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Items: 1 to 20 of 333


Pharmacokinetic modeling of intravenous sildenafil in newborns with congenital diaphragmatic hernia.

Cochius-den Otter SCM, Kipfmueller F, de Winter BCM, Allegaert K, Tibboel D, Mueller A, Koch BCP.

Eur J Clin Pharmacol. 2019 Nov 18. doi: 10.1007/s00228-019-02767-1. [Epub ahead of print]


Standardizing Safety Assessment and Reporting for Neonatal Clinical Trials.

Davis JM, Baer GR, McCune S, Klein A, Sato J, Fabbri L, Mangili A, Short MA, Tansey S, Mangum B, Hokuto I, Nakamura H, Salaets T, Allegaert K, Yao L, Blum M, Toerner J, Turner M, Portman R; International Neonatal Consortium.

J Pediatr. 2019 Nov 7. pii: S0022-3476(19)31295-8. doi: 10.1016/j.jpeds.2019.09.060. [Epub ahead of print] No abstract available.


The CoDiNOS trial protocol: an international randomised controlled trial of intravenous sildenafil versus inhaled nitric oxide for the treatment of pulmonary hypertension in neonates with congenital diaphragmatic hernia.

Cochius-den Otter S, Schaible T, Greenough A, van Heijst A, Patel N, Allegaert K, van Rosmalen J, Tibboel D; CDH EURO Consortium.

BMJ Open. 2019 Nov 5;9(11):e032122. doi: 10.1136/bmjopen-2019-032122.


A sensitive liquid chromatography method for analysis of propofol in small volumes of neonatal blood.

Qi B, Nicolaï J, Smits A, De Vocht T, Deferm N, Van Brantegem P, Allegaert K, Annaert P.

J Clin Pharm Ther. 2019 Oct 3. doi: 10.1111/jcpt.13038. [Epub ahead of print]


Drug Disposition and Pharmacotherapy in Neonatal ECMO: From Fragmented Data to Integrated Knowledge.

Raffaeli G, Pokorna P, Allegaert K, Mosca F, Cavallaro G, Wildschut ED, Tibboel D.

Front Pediatr. 2019 Sep 3;7:360. doi: 10.3389/fped.2019.00360. eCollection 2019. Review.


Development of a neonatal adverse event severity scale through a Delphi consensus approach.

Salaets T, Turner MA, Short M, Ward RM, Hokuto I, Ariagno RL, Klein A, Beauman S, Wade K, Thomson M, Roberts E, Harrison J, Quinn T, Baer G, Davis J, Allegaert K; International Neonatal Consortium.

Arch Dis Child. 2019 Dec;104(12):1167-1173. doi: 10.1136/archdischild-2019-317399. Epub 2019 Sep 19.


Extremely Low Birth Weight Predisposes to Impaired Renal Health: A Pooled Analysis.

Gilarska M, Raaijmakers A, Zhang ZY, Staessen JA, Levtchenko E, Klimek M, Grudzień A, Starzec K, Allegaert K, Kwinta P.

Kidney Blood Press Res. 2019;44(5):897-906. doi: 10.1159/000502715. Epub 2019 Sep 19.


Medical devices that look like medicines: safety and regulatory concerns for children in Europe.

Huijghebaert S, De Bruyne P, Allegaert K, Vande Velde S, De Bruyne R, Van Biervliet S, Van Winckel M.

Arch Dis Child. 2019 Sep 18. pii: archdischild-2018-316391. doi: 10.1136/archdischild-2018-316391. [Epub ahead of print]


Ontogeny of Phase I Metabolism of Drugs.

Allegaert K, van den Anker J.

J Clin Pharmacol. 2019 Sep;59 Suppl 1:S33-S41. doi: 10.1002/jcph.1483.


Rapidly maturing fentanyl clearance in preterm neonates.

Völler S, Flint RB, Andriessen P, Allegaert K, Zimmermann LJI, Liem KD, Koch BCP, Simons SHP, Knibbe CAJ; DINO study group.

Arch Dis Child Fetal Neonatal Ed. 2019 Nov;104(6):F598-F603. doi: 10.1136/archdischild-2018-315920. Epub 2019 Feb 1.


