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Items: 1 to 20 of 61

1.

An omics perspective on drug target discovery platforms.

Paananen J, Fortino V.

Brief Bioinform. 2019 Nov 27. pii: bbz122. doi: 10.1093/bib/bbz122. [Epub ahead of print]

PMID:
31774113
2.

The Contribution of Staffing to Medication Administration Errors: A Text Mining Analysis of Incident Report Data.

Härkänen M, Vehviläinen-Julkunen K, Murrells T, Paananen J, Franklin BD, Rafferty AM.

J Nurs Scholarsh. 2019 Nov 25. doi: 10.1111/jnu.12531. [Epub ahead of print]

PMID:
31763763
3.

Identifying risks areas related to medication administrations - text mining analysis using free-text descriptions of incident reports.

Härkänen M, Paananen J, Murrells T, Rafferty AM, Franklin BD.

BMC Health Serv Res. 2019 Nov 4;19(1):791. doi: 10.1186/s12913-019-4597-9.

4.

In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury-Lessons Learned.

Lipponen A, Natunen T, Hujo M, Ciszek R, Hämäläinen E, Tohka J, Hiltunen M, Paananen J, Poulsen D, Kansanen E, Ekolle Ndode-Ekane X, Levonen AL, Pitkänen A.

Int J Mol Sci. 2019 Oct 29;20(21). pii: E5395. doi: 10.3390/ijms20215395.

5.

Random forest-based imputation outperforms other methods for imputing LC-MS metabolomics data: a comparative study.

Kokla M, Virtanen J, Kolehmainen M, Paananen J, Hanhineva K.

BMC Bioinformatics. 2019 Oct 11;20(1):492. doi: 10.1186/s12859-019-3110-0.

6.

Prioritizing target-disease associations with novel safety and efficacy scoring methods.

Failli M, Paananen J, Fortino V.

Sci Rep. 2019 Jul 8;9(1):9852. doi: 10.1038/s41598-019-46293-7.

7.

Active eukaryotes in drinking water distribution systems of ground and surface waterworks.

Inkinen J, Jayaprakash B, Siponen S, Hokajärvi AM, Pursiainen A, Ikonen J, Ryzhikov I, Täubel M, Kauppinen A, Paananen J, Miettinen IT, Torvinen E, Kolehmainen M, Pitkänen T.

Microbiome. 2019 Jul 3;7(1):99. doi: 10.1186/s40168-019-0715-5.

8.

Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with Metabolic Syndrome-A SYSDIET Sub-Study.

Myhrstad MCW, de Mello VD, Dahlman I, Kolehmainen M, Paananen J, Rundblad A, Carlberg C, Olstad OK, Pihlajamäki J, Holven KB, Hermansen K, Dragsted LO, Gunnarsdottir I, Cloetens L, Storm MU, Åkesson B, Rosqvist F, Hukkanen J, Herzig KH, Risérus U, Thorsdottir I, Poutanen KS, Savolainen MJ, Schwab U, Arner P, Uusitupa M, Ulven SM.

Mol Nutr Food Res. 2019 Apr 9:e1801405. doi: 10.1002/mnfr.201801405. [Epub ahead of print]

PMID:
30964598
9.

Text Mining Method for Studying Medication Administration Incidents and Nurse-Staffing Contributing Factors: A Pilot Study.

Härkänen M, Vehviläinen-Julkunen K, Murrells T, Paananen J, Rafferty AM.

Comput Inform Nurs. 2019 Jul;37(7):357-365. doi: 10.1097/CIN.0000000000000518.

PMID:
30870188
10.

Digitally supported program for type 2 diabetes risk identification and risk reduction in real-world setting: protocol for the StopDia model and randomized controlled trial.

Pihlajamäki J, Männikkö R, Tilles-Tirkkonen T, Karhunen L, Kolehmainen M, Schwab U, Lintu N, Paananen J, Järvenpää R, Harjumaa M, Martikainen J, Kohl J, Poutanen K, Ermes M, Absetz P, Lindström J, Lakka TA; StopDia study group.

BMC Public Health. 2019 Mar 1;19(1):255. doi: 10.1186/s12889-019-6574-y.

11.

Varanto: variant enrichment analysis and annotation.

Timonen O, Särkkä M, Fülöp T, Mattsson A, Kekäläinen J, Paananen J.

Bioinformatics. 2019 Sep 1;35(17):3154-3156. doi: 10.1093/bioinformatics/btz046.

