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Items: 1 to 20 of 95

1.

The GLP1R Agonist Liraglutide Reduces Hyperglucagonemia Induced by the SGLT2 Inhibitor Dapagliflozin via Somatostatin Release.

Saponaro C, Gmyr V, Thévenet J, Moerman E, Delalleau N, Pasquetti G, Coddeville A, Quenon A, Daoudi M, Hubert T, Vantyghem MC, Bousquet C, Martineau Y, Kerr-Conte J, Staels B, Pattou F, Bonner C.

Cell Rep. 2019 Aug 6;28(6):1447-1454.e4. doi: 10.1016/j.celrep.2019.07.009.

2.

The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward.

Ndiaye FK, Huyvaert M, Ortalli A, Canouil M, Lecoeur C, Verbanck M, Lobbens S, Khamis A, Marselli L, Marchetti P, Kerr-Conte J, Pattou F, Marre M, Roussel R, Balkau B, Froguel P, Bonnefond A.

Int J Obes (Lond). 2019 Aug 6. doi: 10.1038/s41366-019-0428-7. [Epub ahead of print]

PMID:
31388097
3.

Heterogeneity of human pancreatic islet isolation around Europe: results of a survey study.

Nano R, Kerr-Conte JA, Scholz H, Engelse M, Karlsson M, Saudek F, Bosco D, Antonioli B, Bertuzzi F, Johnson PRV, Ludwing B, Ling Z, De Paep DL, Keymeulen B, Pattou F, Berney T, Korsgren O, de Koning E, Piemonti L.

Transplantation. 2019 Jul 17. doi: 10.1097/TP.0000000000002777. [Epub ahead of print]

PMID:
31365472
4.

Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes.

Pasquier A, Vivot K, Erbs E, Spiegelhalter C, Zhang Z, Aubert V, Liu Z, Senkara M, Maillard E, Pinget M, Kerr-Conte J, Pattou F, Marciniak G, Ganzhorn A, Ronchi P, Schieber NL, Schwab Y, Saftig P, Goginashvili A, Ricci R.

Nat Commun. 2019 Jul 25;10(1):3312. doi: 10.1038/s41467-019-11170-4.

5.

Islets for Research: Nothing Is Perfect, but We Can Do Better.

Nano R, Kerr-Conte JA, Bosco D, Karlsson M, Lavallard V, Melzi R, Gmyr V, Mercalli A, Berney T, Pattou F, Korsgren O, Piemonti L.

Diabetes. 2019 Aug;68(8):1541-1543. doi: 10.2337/db19-0367.

PMID:
31331988
6.

Coxsackievirus-B4 Infection of Human Primary Pancreatic Ductal Cell Cultures Results in Impairment of Differentiation into Insulin-Producing Cells.

Bertin A, Sane F, Gmyr V, Lobert D, Dechaumes A, Kerr-Conte J, Pattou F, Hober D.

Viruses. 2019 Jul 2;11(7). pii: E597. doi: 10.3390/v11070597.

7.

Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes.

Miguel-Escalada I, Bonàs-Guarch S, Cebola I, Ponsa-Cobas J, Mendieta-Esteban J, Atla G, Javierre BM, Rolando DMY, Farabella I, Morgan CC, García-Hurtado J, Beucher A, Morán I, Pasquali L, Ramos-Rodríguez M, Appel EVR, Linneberg A, Gjesing AP, Witte DR, Pedersen O, Grarup N, Ravassard P, Torrents D, Mercader JM, Piemonti L, Berney T, de Koning EJP, Kerr-Conte J, Pattou F, Fedko IO, Groop L, Prokopenko I, Hansen T, Marti-Renom MA, Fraser P, Ferrer J.

Nat Genet. 2019 Jul;51(7):1137-1148. doi: 10.1038/s41588-019-0457-0. Epub 2019 Jun 28.

8.

O-GlcNacylation Links TxNIP to Inflammasome Activation in Pancreatic β Cells.

Filhoulaud G, Benhamed F, Pagesy P, Bonner C, Fardini Y, Ilias A, Movassat J, Burnol AF, Guilmeau S, Kerr-Conte J, Pattou F, Issad T, Postic C.

Front Endocrinol (Lausanne). 2019 May 21;10:291. doi: 10.3389/fendo.2019.00291. eCollection 2019.

9.

Safety of Islet Autotransplantation After Pancreatectomy for Adenocarcinoma.

Renaud F, Chetboun M, Thevenet J, Delalleau N, Gmyr V, Hubert T, Bonner C, Messager M, Leteurtre E, Mariette C, Kerr-Conte J, Piessen G, Pattou F.

Transplantation. 2019 Jan;103(1):177-181. doi: 10.1097/TP.0000000000002419.

PMID:
30113997
10.

Neuronatin regulates pancreatic β cell insulin content and secretion.

Millership SJ, Da Silva Xavier G, Choudhury AI, Bertazzo S, Chabosseau P, Pedroni SM, Irvine EE, Montoya A, Faull P, Taylor WR, Kerr-Conte J, Pattou F, Ferrer J, Christian M, John RM, Latreille M, Liu M, Rutter GA, Scott J, Withers DJ.

J Clin Invest. 2018 Aug 1;128(8):3369-3381. doi: 10.1172/JCI120115. Epub 2018 Jul 9.

11.

