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Items: 1 to 20 of 85


Jie Du Tong Ye San Prevents N-Nitrosomethylbenzylamine-Induced Esophageal Carcinogenesis via Inhibition of Inflammation and Proliferation.

Zhao S, Jiang Y, Tian T, Zhao J, Xie Y, Chen X, Lu J, Yang F, Li H, Liu K, Dong Z.

Evid Based Complement Alternat Med. 2019 May 20;2019:5752670. doi: 10.1155/2019/5752670. eCollection 2019.


Lapachol is a novel ribosomal protein S6 kinase 2 inhibitor that suppresses growth and induces intrinsic apoptosis in esophageal squamous cell carcinoma cells.

Zu X, Xie X, Zhang Y, Liu K, Bode AM, Dong Z, Kim DJ.

Phytother Res. 2019 Jun 21. doi: 10.1002/ptr.6415. [Epub ahead of print]


Improved Antitumor Efficacy of Combined Vaccine Based on the Induced HUVECs and DC-CT26 Against Colorectal Carcinoma.

Zhang Q, Xie C, Wang D, Yang Y, Liu H, Liu K, Zhao J, Chen X, Zhang X, Yang W, Li X, Tian F, Dong Z, Lu J.

Cells. 2019 May 22;8(5). pii: E494. doi: 10.3390/cells8050494.


Purpurogallin is a novel mitogen-activated protein kinase kinase 1/2 inhibitor that suppresses esophageal squamous cell carcinoma growth in vitro and in vivo.

Xie X, Zu X, Liu F, Wang T, Wang X, Chen H, Liu K, Wang P, Liu F, Zheng Y, Bode AM, Dong Z, Kim DJ.

Mol Carcinog. 2019 Jul;58(7):1248-1259. doi: 10.1002/mc.23007. Epub 2019 May 17.


Inhibition of LTA4H by bestatin in human and mouse colorectal cancer.

Zhao S, Yao K, Li D, Liu K, Jin G, Yan M, Wu Q, Chen H, Shin SH, Bai R, Wang G, Bode AM, Dong Z, Guo Z, Dong Z.

EBioMedicine. 2019 Jun;44:361-374. doi: 10.1016/j.ebiom.2019.05.008. Epub 2019 May 10.


Analysis of hydrophobic and hydrophilic moments of short penetrating peptides for enhancing mitochondrial localization: prediction and validation.

Pirisinu M, Blasco P, Tian X, Sen Y, Bode AM, Liu K, Dong Z.

FASEB J. 2019 Jul;33(7):7970-7984. doi: 10.1096/fj.201802748RR. Epub 2019 Mar 27.


Targeted therapy of the AKT kinase inhibits esophageal squamous cell carcinoma growth in vitro and in vivo.

Liu X, Song M, Wang P, Zhao R, Chen H, Zhang M, Shi Y, Liu K, Liu F, Yang R, Li E, Bode AM, Dong Z, Lee MH.

Int J Cancer. 2019 Aug 15;145(4):1007-1019. doi: 10.1002/ijc.32285. Epub 2019 Apr 3.


Lin28a expression protects against streptozotocin-induced β-cell destruction and prevents diabetes in mice.

Sung Y, Jeong J, Kang RJ, Choi M, Park S, Kwon W, Lee J, Jang S, Park SJ, Kim SH, Yi J, Choi SK, Lee MH, Liu K, Dong Z, Ryoo ZY, Kim MO.

Cell Biochem Funct. 2019 Apr;37(3):139-147. doi: 10.1002/cbf.3376. Epub 2019 Mar 18.


Aurora B kinase as a novel molecular target for inhibition the growth of osteosarcoma.

Zhao Z, Jin G, Yao K, Liu K, Liu F, Chen H, Wang K, Gorja DR, Reddy K, Bode AM, Guo Z, Dong Z.

Mol Carcinog. 2019 Jun;58(6):1056-1067. doi: 10.1002/mc.22993. Epub 2019 Mar 1.


3,3'-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX1/2 and ERK1/2.

Tian X, Liu K, Zu X, Ma F, Li Z, Lee M, Chen H, Li Y, Zhao Y, Liu F, Oi N, Bode AM, Dong Z, Kim DJ.

