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Items: 1 to 20 of 94

1.

Single-cell study of neural stem cells derived from human iPSCs reveals distinct progenitor populations with neurogenic and gliogenic potential.

Lam M, Sanosaka T, Lundin A, Imaizumi K, Etal D, Karlsson FH, Clausen M, Cairns J, Hicks R, Kohyama J, Kele M, Okano H, Falk A.

Genes Cells. 2019 Dec;24(12):836-847. doi: 10.1111/gtc.12731. Epub 2019 Nov 17.

2.

The adeno-associated virus rh10 vector is an effective gene transfer system for chronic spinal cord injury.

Hoshino Y, Nishide K, Nagoshi N, Shibata S, Moritoki N, Kojima K, Tsuji O, Matsumoto M, Kohyama J, Nakamura M, Okano H.

Sci Rep. 2019 Jul 8;9(1):9844. doi: 10.1038/s41598-019-46069-z.

3.

Non-Cell-Autonomous Neurotoxicity in Parkinson's Disease Mediated by Astroglial α-Synuclein.

Chai M, Kohyama J.

Stem Cell Reports. 2019 Feb 12;12(2):183-185. doi: 10.1016/j.stemcr.2019.01.011.

4.

Loss of TET proteins in regulatory T cells promotes abnormal proliferation, Foxp3 destabilization and IL-17 expression.

Nakatsukasa H, Oda M, Yin J, Chikuma S, Ito M, Koga-Iizuka M, Someya K, Kitagawa Y, Ohkura N, Sakaguchi S, Koya I, Sanosaka T, Kohyama J, Tsukada YI, Yamanaka S, Takamura-Enya T, Lu Q, Yoshimura A.

Int Immunol. 2019 Apr 26;31(5):335-347. doi: 10.1093/intimm/dxz008.

PMID:
30726915
5.

Treatment with a Gamma-Secretase Inhibitor Promotes Functional Recovery in Human iPSC- Derived Transplants for Chronic Spinal Cord Injury.

Okubo T, Nagoshi N, Kohyama J, Tsuji O, Shinozaki M, Shibata S, Kase Y, Matsumoto M, Nakamura M, Okano H.

Stem Cell Reports. 2018 Dec 11;11(6):1416-1432. doi: 10.1016/j.stemcr.2018.10.022. Epub 2018 Nov 29.

6.

Selective Ablation of Tumorigenic Cells Following Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in Spinal Cord Injury.

Kojima K, Miyoshi H, Nagoshi N, Kohyama J, Itakura G, Kawabata S, Ozaki M, Iida T, Sugai K, Ito S, Fukuzawa R, Yasutake K, Renault-Mihara F, Shibata S, Matsumoto M, Nakamura M, Okano H.

Stem Cells Transl Med. 2019 Mar;8(3):260-270. doi: 10.1002/sctm.18-0096. Epub 2018 Nov 28.

7.

Concise Review: Laying the Groundwork for a First-In-Human Study of an Induced Pluripotent Stem Cell-Based Intervention for Spinal Cord Injury.

Tsuji O, Sugai K, Yamaguchi R, Tashiro S, Nagoshi N, Kohyama J, Iida T, Ohkubo T, Itakura G, Isoda M, Shinozaki M, Fujiyoshi K, Kanemura Y, Yamanaka S, Nakamura M, Okano H.

Stem Cells. 2019 Jan;37(1):6-13. doi: 10.1002/stem.2926. Epub 2018 Nov 12. Review.

8.

T-type Calcium Channels Determine the Vulnerability of Dopaminergic Neurons to Mitochondrial Stress in Familial Parkinson Disease.

Tabata Y, Imaizumi Y, Sugawara M, Andoh-Noda T, Banno S, Chai M, Sone T, Yamazaki K, Ito M, Tsukahara K, Saya H, Hattori N, Kohyama J, Okano H.

Stem Cell Reports. 2018 Nov 13;11(5):1171-1184. doi: 10.1016/j.stemcr.2018.09.006. Epub 2018 Oct 18.

9.

Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors.

Chai M, Sanosaka T, Okuno H, Zhou Z, Koya I, Banno S, Andoh-Noda T, Tabata Y, Shimamura R, Hayashi T, Ebisawa M, Sasagawa Y, Nikaido I, Okano H, Kohyama J.

Genes Dev. 2018 Jan 15;32(2):165-180. doi: 10.1101/gad.301887.117. Epub 2018 Feb 9.

10.

Insufficient sleep syndrome: An unrecognized but important clinical entity.

Kohyama J, Anzai Y, Ono M, Kishino A, Tamanuki K, Takada K, Inoue K, Horiuchi M, Hatai Y.

