Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 215

1.

SQSTM1/p62 regulates the production of IL-8 and MCP-1 in IL-1β-stimulated human retinal pigment epithelial cells.

Korhonen E, Piippo N, Hytti M, Hyttinen JMT, Kaarniranta K, Kauppinen A.

Cytokine. 2019 Apr;116:70-77. doi: 10.1016/j.cyto.2018.12.015. Epub 2019 Jan 24.

PMID:
30685605
2.

The first ophthalmic Choosing Wisely recommendations in Finland for glaucoma and wet age-related macular degeneration.

Tuuminen R, Sipilä R, Komulainen J, Saarela V, Kaarniranta K, Tuulonen A.

Acta Ophthalmol. 2019 Jan 18. doi: 10.1111/aos.14031. [Epub ahead of print] No abstract available.

PMID:
30659781
3.

Interplay between Autophagy and the Ubiquitin-Proteasome System and Its Role in the Pathogenesis of Age-Related Macular Degeneration.

Blasiak J, Pawlowska E, Szczepanska J, Kaarniranta K.

Int J Mol Sci. 2019 Jan 8;20(1). pii: E210. doi: 10.3390/ijms20010210. Review.

4.

Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage.

Zeiner J, Loukovaara S, Losenkova K, Zuccarini M, Korhonen AM, Lehti K, Kauppinen A, Kaarniranta K, Müller CE, Jalkanen S, Yegutkin GG.

J Mol Med (Berl). 2019 Jan 7. doi: 10.1007/s00109-018-01734-0. [Epub ahead of print]

PMID:
30617853
5.

Survival and functionality of xeno-free human embryonic stem cell-derived retinal pigment epithelial cells on polyester substrate after transplantation in rabbits.

Ilmarinen T, Thieltges F, Hongisto H, Juuti-Uusitalo K, Koistinen A, Kaarniranta K, Brinken R, Braun N, Holz FG, Skottman H, Stanzel BV.

Acta Ophthalmol. 2018 Dec 28. doi: 10.1111/aos.14004. [Epub ahead of print]

PMID:
30593729
6.

Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.

Felszeghy S, Viiri J, Paterno JJ, Hyttinen JMT, Koskela A, Chen M, Leinonen H, Tanila H, Kivinen N, Koistinen A, Toropainen E, Amadio M, Smedowski A, Reinisalo M, Winiarczyk M, Mackiewicz J, Mutikainen M, Ruotsalainen AK, Kettunen M, Jokivarsi K, Sinha D, Kinnunen K, Petrovski G, Blasiak J, Bjørkøy G, Koskelainen A, Skottman H, Urtti A, Salminen A, Kannan R, Ferrington DA, Xu H, Levonen AL, Tavi P, Kauppinen A, Kaarniranta K.

Redox Biol. 2019 Jan;20:1-12. doi: 10.1016/j.redox.2018.09.011. Epub 2018 Sep 14.

7.

The role of myeloid-derived suppressor cells (MDSC) in the inflammaging process.

Salminen A, Kaarniranta K, Kauppinen A.

Ageing Res Rev. 2018 Dec;48:1-10. doi: 10.1016/j.arr.2018.09.001. Epub 2018 Sep 21. Review.

PMID:
30248408
8.

Oxidative Stress is the Principal Contributor to Inflammasome Activation in Retinal Pigment Epithelium Cells with Defunct Proteasomes and Autophagy.

Piippo N, Korhonen E, Hytti M, Kinnunen K, Kaarniranta K, Kauppinen A.

Cell Physiol Biochem. 2018;49(1):359-367. doi: 10.1159/000492886. Epub 2018 Aug 23.

9.

PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis.

Kaarniranta K, Kajdanek J, Morawiec J, Pawlowska E, Blasiak J.

Int J Mol Sci. 2018 Aug 7;19(8). pii: E2317. doi: 10.3390/ijms19082317. Review.

10.

Wound healing of human embryonic stem cell-derived retinal pigment epithelial cells is affected by maturation stage.

