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Items: 16

1.

Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial.

Ludolph AC, Schuster J, Dorst J, Dupuis L, Dreyhaupt J, Weishaupt JH, Kassubek J, Weiland U, Petri S, Meyer T, Grosskreutz J, Schrank B, Boentert M, Emmer A, Hermann A, Zeller D, Prudlo J, Winkler AS, Grehl T, Heneka MT, Wollebæk Johannesen S, Göricke B; RAS-ALS Study Group.

Lancet Neurol. 2018 Aug;17(8):681-688. doi: 10.1016/S1474-4422(18)30176-5. Epub 2018 Jun 19.

PMID:
29934198
2.

CatWalk gait analysis in a rat model of multiple sclerosis.

Herold S, Kumar P, Jung K, Graf I, Menkhoff H, Schulz X, Bähr M, Hein K.

BMC Neurosci. 2016 Nov 30;17(1):78.

3.

Disease Activity and Conversion into Multiple Sclerosis after Optic Neuritis Is Treated with Erythropoietin.

Sühs KW, Papanagiotou P, Hein K, Pul R, Scholz K, Heesen C, Diem R.

Int J Mol Sci. 2016 Sep 30;17(10). pii: E1666.

4.

Brain Metabolite Changes in Patients with Relapsing-Remitting and Secondary Progressive Multiple Sclerosis: A Two-Year Follow-Up Study.

Obert D, Helms G, Sättler MB, Jung K, Kretzschmar B, Bähr M, Dechent P, Diem R, Hein K.

PLoS One. 2016 Sep 16;11(9):e0162583. doi: 10.1371/journal.pone.0162583. eCollection 2016.

5.

Treatment of optic neuritis with erythropoietin (TONE): a randomised, double-blind, placebo-controlled trial-study protocol.

Diem R, Molnar F, Beisse F, Gross N, Drüschler K, Heinrich SP, Joachimsen L, Rauer S, Pielen A, Sühs KW, Linker RA, Huchzermeyer C, Albrecht P, Hassenstein A, Aktas O, Guthoff T, Tonagel F, Kernstock C, Hartmann K, Kümpfel T, Hein K, van Oterendorp C, Grotejohann B, Ihorst G, Maurer J, Müller M, Volkmann M, Wildemann B, Platten M, Wick W, Heesen C, Schiefer U, Wolf S, Lagrèze WA.

BMJ Open. 2016 Mar 1;6(3):e010956. doi: 10.1136/bmjopen-2015-010956.

6.

Neurodegeneration in Autoimmune Optic Neuritis Is Associated with Altered APP Cleavage in Neurons and Up-Regulation of p53.

Herold S, Kumar P, Wichert SP, Kretzschmar B, Bähr M, Rossner MJ, Hein K.

PLoS One. 2015 Oct 1;10(10):e0138852. doi: 10.1371/journal.pone.0138852. eCollection 2015.

7.

Systemic Escherichia coli infection does not influence clinical symptoms and neurodegeneration in experimental autoimmune encephalomyelitis.

Kumar P, Friebe K, Schallhorn R, Moinfar Z, Nau R, Bähr M, Schütze S, Hein K.

BMC Neurosci. 2015 Jun 19;16:36. doi: 10.1186/s12868-015-0172-4.

8.

Beneficial effect of chronic Staphylococcus aureus infection in a model of multiple sclerosis is mediated through the secretion of extracellular adherence protein.

Kumar P, Kretzschmar B, Herold S, Nau R, Kreutzfeldt M, Schütze S, Bähr M, Hein K.

J Neuroinflammation. 2015 Feb 3;12:22. doi: 10.1186/s12974-015-0241-8.

9.

Treatment with atacicept enhances neuronal cell death in a rat model of optic neuritis.

Kretzschmar B, Hein K, Moinfar Z, Könnecke B, Sättler MB, Hess H, Weissert R, Bähr M.

J Neuroimmunol. 2014 Mar 15;268(1-2):58-63. doi: 10.1016/j.jneuroim.2014.01.005. Epub 2014 Jan 15.

PMID:
24485150
10.

Functional and structural evaluation of lamotrigine treatment in rat models of acute and chronic ocular hypertension.

Sandalon S, Könnecke B, Levkovitch-Verbin H, Simons M, Hein K, Sättler MB, Bähr M, Ofri R.

Exp Eye Res. 2013 Oct;115:47-56. doi: 10.1016/j.exer.2013.06.018. Epub 2013 Jun 28.

PMID:
23810807
11.

Retinal nerve fibre layer thinning in patients with clinically isolated optic neuritis and early treatment with interferon-beta.

Sühs KW, Hein K, Pehlke JR, Käsmann-Kellner B, Diem R.

PLoS One. 2012;7(12):e51645. doi: 10.1371/journal.pone.0051645. Epub 2012 Dec 13.

12.

A randomized, double-blind, phase 2 study of erythropoietin in optic neuritis.

Sühs KW, Hein K, Sättler MB, Görlitz A, Ciupka C, Scholz K, Käsmann-Kellner B, Papanagiotou P, Schäffler N, Restemeyer C, Bittersohl D, Hassenstein A, Seitz B, Reith W, Fassbender K, Hilgers R, Heesen C, Bähr M, Diem R.

Ann Neurol. 2012 Aug;72(2):199-210. doi: 10.1002/ana.23573.

PMID:
22926853
13.

Author response: Retinal nerve fiber layer thickness measurements in rats with the spectral domain optical coherence tomography.

Lange K, Bähr M, Hein K.

Invest Ophthalmol Vis Sci. 2012 Jun 8;53(7):3570-1. doi: 10.1167/iovs.12-10024. Print 2012 Jun. No abstract available.

PMID:
22685126
14.

An optical coherence tomography study on degeneration of retinal nerve fiber layer in rats with autoimmune optic neuritis.

Hein K, Gadjanski I, Kretzschmar B, Lange K, Diem R, Sättler MB, Bähr M.

Invest Ophthalmol Vis Sci. 2012 Jan 20;53(1):157-63. doi: 10.1167/iovs.11-8092.

PMID:
22131393
15.

Correlation of optical coherence tomography with clinical and histopathological findings in experimental autoimmune uveoretinitis.

Gadjanski I, Williams SK, Hein K, Sättler MB, Bähr M, Diem R.

Exp Eye Res. 2011 Jul;93(1):82-90. doi: 10.1016/j.exer.2011.04.012. Epub 2011 May 11.

PMID:
21586286
16.

Anti-inflammatory effects of FTY720 do not prevent neuronal cell loss in a rat model of optic neuritis.

Rau CR, Hein K, Sättler MB, Kretzschmar B, Hillgruber C, McRae BL, Diem R, Bähr M.

Am J Pathol. 2011 Apr;178(4):1770-81. doi: 10.1016/j.ajpath.2011.01.003. Epub 2011 Feb 26.

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