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Items: 1 to 20 of 70


Activated carbon/Brønsted acid-promoted aerobic benzylic oxidation under "on-water" condition: Green and efficient synthesis of 3-benzoylquinoxalinones as potent tubulin inhibitors.

Guan Q, Cong L, Wang Q, Yu C, Bao K, Zhou K, Wu L, Zhang W.

Eur J Med Chem. 2019 Nov 19:111894. doi: 10.1016/j.ejmech.2019.111894. [Epub ahead of print]


Design, synthesis and bio-evaluation of novel 2-aryl-4-(3,4,5-trimethoxy-benzoyl)-5-substituted-1,2,3-triazoles as the tubulin polymerization inhibitors.

Huang L, Liu M, Man S, Ma D, Feng D, Sun Z, Guan Q, Zuo D, Wu Y, Zhang W, Bao K.

Eur J Med Chem. 2019 Nov 2:111846. doi: 10.1016/j.ejmech.2019.111846. [Epub ahead of print]


Virulence and Pathogenicity Properties of Aggregatibacter actinomycetemcomitans.

Belibasakis GN, Maula T, Bao K, Lindholm M, Bostanci N, Oscarsson J, Ihalin R, Johansson A.

Pathogens. 2019 Nov 6;8(4). pii: E222. doi: 10.3390/pathogens8040222. Review.


Targeted molecular imaging of TLR4 in hepatocellular carcinoma using zwitterionic near-infrared fluorophores.

Ji Y, Wang Z, Bao K, Park GK, Kang H, Hu S, McDonald E, Kim MS, Kashiwagi S, Choi HS.

Quant Imaging Med Surg. 2019 Sep;9(9):1548-1555. doi: 10.21037/qims.2019.09.04.


Periodontal disease: From the lenses of light microscopy to the specs of proteomics and next-generation sequencing.

Bostanci N, Bao K, Greenwood D, Silbereisen A, Belibasakis GN.

Adv Clin Chem. 2019;93:263-290. doi: 10.1016/bs.acc.2019.07.006. Epub 2019 Aug 30.


Prognostic imaging of iatrogenic and traumatic ureteral injury by near-infrared fluorescence.

Ahn CB, Kim JH, Park GK, Park KY, Bao K, Lee JW, Choi HS, Son KH.

Quant Imaging Med Surg. 2019 Jun;9(6):1056-1065. doi: 10.21037/qims.2019.06.15.


Design, synthesis and biological evaluation of 3,4-diaryl-1,2,5-oxadiazole-2/5-oxides as highly potent inhibitors of tubulin polymerization.

Hong Y, Zhao Y, Yang L, Gao M, Li L, Man S, Wang Z, Guan Q, Bao K, Zuo D, Wu Y, Zhang W.

Eur J Med Chem. 2019 Sep 15;178:287-296. doi: 10.1016/j.ejmech.2019.05.036. Epub 2019 May 14.


Free-standing porous Ni2P-Ni5P4 heterostructured arrays for efficient electrocatalytic water splitting.

Yan Y, Lin J, Bao K, Xu T, Qi J, Cao J, Zhong Z, Fei W, Feng J.

J Colloid Interface Sci. 2019 Sep 15;552:332-336. doi: 10.1016/j.jcis.2019.05.064. Epub 2019 May 21.


Synthesis and bioevaluation of diarylpyrazoles as antiproliferative agents.

Wang C, Yang S, Du J, Ni J, Wu Y, Wang J, Guan Q, Zuo D, Bao K, Wu Y, Zhang W.

Eur J Med Chem. 2019 Jun 1;171:1-10. doi: 10.1016/j.ejmech.2019.02.049. Epub 2019 Feb 18.


Design, synthesis and bioevaluation of 3-oxo-6-aryl-2,3-dihydropyridazine-4-carbohydrazide derivatives as novel xanthine oxidase inhibitors.

Zhang L, Wang S, Yang M, Shi A, Wang H, Guan Q, Bao K, Zhang W.

Bioorg Med Chem. 2019 May 1;27(9):1818-1823. doi: 10.1016/j.bmc.2019.03.027. Epub 2019 Mar 13.


3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation.

