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Items: 8

1.

No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice.

Iyer V, Boroviak K, Thomas M, Doe B, Riva L, Ryder E, Adams DJ.

PLoS Genet. 2018 Jul 9;14(7):e1007503. doi: 10.1371/journal.pgen.1007503. [Epub ahead of print]

2.

Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome.

Balmus G, Larrieu D, Barros AC, Collins C, Abrudan M, Demir M, Geisler NJ, Lelliott CJ, White JK, Karp NA, Atkinson J, Kirton A, Jacobsen M, Clift D, Rodriguez R; Sanger Mouse Genetics Project, Adams DJ, Jackson SP.

Nat Commun. 2018 Apr 27;9(1):1700. doi: 10.1038/s41467-018-03770-3.

3.

Author Correction: Revealing hidden complexities of genomic rearrangements generated with Cas9.

Boroviak K, Fu B, Yang F, Doe B, Bradley A.

Sci Rep. 2018 Apr 5;8(1):5765. doi: 10.1038/s41598-018-23232-6.

4.

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.

Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bär S, Minocha S, Chevalier C, Po C; Sanger Mouse Genetics Project, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Hérault Y, Collins SC, Friant S, Godin JD, Yalcin B.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317. doi: 10.1073/pnas.1713625114. Epub 2017 Oct 12.

5.

Revealing hidden complexities of genomic rearrangements generated with Cas9.

Boroviak K, Fu B, Yang F, Doe B, Bradley A.

Sci Rep. 2017 Oct 9;7(1):12867. doi: 10.1038/s41598-017-12740-6. Erratum in: Sci Rep. 2018 Apr 5;8(1):5765.

6.

Synthetic lethality between PAXX and XLF in mammalian development.

Balmus G, Barros AC, Wijnhoven PW, Lescale C, Hasse HL, Boroviak K, le Sage C, Doe B, Speak AO, Galli A, Jacobsen M, Deriano L, Adams DJ, Blackford AN, Jackson SP.

Genes Dev. 2016 Oct 1;30(19):2152-2157.

7.

C13orf31 (FAMIN) is a central regulator of immunometabolic function.

Cader MZ, Boroviak K, Zhang Q, Assadi G, Kempster SL, Sewell GW, Saveljeva S, Ashcroft JW, Clare S, Mukhopadhyay S, Brown KP, Tschurtschenthaler M, Raine T, Doe B, Chilvers ER, Griffin JL, Kaneider NC, Floto RA, D'Amato M, Bradley A, Wakelam MJ, Dougan G, Kaser A.

Nat Immunol. 2016 Sep;17(9):1046-56. doi: 10.1038/ni.3532. Epub 2016 Aug 1.

PMID:
27478939
8.

Chromosome engineering in zygotes with CRISPR/Cas9.

Boroviak K, Doe B, Banerjee R, Yang F, Bradley A.

Genesis. 2016 Feb;54(2):78-85. doi: 10.1002/dvg.22915. Epub 2016 Jan 25.

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