Propofol Formulation Affects Myocardial Function in Newborn Infants.

Massolo AC, Sgrò S, Piersigilli F, Allegaert K, Capolupo I, Rechichi J, Landolfo F, Calzolari F, Toscano A, Picardo S, Patel N.

Pediatr Cardiol. 2019 Oct;40(7):1536-1542. doi: 10.1007/s00246-019-02182-4. Epub 2019 Aug 14.


Pharmacokinetic modelling and Bayesian estimation-assisted decision tools to optimize vancomycin dosage in neonates: only one piece of the puzzle.

Allegaert K, Flint R, Smits A.

Expert Opin Drug Metab Toxicol. 2019 Sep;15(9):735-749. doi: 10.1080/17425255.2019.1655540. Epub 2019 Aug 19. Review.


Physiologically Based Pharmacokinetic Modeling to Characterize Acetaminophen Pharmacokinetics and N-Acetyl-p-Benzoquinone Imine (NAPQI) Formation in Non-Pregnant and Pregnant Women.

Mian P, van den Anker JN, van Calsteren K, Annaert P, Tibboel D, Pfister M, Allegaert K, Dallmann A.

Clin Pharmacokinet. 2019 Jul 25. doi: 10.1007/s40262-019-00799-5. [Epub ahead of print]


Health products' and substance use among pregnant women visiting a tertiary hospital in Belgium: A cross-sectional study.

Ceulemans M, Van Calsteren K, Allegaert K, Foulon V.

Pharmacoepidemiol Drug Saf. 2019 Sep;28(9):1231-1238. doi: 10.1002/pds.4862. Epub 2019 Jul 25.


A manual propofol infusion regimen for neonates and infants.

Morse J, Hannam JA, Cortinez LI, Allegaert K, Anderson BJ.

Paediatr Anaesth. 2019 Sep;29(9):907-914. doi: 10.1111/pan.13706. Epub 2019 Aug 12.


Dose rationale and pharmacokinetics of dexmedetomidine in mechanically ventilated new-borns: impact of design optimisation.

van Dijkman SC, De Cock PAJG, Smets K, Decaluwe W, Smits A, Allegaert K, Vande Walle J, De Paepe P, Della Pasqua O.

Eur J Clin Pharmacol. 2019 Oct;75(10):1393-1404. doi: 10.1007/s00228-019-02708-y. Epub 2019 Jul 16.


Prevalence and characteristics of pregnancy- and lactation-related calls to the National Poison Centre in Belgium: A retrospective analysis of calls from 2012 to 2017.

Ceulemans M, Fortuin M, Van Calsteren K, Allegaert K, Foulon V.

J Eval Clin Pract. 2019 Jul 12. doi: 10.1111/jep.13228. [Epub ahead of print]


RAIN study: a protocol for a randomised controlled trial evaluating efficacy, safety and cost-effectiveness of intravenous-to-oral antibiotic switch therapy in neonates with a probable bacterial infection.

Keij FM, Kornelisse RF, Hartwig NG, Mauff K, Poley MJ, Allegaert K, Reiss IKM, Tramper-Stranders GA.

BMJ Open. 2019 Jul 9;9(7):e026688. doi: 10.1136/bmjopen-2018-026688.


Effect of allopurinol in addition to hypothermia treatment in neonates for hypoxic-ischemic brain injury on neurocognitive outcome (ALBINO): study protocol of a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III).

Maiwald CA, Annink KV, Rüdiger M, Benders MJNL, van Bel F, Allegaert K, Naulaers G, Bassler D, Klebermaß-Schrehof K, Vento M, Guimarães H, Stiris T, Cattarossi L, Metsäranta M, Vanhatalo S, Mazela J, Metsvaht T, Jacobs Y, Franz AR; ALBINO Study Group.

BMC Pediatr. 2019 Jun 27;19(1):210. doi: 10.1186/s12887-019-1566-8.


Oral antibiotics for neonatal infections: a systematic review and meta-analysis.

Keij FM, Kornelisse RF, Hartwig NG, Reiss IKM, Allegaert K, Tramper-Stranders GA.

J Antimicrob Chemother. 2019 Nov 1;74(11):3150-3161. doi: 10.1093/jac/dkz252.

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