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Items: 1 to 20 of 38


Tanshinone IIA reduces palmitate-induced apoptosis via inhibition of endoplasmic reticulum stress in HepG2 liver cells.

Wang J, Hu R, Yin C, Xiao Y.

Fundam Clin Pharmacol. 2019 Sep 14. doi: 10.1111/fcp.12510. [Epub ahead of print]


Chrysophanol protects against doxorubicin-induced cardiotoxicity by suppressing cellular PARylation.

Lu J, Li J, Hu Y, Guo Z, Sun D, Wang P, Guo K, Duan DD, Gao S, Jiang J, Wang J, Liu P.

Acta Pharm Sin B. 2019 Jul;9(4):782-793. doi: 10.1016/j.apsb.2018.10.008. Epub 2018 Nov 1.


New Alkaloids and Polyketides from the Marine Sponge-Derived Fungus Penicillium sp. SCSIO41015.

Pang X, Cai G, Lin X, Salendra L, Zhou X, Yang B, Wang J, Wang J, Xu S, Liu Y.

Mar Drugs. 2019 Jul 5;17(7). pii: E398. doi: 10.3390/md17070398.


SESN2 protects against doxorubicin-induced cardiomyopathy via rescuing mitophagy and improving mitochondrial function.

Wang P, Wang L, Lu J, Hu Y, Wang Q, Li Z, Cai S, Liang L, Guo K, Xie J, Wang J, Lan R, Shen J, Liu P.

J Mol Cell Cardiol. 2019 Aug;133:125-137. doi: 10.1016/j.yjmcc.2019.06.005. Epub 2019 Jun 12.


Nonlinearity of root trait relationships and the root economics spectrum.

Kong D, Wang J, Wu H, Valverde-Barrantes OJ, Wang R, Zeng H, Kardol P, Zhang H, Feng Y.

Nat Commun. 2019 May 17;10(1):2203. doi: 10.1038/s41467-019-10245-6.


Chrysophanol attenuated isoproterenol-induced cardiac hypertrophy by inhibiting Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway.

Yuan J, Hong H, Zhang Y, Lu J, Yu Y, Bi X, Wang J, Ye J.

Cell Biol Int. 2019 Jun;43(6):695-705. doi: 10.1002/cbin.11146. Epub 2019 Apr 29.


Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer.

Zhang Y, Wu X, Xue X, Li C, Wang J, Wang R, Zhang C, Wang C, Shi Y, Zou L, Li Q, Huang Z, Hao X, Loomes K, Wu D, Chen HW, Xu J, Xu Y.

J Med Chem. 2019 May 9;62(9):4716-4730. doi: 10.1021/acs.jmedchem.9b00327. Epub 2019 Apr 22.


Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors.

Xing J, Zhang R, Jiang X, Hu T, Wang X, Qiao G, Wang J, Yang F, Luo X, Chen K, Shen J, Luo C, Jiang H, Zheng M.

Eur J Med Chem. 2019 Feb 1;163:281-294. doi: 10.1016/j.ejmech.2018.11.018. Epub 2018 Nov 16.


sFRP1 has a biphasic effect on doxorubicin-induced cardiotoxicity in a cellular location-dependent manner in NRCMs and Rats.

Hu Y, Guo Z, Lu J, Wang P, Sun S, Zhang Y, Li J, Zheng Q, Guo K, Wang J, Jiang J, Liu P.

Arch Toxicol. 2019 Feb;93(2):533-546. doi: 10.1007/s00204-018-2342-5. Epub 2018 Oct 30.


Rhizosheaths stimulate short-term root decomposition in a semiarid grassland.

Kong D, Wang J, Yang F, Shao P.

Sci Total Environ. 2018 Nov 1;640-641:1297-1301. doi: 10.1016/j.scitotenv.2018.05.398. Epub 2018 Jun 7.


Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer.

Xue X, Zhang Y, Wang C, Zhang M, Xiang Q, Wang J, Wang A, Li C, Zhang C, Zou L, Wang R, Wu S, Lu Y, Chen H, Ding K, Li G, Xu Y.

Eur J Med Chem. 2018 May 25;152:542-559. doi: 10.1016/j.ejmech.2018.04.034. Epub 2018 Apr 21.


JMJD3 inhibition protects against isoproterenol-induced cardiac hypertrophy by suppressing β-MHC expression.

Guo Z, Lu J, Li J, Wang P, Li Z, Zhong Y, Guo K, Wang J, Ye J, Liu P.

Mol Cell Endocrinol. 2018 Dec 5;477:1-14. doi: 10.1016/j.mce.2018.05.009. Epub 2018 May 10.


MicroRNA-616 promotes the progression of ovarian cancer by targeting TIMP2.

Chen Z, Zhu J, Zhu Y, Wang J.

Oncol Rep. 2018 Jun;39(6):2960-2968. doi: 10.3892/or.2018.6368. Epub 2018 Apr 12.


Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC).

Zhang M, Zhang Y, Song M, Xue X, Wang J, Wang C, Zhang C, Li C, Xiang Q, Zou L, Wu X, Wu C, Dong B, Xue W, Zhou Y, Chen H, Wu D, Ding K, Xu Y.

J Med Chem. 2018 Apr 12;61(7):3037-3058. doi: 10.1021/acs.jmedchem.8b00103. Epub 2018 Apr 3.


Fisetin inhibits the growth and migration in the A549 human lung cancer cell line via the ERK1/2 pathway.

Wang J, Huang S.

Exp Ther Med. 2018 Mar;15(3):2667-2673. doi: 10.3892/etm.2017.5666. Epub 2017 Dec 21.


The nutrient absorption-transportation hypothesis: optimizing structural traits in absorptive roots.

Kong D, Wang J, Zeng H, Liu M, Miao Y, Wu H, Kardol P.

New Phytol. 2017 Mar;213(4):1569-1572. doi: 10.1111/nph.14344. Epub 2016 Nov 15. No abstract available.


Ossotide promotes cell differentiation of human osteoblasts from osteogenesis imperfecta patients by up-regulating miR-145.

Sun K, Wang J, Liu F, Ji Z, Guo Z, Zhang C, Yao M.

Biomed Pharmacother. 2016 Oct;83:1105-1110. doi: 10.1016/j.biopha.2016.08.025. Epub 2016 Aug 20.


Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy.

Wang J, Wang H, Wang LY, Cai D, Duan Z, Zhang Y, Chen P, Zou JX, Xu J, Chen X, Kung HJ, Chen HW.

Cell Death Differ. 2016 Nov 1;23(11):1886-1896. doi: 10.1038/cdd.2016.92. Epub 2016 Sep 9.


KDM4A Coactivates E2F1 to Regulate the PDK-Dependent Metabolic Switch between Mitochondrial Oxidation and Glycolysis.

Wang LY, Hung CL, Chen YR, Yang JC, Wang J, Campbell M, Izumiya Y, Chen HW, Wang WC, Ann DK, Kung HJ.

Cell Rep. 2016 Sep 13;16(11):3016-3027. doi: 10.1016/j.celrep.2016.08.018.


The effect of mechanical stretch stress on the differentiation and apoptosis of human growth plate chondrocytes.

Sun K, Liu F, Wang J, Guo Z, Ji Z, Yao M.

In Vitro Cell Dev Biol Anim. 2017 Feb;53(2):141-148. doi: 10.1007/s11626-016-0090-5. Epub 2016 Sep 7.


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