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Items: 1 to 20 of 65

1.

Bicuspid Aortic Valve Alters Aortic Protein Expression Profile in Neonatal Coarctation Patients.

Skeffington KL, Bond AR, Abdul-Ghani S, Iacobazzi D, Kang SL, Heesom KJ, Wilson MC, Ghorbel M, Stoica S, Martin R, Suleiman MS, Caputo M.

J Clin Med. 2019 Apr 16;8(4). pii: E517. doi: 10.3390/jcm8040517.

2.

Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms.

Andrew RJ, Fisher K, Heesom KJ, Kellett KAB, Hooper NM.

J Neurochem. 2019 May;149(3):399-412. doi: 10.1111/jnc.14666. Epub 2019 Feb 14.

PMID:
30664241
3.

LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells.

Morgan RG, Ridsdale J, Payne M, Heesom KJ, Wilson MC, Davidson A, Greenhough A, Davies S, Williams AC, Blair A, Waterman ML, Tonks A, Darley RL.

Haematologica. 2019 Jan 10. pii: haematol.2018.202846. doi: 10.3324/haematol.2018.202846. [Epub ahead of print]

4.

Detecting intracellular thiol redox state in leukaemia and heterogeneous immune cell populations: An optimised protocol for digital flow cytometers.

Wadley AJ, Morgan RG, Heesom KJ, Hole PS, Coles SJ.

MethodsX. 2018 Nov 1;5:1473-1483. doi: 10.1016/j.mex.2018.10.013. eCollection 2018.

5.

Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.

Vuolo L, Stevenson NL, Heesom KJ, Stephens DJ.

Elife. 2018 Oct 16;7. pii: e39655. doi: 10.7554/eLife.39655.

6.

SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.

McGough IJ, de Groot REA, Jellett AP, Betist MC, Varandas KC, Danson CM, Heesom KJ, Korswagen HC, Cullen PJ.

Nat Commun. 2018 Sep 13;9(1):3737. doi: 10.1038/s41467-018-06114-3.

7.

Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis.

Greenhough A, Bagley C, Heesom KJ, Gurevich DB, Gay D, Bond M, Collard TJ, Paraskeva C, Martin P, Sansom OJ, Malik K, Williams AC.

EMBO Mol Med. 2018 Nov;10(11). pii: e8699. doi: 10.15252/emmm.201708699.

8.

Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity.

Thomas EC, Hook SC, Gray A, Chadt A, Carling D, Al-Hasani H, Heesom KJ, Hardie DG, Tavaré JM.

Biochem J. 2018 Sep 25;475(18):2969-2983. doi: 10.1042/BCJ20180475.

9.

Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin.

Danson CM, Pearson N, Heesom KJ, Cullen PJ.

J Cell Sci. 2018 Sep 10;131(17). pii: jcs211672. doi: 10.1242/jcs.211672.

10.

Dysregulation of Mesenchymal Stromal Cell Antioxidant Responses in Progressive Multiple Sclerosis.

Redondo J, Sarkar P, Kemp K, Heesom KJ, Wilkins A, Scolding NJ, Rice CM.

Stem Cells Transl Med. 2018 Oct;7(10):748-758. doi: 10.1002/sctm.18-0045. Epub 2018 Jul 31.

11.

Impact of OqxR loss of function on the envelope proteome of Klebsiella pneumoniae and susceptibility to antimicrobials.

Wan Nur Ismah WAK, Takebayashi Y, Findlay J, Heesom KJ, Avison MB.

J Antimicrob Chemother. 2018 Nov 1;73(11):2990-2996. doi: 10.1093/jac/dky293.

PMID:
30053019
12.

Enhancement of red blood cell transfusion compatibility using CRISPR-mediated erythroblast gene editing.

Hawksworth J, Satchwell TJ, Meinders M, Daniels DE, Regan F, Thornton NM, Wilson MC, Dobbe JG, Streekstra GJ, Trakarnsanga K, Heesom KJ, Anstee DJ, Frayne J, Toye AM.

EMBO Mol Med. 2018 Jun;10(6). pii: e8454. doi: 10.15252/emmm.201708454.

13.

Preliminary evidence of reductive stress in human cytotoxic T cells following exercise.

Wadley AJ, Holliday A, Morgan RG, Heesom KJ, Aldred S, Peters DM, Bueno AA, Coles SJ.

J Appl Physiol (1985). 2018 Aug 1;125(2):586-595. doi: 10.1152/japplphysiol.01137.2017. Epub 2018 Apr 12.

PMID:
29648517
14.

Transduction with BBF2H7/CREB3L2 upregulates SEC23A protein in erythroblasts and partially corrects the hypo-glycosylation phenotype associated with CDAII.

Pellegrin S, Haydn-Smith KL, Hampton-O'Neil LA, Hawley BR, Heesom KJ, Fermo E, Bianchi P, Toye AM.

Br J Haematol. 2019 Mar;184(5):876-881. doi: 10.1111/bjh.15189. Epub 2018 Mar 14. No abstract available.

15.

Secretory factors from OP9 stromal cells delay differentiation and increase the expansion potential of adult erythroid cells in vitro.

Trakarnsanga K, Wilson MC, Heesom KJ, Andrienko TN, Srisawat C, Frayne J.

Sci Rep. 2018 Jan 31;8(1):1983. doi: 10.1038/s41598-018-20491-1.

16.

Quantitative proteomics of plasma vesicles identify novel biomarkers for hemoglobin E/β-thalassemic patients.

Kittivorapart J, Crew VK, Wilson MC, Heesom KJ, Siritanaratkul N, Toye AM.

Blood Adv. 2018 Jan 23;2(2):95-104. doi: 10.1182/bloodadvances.2017011726.

17.

Prediction of Fluoroquinolone Susceptibility Directly from Whole-Genome Sequence Data by Using Liquid Chromatography-Tandem Mass Spectrometry To Identify Mutant Genotypes.

Wan Nur Ismah WAK, Takebayashi Y, Findlay J, Heesom KJ, Jiménez-Castellanos JC, Zhang J, Graham L, Bowker K, Williams OM, MacGowan AP, Avison MB.

Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e01814-17. doi: 10.1128/AAC.01814-17. Print 2018 Mar.

18.

In-depth PtdIns(3,4,5)P3 signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function.

Durrant TN, Hutchinson JL, Heesom KJ, Anderson KE, Stephens LR, Hawkins PT, Marshall AJ, Moore SF, Hers I.

Blood Adv. 2017 Jun 13;1(14):918-932. doi: 10.1182/bloodadvances.2017005173.

19.

Envelope proteome changes driven by RamA overproduction in Klebsiella pneumoniae that enhance acquired β-lactam resistance.

Jiménez-Castellanos JC, Wan Nur Ismah WAK, Takebayashi Y, Findlay J, Schneiders T, Heesom KJ, Avison MB.

J Antimicrob Chemother. 2018 Jan 1;73(1):88-94. doi: 10.1093/jac/dkx345.

PMID:
29029194
20.

Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR.

Simonetti B, Danson CM, Heesom KJ, Cullen PJ.

J Cell Biol. 2017 Nov 6;216(11):3695-3712. doi: 10.1083/jcb.201703015. Epub 2017 Sep 21.

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