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Items: 1 to 20 of 90


The ABCG2 multidrug transporter is a pump gated by a valve and an extracellular lid.

Khunweeraphong N, Szöllősi D, Stockner T, Kuchler K.

Nat Commun. 2019 Nov 28;10(1):5433. doi: 10.1038/s41467-019-13302-2.


Pathogenetic Impact of Bacterial-Fungal Interactions.

Nogueira F, Sharghi S, Kuchler K, Lion T.

Microorganisms. 2019 Oct 16;7(10). pii: E459. doi: 10.3390/microorganisms7100459. Review.


A Histone Acetyltransferase Inhibitor with Antifungal Activity against CTG clade Candida Species.

Tscherner M, Kuchler K.

Microorganisms. 2019 Jul 15;7(7). pii: E201. doi: 10.3390/microorganisms7070201.


The Fungal Histone Acetyl Transferase Gcn5 Controls Virulence of the Human Pathogen Candida albicans through Multiple Pathways.

Shivarathri R, Tscherner M, Zwolanek F, Singh NK, Chauhan N, Kuchler K.

Sci Rep. 2019 Jul 1;9(1):9445. doi: 10.1038/s41598-019-45817-5.


Methionine is required for cAMP-PKA mediated morphogenesis and virulence of Candida albicans.

Schrevens S, Van Zeebroeck G, Riedelberger M, Tournu H, Kuchler K, Van Dijck P.

Mol Microbiol. 2018 Aug;109(3):415-416. doi: 10.1111/mmi.14065. Epub 2018 Jul 24. No abstract available.


Remodeling of the Candida glabrata cell wall in the gastrointestinal tract affects the gut microbiota and the immune response.

Charlet R, Pruvost Y, Tumba G, Istel F, Poulain D, Kuchler K, Sendid B, Jawhara S.

Sci Rep. 2018 Feb 20;8(1):3316. doi: 10.1038/s41598-018-21422-w.


Methionine is required for cAMP-PKA-mediated morphogenesis and virulence of Candida albicans.

Schrevens S, Van Zeebroeck G, Riedelberger M, Tournu H, Kuchler K, Van Dijck P.

Mol Microbiol. 2018 May;108(3):258-275. doi: 10.1111/mmi.13933. Epub 2018 Mar 6. Erratum in: Mol Microbiol. 2018 Aug;109(3):415-416.


The structure of the human ABC transporter ABCG2 reveals a novel mechanism for drug extrusion.

Khunweeraphong N, Stockner T, Kuchler K.

Sci Rep. 2017 Oct 23;7(1):13767. doi: 10.1038/s41598-017-11794-w.


The Candida albicans HIR histone chaperone regulates the yeast-to-hyphae transition by controlling the sensitivity to morphogenesis signals.

Jenull S, Tscherner M, Gulati M, Nobile CJ, Chauhan N, Kuchler K.

Sci Rep. 2017 Aug 16;7(1):8308. doi: 10.1038/s41598-017-08239-9.


The Paralogous Histone Deacetylases Rpd3 and Rpd31 Play Opposing Roles in Regulating the White-Opaque Switch in the Fungal Pathogen Candida albicans.

Xie J, Jenull S, Tscherner M, Kuchler K.

MBio. 2016 Nov 15;7(6). pii: e01807-16. doi: 10.1128/mBio.01807-16.


Immunological Identification of Fungal Species.

Nogueira F, Istel F, Pereira L, Tscherner M, Kuchler K.

Methods Mol Biol. 2017;1508:339-359.


Fungal KATs/KDACs: A New Highway to Better Antifungal Drugs?

Kuchler K, Jenull S, Shivarathri R, Chauhan N.

PLoS Pathog. 2016 Nov 10;12(11):e1005938. doi: 10.1371/journal.ppat.1005938. eCollection 2016 Nov. Review. No abstract available.


Inhibition of CBLB protects from lethal Candida albicans sepsis.

Wirnsberger G, Zwolanek F, Asaoka T, Kozieradzki I, Tortola L, Wimmer RA, Kavirayani A, Fresser F, Baier G, Langdon WY, Ikeda F, Kuchler K, Penninger JM.

Nat Med. 2016 Aug;22(8):915-23. doi: 10.1038/nm.4134. Epub 2016 Jul 18.


Dectin-1 is required for miR155 upregulation in murine macrophages in response to Candida albicans.

Agustinho DP, de Oliveira MA, Tavares AH, Derengowski L, Stolz V, Guilhelmelli F, Mortari MR, Kuchler K, Silva-Pereira I.

Virulence. 2017 Jan 2;8(1):41-52. doi: 10.1080/21505594.2016.1200215. Epub 2016 Jun 13.


Subtle Structural Differences Trigger Inhibitory Activity of Propafenone Analogues at the Two Polyspecific ABC Transporters: P-Glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP).

Schwarz T, Montanari F, Cseke A, Wlcek K, Visvader L, Palme S, Chiba P, Kuchler K, Urban E, Ecker GF.

ChemMedChem. 2016 Jun 20;11(12):1380-94. doi: 10.1002/cmdc.201500592. Epub 2016 Mar 10.


Flagging Drugs That Inhibit the Bile Salt Export Pump.

Montanari F, Pinto M, Khunweeraphong N, Wlcek K, Sohail MI, Noeske T, Boyer S, Chiba P, Stieger B, Kuchler K, Ecker GF.

Mol Pharm. 2016 Jan 4;13(1):163-71. doi: 10.1021/acs.molpharmaceut.5b00594. Epub 2015 Dec 21.


The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly Pathways.

Tscherner M, Zwolanek F, Jenull S, Sedlazeck FJ, Petryshyn A, Frohner IE, Mavrianos J, Chauhan N, von Haeseler A, Kuchler K.

PLoS Pathog. 2015 Oct 16;11(10):e1005218. doi: 10.1371/journal.ppat.1005218. eCollection 2015 Oct.


Candida glabrata susceptibility to antifungals and phagocytosis is modulated by acetate.

Mota S, Alves R, Carneiro C, Silva S, Brown AJ, Istel F, Kuchler K, Sampaio P, Casal M, Henriques M, Paiva S.

Front Microbiol. 2015 Sep 4;6:919. doi: 10.3389/fmicb.2015.00919. eCollection 2015.


Genetic Transformation of Candida glabrata by Electroporation.

Istel F, Schwarzmüller T, Tscherner M, Kuchler K.

Bio Protoc. 2015 Jul 20;5(14). pii: e1528. doi: 10.21769/BioProtoc.1528.


Large-scale Phenotypic Profiling of Gene Deletion Mutants in Candida glabrata.

Istel F, Schwarzmüller T, Tscherner M, Kuchler K.

Bio Protoc. 2015 Jul 20;5(14). pii: e1530. doi: 10.21769/BioProtoc.1530.

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