Pediatr Int. 2018 Apr;60(4):372-375. doi: 10.1111/ped.13519. Epub 2018 Feb 28.

PMID:
29337407
11.

CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations.

Okuno H, Renault Mihara F, Ohta S, Fukuda K, Kurosawa K, Akamatsu W, Sanosaka T, Kohyama J, Hayashi K, Nakajima K, Takahashi T, Wysocka J, Kosaki K, Okano H.

Elife. 2017 Nov 28;6. pii: e21114. doi: 10.7554/eLife.21114.

12.

Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation.

Someya K, Nakatsukasa H, Ito M, Kondo T, Tateda KI, Akanuma T, Koya I, Sanosaka T, Kohyama J, Tsukada YI, Takamura-Enya T, Yoshimura A.

Int Immunol. 2017 Aug 1;29(8):365-375. doi: 10.1093/intimm/dxx049.

13.

Low immunogenicity of mouse induced pluripotent stem cell-derived neural stem/progenitor cells.

Itakura G, Ozaki M, Nagoshi N, Kawabata S, Nishiyama Y, Sugai K, Iida T, Kashiwagi R, Ookubo T, Yastake K, Matsubayashi K, Kohyama J, Iwanami A, Matsumoto M, Nakamura M, Okano H.

Sci Rep. 2017 Oct 11;7(1):12996. doi: 10.1038/s41598-017-13522-w.

14.

Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives.

Itakura G, Kawabata S, Ando M, Nishiyama Y, Sugai K, Ozaki M, Iida T, Ookubo T, Kojima K, Kashiwagi R, Yasutake K, Nakauchi H, Miyoshi H, Nagoshi N, Kohyama J, Iwanami A, Matsumoto M, Nakamura M, Okano H.

Stem Cell Reports. 2017 Mar 14;8(3):673-684. doi: 10.1016/j.stemcr.2017.02.003. Epub 2017 Mar 2.

15.

Whole-Genome DNA Methylation Analyses Revealed Epigenetic Instability in Tumorigenic Human iPS Cell-Derived Neural Stem/Progenitor Cells.

Iida T, Iwanami A, Sanosaka T, Kohyama J, Miyoshi H, Nagoshi N, Kashiwagi R, Toyama Y, Matsumoto M, Nakamura M, Okano H.

Stem Cells. 2017 May;35(5):1316-1327. doi: 10.1002/stem.2581. Epub 2017 Feb 23.

16.

Functional Comparison of Neuronal Cells Differentiated from Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells under Different Oxygen and Medium Conditions.

Yamazaki K, Fukushima K, Sugawara M, Tabata Y, Imaizumi Y, Ishihara Y, Ito M, Tsukahara K, Kohyama J, Okano H.

J Biomol Screen. 2016 Dec;21(10):1054-1064. doi: 10.1177/1087057116661291. Epub 2016 Aug 19.

PMID:
28139961
17.

Evaluation of the immunogenicity of human iPS cell-derived neural stem/progenitor cells in vitro.

Ozaki M, Iwanami A, Nagoshi N, Kohyama J, Itakura G, Iwai H, Nishimura S, Nishiyama Y, Kawabata S, Sugai K, Iida T, Matsubayashi K, Isoda M, Kashiwagi R, Toyama Y, Matsumoto M, Okano H, Nakamura M.

Stem Cell Res. 2017 Mar;19:128-138. doi: 10.1016/j.scr.2017.01.007. Epub 2017 Jan 19.

18.

Good daily habits during the early stages of life determine success throughout life.

Kohyama J.

Sleep Sci. 2016 Jul-Sep;9(3):153-157. doi: 10.1016/j.slsci.2016.09.002. Epub 2016 Oct 5. Review.

19.

Changeability of the fully methylated status of the 15q11.2 region in induced pluripotent stem cells derived from a patient with Prader-Willi syndrome.

Okuno H, Nakabayashi K, Abe K, Ando T, Sanosaka T, Kohyama J, Akamatsu W, Ohyama M, Takahashi T, Kosaki K, Okano H.

Congenit Anom (Kyoto). 2017 Jul;57(4):96-103. doi: 10.1111/cga.12206. Epub 2017 Mar 22.

PMID:
28004416
20.

Possible neuronal mechanisms of sleep disturbances in patients with autism spectrum disorders and attention-deficit/hyperactivity disorder.

Kohyama J.

Med Hypotheses. 2016 Dec;97:131-133. doi: 10.1016/j.mehy.2016.11.001. Epub 2016 Nov 5.

PMID:
27876121

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