson PG, Wood LG, MacDonald-Wicks LK, Baines KJ.

Eur Respir J. 2017 Jun 29;49(6). pii: 1700180. doi: 10.1183/13993003.00180-2017. Print 2017 Jun.

18.

MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD.

Hsu AC, Dua K, Starkey MR, Haw TJ, Nair PM, Nichol K, Zammit N, Grey ST, Baines KJ, Foster PS, Hansbro PM, Wark PA.

JCI Insight. 2017 Apr 6;2(7):e90443. doi: 10.1172/jci.insight.90443.

19.

Role for NLRP3 Inflammasome-mediated, IL-1β-Dependent Responses in Severe, Steroid-Resistant Asthma.

Kim RY, Pinkerton JW, Essilfie AT, Robertson AAB, Baines KJ, Brown AC, Mayall JR, Ali MK, Starkey MR, Hansbro NG, Hirota JA, Wood LG, Simpson JL, Knight DA, Wark PA, Gibson PG, O'Neill LAJ, Cooper MA, Horvat JC, Hansbro PM.

Am J Respir Crit Care Med. 2017 Aug 1;196(3):283-297. doi: 10.1164/rccm.201609-1830OC.

PMID:
28252317
20.

Airway gene expression of IL-1 pathway mediators predicts exacerbation risk in obstructive airway disease.

Baines KJ, Fu JJ, McDonald VM, Gibson PG.

Int J Chron Obstruct Pulmon Dis. 2017 Feb 8;12:541-550. doi: 10.2147/COPD.S119443. eCollection 2017.

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