Zhai M, Liu S, Gao M, Wang L, Sun J, Du J, Guan Q, Bao K, Zuo D, Wu Y, Zhang W.

Eur J Med Chem. 2019 Apr 15;168:426-435. doi: 10.1016/j.ejmech.2018.12.053. Epub 2018 Dec 24.


Conformation impacts on the bioactivities of SMART analogues.

Wu Y, Guan Q, Zheng D, Yan P, Feng D, Du J, Zhang J, Zuo D, Bao K, Zhang W.

Eur J Med Chem. 2018 Oct 5;158:733-742. doi: 10.1016/j.ejmech.2018.09.045. Epub 2018 Sep 15.


Gingival Exudatome Dynamics Implicate Inhibition of the Alternative Complement Pathway in the Protective Action of the C3 Inhibitor Cp40 in Nonhuman Primate Periodontitis.

Bostanci N, Bao K, Li X, Maekawa T, Grossmann J, Panse C, Briones RA, Resuello RRG, Tuplano JV, Garcia CAG, Reis ES, Lambris JD, Hajishengallis G.

J Proteome Res. 2018 Sep 7;17(9):3153-3175. doi: 10.1021/acs.jproteome.8b00263. Epub 2018 Aug 29.


Synthesis and biological evaluation of (1-aryl-1H-pyrazol-4-yl) (3,4,5-trimethoxyphenyl)methanone derivatives as tubulin inhibitors.

Zhai M, Wang L, Liu S, Wang L, Yan P, Wang J, Zhang J, Guo H, Guan Q, Bao K, Wu Y, Zhang W.

Eur J Med Chem. 2018 Aug 5;156:137-147. doi: 10.1016/j.ejmech.2018.05.058. Epub 2018 Jun 2.


Multivalent Mannose-Decorated NIR Nanoprobes for Targeting Pan Lymph Nodes.

Wada H, Hyun H, Bao K, Lee JH, El Fakhri G, Choi Y, Choi HS.

Chem Eng J. 2018 May 15;340:51-57. doi: 10.1016/j.cej.2018.01.008. Epub 2018 Jan 3.


Design, synthesis and bioevaluation of 2-mercapto-6-phenylpyrimidine-4-carboxylic acid derivatives as potent xanthine oxidase inhibitors.

Shi A, Zhang L, Wang H, Wang S, Yang M, Guan Q, Bao K, Zhang W.

Eur J Med Chem. 2018 Jul 15;155:590-595. doi: 10.1016/j.ejmech.2018.06.009. Epub 2018 Jun 5.


Aggregatibacter actinomycetemcomitans H-NS promotes biofilm formation and alters protein dynamics of other species within a polymicrobial oral biofilm.

Bao K, Bostanci N, Thurnheer T, Grossmann J, Wolski WE, Thay B, Belibasakis GN, Oscarsson J.

NPJ Biofilms Microbiomes. 2018 May 22;4:12. doi: 10.1038/s41522-018-0055-4. eCollection 2018.


Targeted Proteomics Guided by Label-free Quantitative Proteome Analysis in Saliva Reveal Transition Signatures from Health to Periodontal Disease.

Bostanci N, Selevsek N, Wolski W, Grossmann J, Bao K, Wahlander A, Trachsel C, Schlapbach R, Öztürk VÖ, Afacan B, Emingil G, Belibasakis GN.

Mol Cell Proteomics. 2018 Jul;17(7):1392-1409. doi: 10.1074/mcp.RA118.000718. Epub 2018 Apr 2.


Design and synthesis of 5-aryl-4-(4-arylpiperazine-1-carbonyl)-2H-1,2,3-triazole derivatives as colchicine binding site inhibitors.

Wu Y, Feng D, Gao M, Wang Z, Yan P, Gu Z, Guan Q, Zuo D, Bao K, Sun J, Wu Y, Zhang W.

Sci Rep. 2017 Dec 7;7(1):17120. doi: 10.1038/s41598-017-17449-0.


Bioimaging of botulinum toxin and hyaluronate hydrogels using zwitterionic near-infrared fluorophores.

Kim KS, Kim YS, Bao K, Wada H, Choi HS, Hahn SK.

Biomater Res. 2017 Oct 10;21:15. doi: 10.1186/s40824-017-0102-x. eCollection 2017.

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