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Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma.

Cancer Genome Atlas Research Network. Electronic address:; Cancer Genome Atlas Research Network.

Cancer Cell. 2017 Aug 14;32(2):185-203.e13. doi: 10.1016/j.ccell.2017.07.007.


Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking.

Doucet M, Becker KF, Björkman J, Bonnet J, Clément B, Daidone MG, Duyckaerts C, Erb G, Haslacher H, Hofman P, Huppertz B, Junot C, Lundeberg J, Metspalu A, Lavitrano M, Litton JE, Moore HM, Morente M, Naimi BY, Oelmueller U, Ollier B, Parodi B, Ruan L, Stanta G, Turano P, Vaught J, Watson P, Wichmann HE, Yuille M, Zaomi M, Zatloukal K, Dagher G.

Biopreserv Biobank. 2017 Jun;15(3):270-276. doi: 10.1089/bio.2016.0053. Epub 2016 Dec 19. No abstract available.


Federated Biobanking with Corporate Service Unit: The Munich Biobank Alliance Blueprint.

Thasler RM, Berghammer AJ, Kirchner T, Slotta-Huspenina J, Becker KF, Schiergens T, Thasler WE, Wichmann HE.

Biopreserv Biobank. 2017 Feb;15(1):75-79. doi: 10.1089/bio.2016.0101. Epub 2016 Dec 19. No abstract available.


Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer.

Schläfli AM, Adams O, Galván JA, Gugger M, Savic S, Bubendorf L, Schmid RA, Becker KF, Tschan MP, Langer R, Berezowska S.

Oncotarget. 2016 Jun 28;7(26):39544-39555. doi: 10.18632/oncotarget.9647.


Recent progress in protein profiling of clinical tissues for next-generation molecular diagnostics.

Boellner S, Becker KF.

Expert Rev Mol Diagn. 2015;15(10):1277-92. doi: 10.1586/14737159.2015.1070098. Epub 2015 Jul 27. Review.


Quantitative and integrated proteome and microRNA analysis of endothelial replicative senescence.

Yentrapalli R, Azimzadeh O, Kraemer A, Malinowsky K, Sarioglu H, Becker KF, Atkinson MJ, Moertl S, Tapio S.

J Proteomics. 2015 Aug 3;126:12-23. doi: 10.1016/j.jprot.2015.05.023. Epub 2015 May 24.


Critical roles of specimen type and temperature before and during fixation in the detection of phosphoproteins in breast cancer tissues.

Gündisch S, Annaratone L, Beese C, Drecol E, Marchiò C, Quaglino E, Sapino A, Becker KF, Bussolati G.

Lab Invest. 2015 May;95(5):561-71. doi: 10.1038/labinvest.2015.37. Epub 2015 Mar 2.


Using tissue samples for proteomic studies-critical considerations.

Becker KF.

Proteomics Clin Appl. 2015 Apr;9(3-4):257-67. doi: 10.1002/prca.201400106. Epub 2015 Mar 16. Review.


Reverse Phase Protein Arrays-Quantitative Assessment of Multiple Biomarkers in Biopsies for Clinical Use.

Boellner S, Becker KF.

Microarrays (Basel). 2015 Mar 24;4(2):98-114. doi: 10.3390/microarrays4020098. Review.


Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial.

Gündisch S, Slotta-Huspenina J, Verderio P, Ciniselli CM, Pizzamiglio S, Schott C, Drecoll E, Viertler C, Zatloukal K, Kap M, Riegman P, Esposito I, Specht K, Babaryka G, Asslaber M, Bodó K, den Bakker M, den Hollander J, Fend F, Neumann J, Reu S, Perren A, Langer R, Lugli A, Becker I, Richter T, Kayser G, May AM, Carneiro F, Lopes JM, Sobin L, Höfler H, Becker KF.

Virchows Arch. 2014 Nov;465(5):509-19. doi: 10.1007/s00428-014-1624-4. Epub 2014 Aug 2.


Heat Shock Protein 90 (HSP90) and Her2 in Adenocarcinomas of the Esophagus.