PMID:
30689722
12.

A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology.

Marttinen M, Paananen J, Neme A, Mitra V, Takalo M, Natunen T, Paldanius KMA, Mäkinen P, Bremang M, Kurki MI, Rauramaa T, Leinonen V, Soininen H, Haapasalo A, Pike I, Hiltunen M.

Neurobiol Dis. 2019 Apr;124:454-468. doi: 10.1016/j.nbd.2018.12.009. Epub 2018 Dec 15.

13.

Metabolic Profiling of High Egg Consumption and the Associated Lower Risk of Type 2 Diabetes in Middle-Aged Finnish Men.

Noerman S, Kärkkäinen O, Mattsson A, Paananen J, Lehtonen M, Nurmi T, Tuomainen TP, Voutilainen S, Hanhineva K, Virtanen JK.

Mol Nutr Food Res. 2019 Mar;63(5):e1800605. doi: 10.1002/mnfr.201800605. Epub 2018 Dec 18.

PMID:
30548819
14.

Kuopio birth cohort - design of a Finnish joint research effort for identification of environmental and lifestyle risk factors for the wellbeing of the mother and the newborn child.

Huuskonen P, Keski-Nisula L, Heinonen S, Voutilainen S, Tuomainen TP, Pekkanen J, Lampi J, Lehto SM, Haaparanta H, Elomaa AP, Voutilainen R, Backman K, Kokki H, Kumpulainen K, Paananen J, Vähäkangas K, Pasanen M.

BMC Pregnancy Childbirth. 2018 Sep 21;18(1):381. doi: 10.1186/s12884-018-2013-9.

15.

Associations of Genetic Susceptibility to Alzheimer's Disease with Adiposity and Cardiometabolic Risk Factors among Children in a 2-Year Follow-up Study.

Haapala EA, Paananen J, Hiltunen M, Lakka TA.

J Alzheimers Dis. 2018;64(2):587-595. doi: 10.3233/JAD-180216.

PMID:
29914036
16.

Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury.

Lipponen A, El-Osta A, Kaspi A, Ziemann M, Khurana I, Kn H, Navarro-Ferrandis V, Puhakka N, Paananen J, Pitkänen A.

Acta Neuropathol Commun. 2018 Feb 27;6(1):17. doi: 10.1186/s40478-018-0519-z.

17.

Interrelationship between the Levels of C9orf72 and Amyloid-β Protein Precursor and Amyloid-β in Human Cells and Brain Samples.

Leskelä S, Takalo M, Marttinen M, Huber N, Paananen J, Mitra V, Rauramaa T, Mäkinen P, Leinonen V, Soininen H, Pike I, Remes AM, Hiltunen M, Haapasalo A.

J Alzheimers Dis. 2018;62(1):269-278. doi: 10.3233/JAD-170362.

PMID:
29439323
18.

Fetal Microsatellite in the Heme Oxygenase 1 Promoter Is Associated With Severe and Early-Onset Preeclampsia.

Kaartokallio T, Utge S, Klemetti MM, Paananen J, Pulkki K, Romppanen J, Tikkanen I, Heinonen S, Kajantie E, Kere J, Kivinen K, Pouta A, Lakkisto P, Laivuori H.

Hypertension. 2018 Jan;71(1):95-102. doi: 10.1161/HYPERTENSIONAHA.117.10425. Epub 2017 Dec 4.

PMID:
29203625
19.

Alzheimer's Disease-Related Polymorphisms in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus.

Huovinen J, Helisalmi S, Paananen J, Laiterä T, Kojoukhova M, Sutela A, Vanninen R, Laitinen M, Rauramaa T, Koivisto AM, Remes AM, Soininen H, Kurki M, Haapasalo A, Jääskeläinen JE, Hiltunen M, Leinonen V.

J Alzheimers Dis. 2017;60(3):1077-1085. doi: 10.3233/JAD-170583.

PMID:
28984604
20.

Screening approach for identifying candidate drugs and drug-drug interactions related to hip fracture risk in persons with Alzheimer disease.

Tolppanen AM, Taipale H, Koponen M, Tanskanen A, Lavikainen P, Paananen J, Tiihonen J, Hartikainen S.

Pharmacoepidemiol Drug Saf. 2017 Aug;26(8):875-889. doi: 10.1002/pds.4232. Epub 2017 May 29.

PMID:
28556303

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