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Items: 1 to 20 of 24


Transcriptionally elevation of miR-494 by new ChlA-F compound via a HuR/JunB axis inhibits human bladder cancer cell invasion.

Tian Z, Luo Y, Zhu J, Hua X, Xu J, Huang C, Jin H, Huang H, Huang C.

Biochim Biophys Acta Gene Regul Mech. 2019 Jun 2. pii: S1874-9399(19)30018-5. doi: 10.1016/j.bbagrm.2019.05.007. [Epub ahead of print]


MicroRNA-146b Overexpression Promotes Human Bladder Cancer Invasion via Enhancing ETS2-Mediated mmp2 mRNA Transcription.

Zhu J, Xu C, Ruan L, Wu J, Li Y, Zhang X.

Mol Ther Nucleic Acids. 2019 Jun 7;16:531-542. doi: 10.1016/j.omtn.2019.04.007. Epub 2019 Apr 14.


ATG7 Promotes Bladder Cancer Invasion via Autophagy-Mediated Increased ARHGDIB mRNA Stability.

Zhu J, Tian Z, Li Y, Hua X, Zhang D, Li J, Jin H, Xu J, Chen W, Niu B, Wu XR, Comincini S, Huang H, Huang C.

Adv Sci (Weinh). 2019 Feb 22;6(8):1801927. doi: 10.1002/advs.201801927. eCollection 2019 Apr 17.


A Feedback Loop Formed by ATG7/Autophagy, FOXO3a/miR-145 and PD-L1 Regulates Stem-Like Properties and Invasion in Human Bladder Cancer.

Zhu J, Li Y, Luo Y, Xu J, Liufu H, Tian Z, Huang C, Li J, Huang C.

Cancers (Basel). 2019 Mar 12;11(3). pii: E349. doi: 10.3390/cancers11030349.


CD44s is a crucial ATG7 downstream regulator for stem-like property, invasion, and lung metastasis of human bladder cancer (BC) cells.

Zhu J, Huang G, Hua X, Li Y, Yan H, Che X, Tian Z, Liufu H, Huang C, Li J, Xu J, Dai W, Huang H, Huang C.

Oncogene. 2019 Apr;38(17):3301-3315. doi: 10.1038/s41388-018-0664-7. Epub 2019 Jan 11.


NFκB2 p52 stabilizes rhogdiβ mRNA by inhibiting AUF1 protein degradation via a miR-145/Sp1/USP8-dependent axis.

Xu J, Hua X, Jin H, Zhu J, Li Y, Li J, Huang C.

Mol Carcinog. 2019 May;58(5):777-793. doi: 10.1002/mc.22970. Epub 2019 Jan 29.


New compound ChlA-F induces autophagy-dependent anti-cancer effect via upregulating Sestrin-2 in human bladder cancer.

Hua X, Xu J, Deng X, Xu J, Li J, Zhu DQ, Zhu J, Jin H, Tian Z, Huang H, Zhao QS, Huang C.

Cancer Lett. 2018 Nov 1;436:38-51. doi: 10.1016/j.canlet.2018.08.013. Epub 2018 Aug 16.


Decreased c-Myc mRNA Stability via the MicroRNA 141-3p/AUF1 Axis Is Crucial for p63α Inhibition of Cyclin D1 Gene Transcription and Bladder Cancer Cell Tumorigenicity.

Li X, Tian Z, Jin H, Xu J, Hua X, Yan H, Liufu H, Wang J, Li J, Zhu J, Huang H, Huang C.

Mol Cell Biol. 2018 Oct 15;38(21). pii: e00273-18. doi: 10.1128/MCB.00273-18. Print 2018 Nov 1.


Transcriptional and post-transcriptional upregulation of p27 mediates growth inhibition of isorhapontigenin (ISO) on human bladder cancer cells.

Jiang G, Huang C, Li J, Huang H, Wang J, Li Y, Xie F, Jin H, Zhu J, Huang C.

Carcinogenesis. 2018 Mar 8;39(3):482-492. doi: 10.1093/carcin/bgy015.


RhoGDIβ promotes Sp1/MMP-2 expression and bladder cancer invasion through perturbing miR-200c-targeted JNK2 protein translation.