Slotta-Huspenina J, Becker KF, Feith M, Walch A, Langer R.

Cancers (Basel). 2014 Jun 27;6(3):1382-93. doi: 10.3390/cancers6031382.


Realizing the promise of reverse phase protein arrays for clinical, translational, and basic research: a workshop report: the RPPA (Reverse Phase Protein Array) society.

Akbani R, Becker KF, Carragher N, Goldstein T, de Koning L, Korf U, Liotta L, Mills GB, Nishizuka SS, Pawlak M, Petricoin EF 3rd, Pollard HB, Serrels B, Zhu J.

Mol Cell Proteomics. 2014 Jul;13(7):1625-43. doi: 10.1074/mcp.O113.034918. Epub 2014 Apr 28.


Variation in cell signaling protein expression may introduce sampling bias in primary epithelial ovarian cancer.

Mittermeyer G, Malinowsky K, Beese C, Höfler H, Schmalfeldt B, Becker KF, Avril S.

PLoS One. 2013 Oct 28;8(10):e77825. doi: 10.1371/journal.pone.0077825. eCollection 2013.


Delayed times to tissue fixation result in unpredictable global phosphoproteome changes.

Gündisch S, Grundner-Culemann K, Wolff C, Schott C, Reischauer B, Machatti M, Groelz D, Schaab C, Tebbe A, Becker KF.

J Proteome Res. 2013 Oct 4;12(10):4424-34. doi: 10.1021/pr400451z. Epub 2013 Sep 17.


The PI3K/Akt/mTOR pathway is implicated in the premature senescence of primary human endothelial cells exposed to chronic radiation.

Yentrapalli R, Azimzadeh O, Sriharshan A, Malinowsky K, Merl J, Wojcik A, Harms-Ringdahl M, Atkinson MJ, Becker KF, Haghdoost S, Tapio S.

PLoS One. 2013 Aug 1;8(8):e70024. doi: 10.1371/journal.pone.0070024. Print 2013.


Characterization of signalling pathways by reverse phase protein arrays.

Malinowsky K, Wolff C, Schott C, Becker KF.

Methods Mol Biol. 2013;1049:285-99. doi: 10.1007/978-1-62703-547-7_21.


The PAXgene(®) tissue system preserves phosphoproteins in human tissue specimens and enables comprehensive protein biomarker research.

Gündisch S, Schott C, Wolff C, Tran K, Beese C, Viertler C, Zatloukal K, Becker KF.

PLoS One. 2013;8(3):e60638. doi: 10.1371/journal.pone.0060638. Epub 2013 Mar 29.


Variability of protein and phosphoprotein levels in clinical tissue specimens during the preanalytical phase.

Gündisch S, Hauck S, Sarioglu H, Schott C, Viertler C, Kap M, Schuster T, Reischauer B, Rosenberg R, Verhoef C, Mischinger HJ, Riegman P, Zatloukal K, Becker KF.

J Proteome Res. 2012 Dec 7;11(12):5748-62. doi: 10.1021/pr300560y. Epub 2012 Nov 16.


Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping.

Wulfkuhle JD, Berg D, Wolff C, Langer R, Tran K, Illi J, Espina V, Pierobon M, Deng J, DeMichele A, Walch A, Bronger H, Becker I, Waldhör C, Höfler H, Esserman L; I-SPY 1 TRIAL Investigators, Liotta LA, Becker KF, Petricoin EF 3rd.

Clin Cancer Res. 2012 Dec 1;18(23):6426-35. doi: 10.1158/1078-0432.CCR-12-0452. Epub 2012 Oct 8.


Evidence of prognostic relevant expression profiles of heat-shock proteins and glucose-regulated proteins in oesophageal adenocarcinomas.

Slotta-Huspenina J, Berg D, Bauer K, Wolff C, Malinowsky K, Bauer L, Drecoll E, Bettstetter M, Feith M, Walch A, Höfler H, Becker KF, Langer R.

PLoS One. 2012;7(7):e41420. doi: 10.1371/journal.pone.0041420. Epub 2012 Jul 24.

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