Abu Khamidakh AE, Rodriguez-Martinez A, Kaarniranta K, Kallioniemi A, Skottman H, Hyttinen J, Juuti-Uusitalo K.

Biomed Eng Online. 2018 Jul 31;17(1):102. doi: 10.1186/s12938-018-0535-z.

11.

Fatty acids and oxidized lipoproteins contribute to autophagy and innate immunity responses upon the degeneration of retinal pigment epithelium and development of age-related macular degeneration.

Kaarniranta K, Koskela A, Felszeghy S, Kivinen N, Salminen A, Kauppinen A.

Biochimie. 2018 Jul 18. pii: S0300-9084(18)30205-0. doi: 10.1016/j.biochi.2018.07.010. [Epub ahead of print]

PMID:
30031036
12.

Myeloid-derived suppressor cells (MDSC): an important partner in cellular/tissue senescence.

Salminen A, Kauppinen A, Kaarniranta K.

Biogerontology. 2018 Oct;19(5):325-339. doi: 10.1007/s10522-018-9762-8. Epub 2018 Jun 29. Review.

PMID:
29959657
13.

Molecular Mechanisms Underlying Age-Related Ocular Diseases.

Amadio M, Kaarniranta K, Xu H, Smedowski A, Ferrington DA.

Oxid Med Cell Longev. 2018 May 21;2018:8476164. doi: 10.1155/2018/8476164. eCollection 2018. No abstract available.

14.

Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice.

Ruotsalainen AK, Lappalainen JP, Heiskanen E, Merentie M, Sihvola V, Näpänkangas J, Lottonen-Raikaslehto L, Kansanen E, Adinolfi S, Kaarniranta K, Ylä-Herttuala S, Jauhiainen M, Pirinen E, Levonen AL.

Cardiovasc Res. 2019 Jan 1;115(1):243-254. doi: 10.1093/cvr/cvy143.

PMID:
29917052
15.

Phytochemicals inhibit the immunosuppressive functions of myeloid-derived suppressor cells (MDSC): Impact on cancer and age-related chronic inflammatory disorders.

Salminen A, Kaarniranta K, Kauppinen A.

Int Immunopharmacol. 2018 Aug;61:231-240. doi: 10.1016/j.intimp.2018.06.005. Epub 2018 Jun 9. Review.

PMID:
29894862
16.

The potential importance of myeloid-derived suppressor cells (MDSCs) in the pathogenesis of Alzheimer's disease.

Salminen A, Kaarniranta K, Kauppinen A.

Cell Mol Life Sci. 2018 Sep;75(17):3099-3120. doi: 10.1007/s00018-018-2844-6. Epub 2018 May 19. Review.

PMID:
29779041
17.

Mitochondrial quality control in AMD: does mitophagy play a pivotal role?

Hyttinen JMT, Viiri J, Kaarniranta K, Błasiak J.

Cell Mol Life Sci. 2018 Aug;75(16):2991-3008. doi: 10.1007/s00018-018-2843-7. Epub 2018 May 18. Review.

PMID:
29777261
18.

Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome.

Piippo N, Korhonen E, Hytti M, Skottman H, Kinnunen K, Josifovska N, Petrovski G, Kaarniranta K, Kauppinen A.

Sci Rep. 2018 Apr 30;8(1):6720. doi: 10.1038/s41598-018-25123-2.

19.

Mechanistical retinal drug targets and challenges.

Kaarniranta K, Xu H, Kauppinen A.

Adv Drug Deliv Rev. 2018 Feb 15;126:177-184. doi: 10.1016/j.addr.2018.04.016. Epub 2018 Apr 23. Review.

PMID:
29698626
20.

Tear film proteome in age-related macular degeneration.

Winiarczyk M, Kaarniranta K, Winiarczyk S, Adaszek Ł, Winiarczyk D, Mackiewicz J.

Graefes Arch Clin Exp Ophthalmol. 2018 Jun;256(6):1127-1139. doi: 10.1007/s00417-018-3984-y. Epub 2018 Apr 25.

Supplemental Content

Loading ...
Support Center