Cancer Lett. 2019 Apr 28;448:20-30. doi: 10.1016/j.canlet.2019.01.031. Epub 2019 Feb 1.


Gossypin inhibits gastric cancer growth by direct targeting of AURKA and RSK2.

Wang L, Wang X, Chen H, Zu X, Ma F, Liu K, Bode AM, Dong Z, Kim DJ.

Phytother Res. 2019 Mar;33(3):640-650. doi: 10.1002/ptr.6253. Epub 2018 Dec 10.


Ethyl gallate as a novel ERK1/2 inhibitor suppresses patient-derived esophageal tumor growth.

Liu F, Zu X, Xie X, Liu K, Chen H, Wang T, Liu F, Bode AM, Zheng Y, Dong Z, Kim DJ.

Mol Carcinog. 2019 Apr;58(4):533-543. doi: 10.1002/mc.22948. Epub 2018 Dec 21.


Gossypetin is a novel MKK3 and MKK6 inhibitor that suppresses esophageal cancer growth in vitro and in vivo.

Xie X, Liu K, Liu F, Chen H, Wang X, Zu X, Ma X, Wang T, Wu Q, Zheng Y, Bode AM, Dong Z, Kim DJ.

Cancer Lett. 2019 Feb 1;442:126-136. doi: 10.1016/j.canlet.2018.10.016. Epub 2018 Nov 2.


Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2.

Wang L, Zhang Y, Liu K, Chen H, Yang R, Ma X, Kim HG, Bode AM, Kim DJ, Dong Z.

Oncotarget. 2018 Feb 6;9(76):34200-34212. doi: 10.18632/oncotarget.24409. eCollection 2018 Sep 28.


Aloe emodin suppresses EGF‑induced neoplastic cell transformation by inhibiting the ERK/MSK1 and AKT/GSK3β signaling pathways.

Zhang J, Guo L, Zhang Q, Liu K, Dong Z.

Mol Med Rep. 2018 Dec;18(6):5215-5220. doi: 10.3892/mmr.2018.9517. Epub 2018 Sep 27.


Human umbilical vein endothelial cell vaccine suppresses the angiogenesis of esophageal squamous cell carcinoma in a humanized mouse model.

Liu H, Zhao J, Yang Y, Jin G, Zhang X, Wang D, Xie C, Liu K, Chen X, Li X, Tian F, Dong Z, Lu J.

Oncol Rep. 2018 Nov;40(5):3006-3014. doi: 10.3892/or.2018.6653. Epub 2018 Aug 17.


Quercetin-3-methyl ether inhibits esophageal carcinogenesis by targeting the AKT/mTOR/p70S6K and MAPK pathways.

Zhao S, Jiang Y, Zhao J, Li H, Yin X, Wang Y, Xie Y, Chen X, Lu J, Dong Z, Liu K.

Mol Carcinog. 2018 Nov;57(11):1540-1552. doi: 10.1002/mc.22876. Epub 2018 Aug 28.


Establishment of lung cancer patient-derived xenograft models and primary cell lines for lung cancer study.

Jiang Y, Zhao J, Zhang Y, Li K, Li T, Chen X, Zhao S, Zhao S, Liu K, Dong Z.

J Transl Med. 2018 May 22;16(1):138. doi: 10.1186/s12967-018-1516-5.


Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo.

Song M, Liu X, Liu K, Zhao R, Huang H, Shi Y, Zhang M, Zhou S, Xie H, Chen H, Li Y, Zheng Y, Wu Q, Liu F, Li E, Bode AM, Dong Z, Lee MH.

Mol Cancer Ther. 2018 Jul;17(7):1540-1553. doi: 10.1158/1535-7163.MCT-17-0823. Epub 2018 Apr 25.


Eupatilin inhibits the proliferation of human esophageal cancer TE1 cells by targeting the Akt‑GSK3β and MAPK/ERK signaling cascades.

Wang X, Zhu Y, Zhu L, Chen X, Xu Y, Zhao Y, Shao Y, Li F, Jiang Y, Lu J, Huang Y, Chang X, Zhang J, Li X, Liu K, Zhao M, Dong Z, Zhao J.

Oncol Rep. 2018 Jun;39(6):2942-2950. doi: 10.3892/or.2018.6390. Epub 2018 Apr 23.


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