Huang H, Jin H, Zhao H, Wang J, Li X, Yan H, Wang S, Guo X, Xue L, Li J, Peng M, Wang A, Zhu J, Wu XR, Chen C, Huang C.

Mol Oncol. 2017 Nov;11(11):1579-1594. doi: 10.1002/1878-0261.12132. Epub 2017 Sep 11.


p63α protein up-regulates heat shock protein 70 expression via E2F1 transcription factor 1, promoting Wasf3/Wave3/MMP9 signaling and bladder cancer invasion.

Jin H, Xie Q, Guo X, Xu J, Wang A, Li J, Zhu J, Wu XR, Huang H, Huang C.

J Biol Chem. 2017 Sep 22;292(38):15952-15963. doi: 10.1074/jbc.M117.792010. Epub 2017 Aug 9.


NF-κB p65 Overexpression Promotes Bladder Cancer Cell Migration via FBW7-Mediated Degradation of RhoGDIα Protein.

Zhu J, Li Y, Chen C, Ma J, Sun W, Tian Z, Li J, Xu J, Liu CS, Zhang D, Huang C, Huang H.

Neoplasia. 2017 Sep;19(9):672-683. doi: 10.1016/j.neo.2017.06.002. Epub 2017 Aug 1.


ATG7 Overexpression Is Crucial for Tumorigenic Growth of Bladder Cancer In Vitro and In Vivo by Targeting the ETS2/miRNA196b/FOXO1/p27 Axis.

Zhu J, Li Y, Tian Z, Hua X, Gu J, Li J, Liu C, Jin H, Wang Y, Jiang G, Huang H, Huang C.

Mol Ther Nucleic Acids. 2017 Jun 16;7:299-313. doi: 10.1016/j.omtn.2017.04.012. Epub 2017 Apr 14.


Role of STAT3 and FOXO1 in the Divergent Therapeutic Responses of Non-metastatic and Metastatic Bladder Cancer Cells to miR-145.

Jiang G, Huang C, Li J, Huang H, Jin H, Zhu J, Wu XR, Huang C.

Mol Cancer Ther. 2017 May;16(5):924-935. doi: 10.1158/1535-7163.MCT-16-0631. Epub 2017 Feb 21.


XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell.

Huang C, Zeng X, Jiang G, Liao X, Liu C, Li J, Jin H, Zhu J, Sun H, Wu XR, Huang C.

J Hematol Oncol. 2017 Jan 5;10(1):6. doi: 10.1186/s13045-016-0376-9.


A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis.

Yue X, Zhao Y, Huang G, Li J, Zhu J, Feng Z, Hu W.

Cell Discov. 2016 Nov 1;2:16039. eCollection 2016.


Cullin3-KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression.

Zhang C, Liu J, Huang G, Zhao Y, Yue X, Wu H, Li J, Zhu J, Shen Z, Haffty BG, Hu W, Feng Z.

Genes Dev. 2016 Sep 1;30(17):1956-70. doi: 10.1101/gad.283283.116.


Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation.

Zhang R, Che X, Zhang J, Li Y, Li J, Deng X, Zhu J, Jin H, Zhao Q, Huang C.

Oncotarget. 2016 Oct 11;7(41):66689-66699. doi: 10.18632/oncotarget.11440.


Upregulation of SQSTM1/p62 contributes to nickel-induced malignant transformation of human bronchial epithelial cells.

Huang H, Zhu J, Li Y, Zhang L, Gu J, Xie Q, Jin H, Che X, Li J, Huang C, Chen LC, Lyu J, Gao J, Huang C.

Autophagy. 2016 Oct 2;12(10):1687-1703. Epub 2016 Jul 28.


XIAP RING domain mediates miR-4295 expression and subsequently inhibiting p63α protein translation and promoting transformation of bladder epithelial cells.

Jin H, Xu J, Guo X, Huang H, Li J, Peng M, Zhu J, Tian Z, Wu XR, Tang MS, Huang C.

Oncotarget. 2016 Aug 30;7(35):56540-56557. doi: 10.18632/oncotarget.10645.

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