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Items: 10

1.

An engineered bispecific DNA-encoded IgG antibody protects against Pseudomonas aeruginosa in a pneumonia challenge model.

Patel A, DiGiandomenico A, Keller AE, Smith TRF, Park DH, Ramos S, Schultheis K, Elliott STC, Mendoza J, Broderick KE, Wise MC, Yan J, Jiang J, Flingai S, Khan AS, Muthumani K, Humeau L, Cheng LI, Wachter-Rosati L, Stover CK, Sardesai NY, Weiner DB.

Nat Commun. 2017 Sep 21;8(1):637. doi: 10.1038/s41467-017-00576-7.

PMID:
28935938
2.

Novel prostate cancer immunotherapy with a DNA-encoded anti-prostate-specific membrane antigen monoclonal antibody.

Muthumani K, Marnin L, Kudchodkar SB, Perales-Puchalt A, Choi H, Agarwal S, Scott VL, Reuschel EL, Zaidi FI, Duperret EK, Wise MC, Kraynyak KA, Ugen KE, Sardesai NY, Joseph Kim J, Weiner DB.

Cancer Immunol Immunother. 2017 Aug 17. doi: 10.1007/s00262-017-2042-7. [Epub ahead of print]

PMID:
28819703
3.

HIV and HIV-Tat inhibit LPS-induced IL-27 production in human macrophages by distinct intracellular signaling pathways.

Gajanayaka N, O'Hara S, Konarski Y, Fernandes J, Muthumani K, Kozlowski M, Angel JB, Kumar A.

J Leukoc Biol. 2017 Sep;102(3):925-939. doi: 10.1189/jlb.4A0716-332RR. Epub 2017 Jul 11.

PMID:
28698313
4.

DNA vaccination protects mice against Zika virus-induced damage to the testes.

Griffin BD, Muthumani K, Warner BM, Majer A, Hagan M, Audet J, Stein DR, Ranadheera C, Racine T, De La Vega MA, Piret J, Kucas S, Tran KN, Frost KL, De Graff C, Soule G, Scharikow L, Scott J, McTavish G, Smid V, Park YK, Maslow JN, Sardesai NY, Kim JJ, Yao XJ, Bello A, Lindsay R, Boivin G, Booth SA, Kobasa D, Embury-Hyatt C, Safronetz D, Weiner DB, Kobinger GP.

Nat Commun. 2017 Jun 7;8:15743. doi: 10.1038/ncomms15743.

5.

Protocols for Developing Novel Chikungunya Virus DNA Vaccines.

Chung C, Ugen KE, Sardesai NY, Weiner DB, Muthumani K.

Methods Mol Biol. 2016;1426:311-32. doi: 10.1007/978-1-4939-3618-2_28.

PMID:
27233283
6.

Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy.

Flingai S, Plummer EM, Patel A, Shresta S, Mendoza JM, Broderick KE, Sardesai NY, Muthumani K, Weiner DB.

Sci Rep. 2015 Jul 29;5:12616. doi: 10.1038/srep12616.

7.

HIV-1 Env DNA vaccine plus protein boost delivered by EP expands B- and T-cell responses and neutralizing phenotype in vivo.

Muthumani K, Wise MC, Broderick KE, Hutnick N, Goodman J, Flingai S, Yan J, Bian CB, Mendoza J, Tingey C, Wilson C, Wojtak K, Sardesai NY, Weiner DB.

PLoS One. 2013 Dec 31;8(12):e84234. doi: 10.1371/journal.pone.0084234. eCollection 2013.

8.

Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity.

Shedlock DJ, Tingey C, Mahadevan L, Hutnick N, Reuschel EL, Kudchodkar S, Flingai S, Yan J, Kim JJ, Ugen KE, Weiner DB, Muthumani K.

Vaccines (Basel). 2014 Mar 25;2(2):196-215. doi: 10.3390/vaccines2020196.

9.

Synthetic DNA vaccines: improved vaccine potency by electroporation and co-delivered genetic adjuvants.

Flingai S, Czerwonko M, Goodman J, Kudchodkar SB, Muthumani K, Weiner DB.

Front Immunol. 2013 Nov 4;4:354. doi: 10.3389/fimmu.2013.00354. Review.

10.

Optimized and enhanced DNA plasmid vector based in vivo construction of a neutralizing anti-HIV-1 envelope glycoprotein Fab.

Muthumani K, Flingai S, Wise M, Tingey C, Ugen KE, Weiner DB.

Hum Vaccin Immunother. 2013 Oct;9(10):2253-62. doi: 10.4161/hv.26498. Epub 2013 Sep 17.

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