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Chem Commun (Camb). 2019 Aug 25;55(66):9857-9860. doi: 10.1039/c9cc05387e. Epub 2019 Jul 31.

A three-dimensional DNA walker amplified FRET sensor for detection of telomerase activity based on the MnO2 nanosheet-upconversion nanoparticle sensing platform.

Author information

1
College of Ecological Environment and Urban Construction, Fujian University of Technology, Fuzhou 350108, P. R. China.
2
Department of Pharmaceutical Analysis, The Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, School of Pharmacy, Fujian Medical University, Fuzhou 350122, China. Junyang.Zhuang@hotmail.com.
3
Key Laboratory of Analysis and Detection for Food Safety (Ministry of Education & Fujian Province), Institute of Nanomedicine and Nanobiosensing, Department of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China. dianping.tang@fzu.edu.cn.

Abstract

A novel fluorescent sensing platform for telomerase activity assay was developed by coupling a three-dimensional (3D) DNA walker with the MnO2 nanosheet-upconversion nanoparticle (UCNPs) complex-based fluorescence resonance energy-transfer (FRET) system.

PMID:
31364637
DOI:
10.1039/c9cc05387e
[Indexed for MEDLINE]

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