Islet transplantation versus insulin therapy in patients with type 1 diabetes with severe hypoglycaemia or poorly controlled glycaemia after kidney transplantation (TRIMECO): a multicentre, randomised controlled trial.

Lablanche S, Vantyghem MC, Kessler L, Wojtusciszyn A, Borot S, Thivolet C, Girerd S, Bosco D, Bosson JL, Colin C, Tetaz R, Logerot S, Kerr-Conte J, Renard E, Penfornis A, Morelon E, Buron F, Skaare K, Grguric G, Camillo-Brault C, Egelhofer H, Benomar K, Badet L, Berney T, Pattou F, Benhamou PY; TRIMECO trial investigators.

Lancet Diabetes Endocrinol. 2018 Jul;6(7):527-537. doi: 10.1016/S2213-8587(18)30078-0. Epub 2018 May 15.

PMID:
29776895
12.

The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects β-cells against stress-induced apoptosis.

Baquié M, St-Onge L, Kerr-Conte J, Cobo-Vuilleumier N, Lorenzo PI, Jimenez Moreno CM, Cederroth CR, Nef S, Borot S, Bosco D, Wang H, Marchetti P, Pattou F, Wollheim CB, Gauthier BR.

Hum Mol Genet. 2018 Jan 15;27(2):406. doi: 10.1093/hmg/ddx402. No abstract available.

PMID:
29186426
13.

Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production.

Dalmas E, Lehmann FM, Dror E, Wueest S, Thienel C, Borsigova M, Stawiski M, Traunecker E, Lucchini FC, Dapito DH, Kallert SM, Guigas B, Pattou F, Kerr-Conte J, Maechler P, Girard JP, Konrad D, Wolfrum C, Böni-Schnetzler M, Finke D, Donath MY.

Immunity. 2017 Nov 21;47(5):928-942.e7. doi: 10.1016/j.immuni.2017.10.015.

14.

Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion.

Ndiaye FK, Ortalli A, Canouil M, Huyvaert M, Salazar-Cardozo C, Lecoeur C, Verbanck M, Pawlowski V, Boutry R, Durand E, Rabearivelo I, Sand O, Marselli L, Kerr-Conte J, Chandra V, Scharfmann R, Poulain-Godefroy O, Marchetti P, Pattou F, Abderrahmani A, Froguel P, Bonnefond A.

Mol Metab. 2017 Apr 8;6(6):459-470. doi: 10.1016/j.molmet.2017.03.011. eCollection 2017 Jun.

15.

Pharmacological approach to understanding the control of insulin secretion in human islets.

Henquin JC, Dufrane D, Gmyr V, Kerr-Conte J, Nenquin M.

Diabetes Obes Metab. 2017 Aug;19(8):1061-1070. doi: 10.1111/dom.12887. Epub 2017 Mar 31.

PMID:
28116849
16.

Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation.

Dror E, Dalmas E, Meier DT, Wueest S, Thévenet J, Thienel C, Timper K, Nordmann TM, Traub S, Schulze F, Item F, Vallois D, Pattou F, Kerr-Conte J, Lavallard V, Berney T, Thorens B, Konrad D, Böni-Schnetzler M, Donath MY.

Nat Immunol. 2017 Mar;18(3):283-292. doi: 10.1038/ni.3659. Epub 2017 Jan 16.

17.

Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks.

Akerman I, Tu Z, Beucher A, Rolando DMY, Sauty-Colace C, Benazra M, Nakic N, Yang J, Wang H, Pasquali L, Moran I, Garcia-Hurtado J, Castro N, Gonzalez-Franco R, Stewart AF, Bonner C, Piemonti L, Berney T, Groop L, Kerr-Conte J, Pattou F, Argmann C, Schadt E, Ravassard P, Ferrer J.

Cell Metab. 2017 Feb 7;25(2):400-411. doi: 10.1016/j.cmet.2016.11.016. Epub 2016 Dec 29.

18.

Human Recombinant Antithrombin (ATryn®) Administration Improves Survival and Prevents Intravascular Coagulation After Intraportal Islet Transplantation in a Piglet Model.

Gmyr V, Bonner C, Moerman E, Tournoys A, Delalleau N, Quenon A, Thevenet J, Chetboun M, Kerr-Conte J, Pattou F, Hubert T, Jourdain M.

Cell Transplant. 2017 Feb 16;26(2):309-317. doi: 10.3727/096368916X693554. Epub 2016 Oct 27.

19.

Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis.

Ben-Othman N, Vieira A, Courtney M, Record F, Gjernes E, Avolio F, Hadzic B, Druelle N, Napolitano T, Navarro-Sanz S, Silvano S, Al-Hasani K, Pfeifer A, Lacas-Gervais S, Leuckx G, Marroquí L, Thévenet J, Madsen OD, Eizirik DL, Heimberg H, Kerr-Conte J, Pattou F, Mansouri A, Collombat P.

Cell. 2017 Jan 12;168(1-2):73-85.e11. doi: 10.1016/j.cell.2016.11.002. Epub 2016 Dec 1.

20.

Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL.

Plaisance V, Brajkovic S, Tenenbaum M, Favre D, Ezanno H, Bonnefond A, Bonner C, Gmyr V, Kerr-Conte J, Gauthier BR, Widmann C, Waeber G, Pattou F, Froguel P, Abderrahmani A.

PLoS One. 2016 Sep 16;11(9):e0163046. doi: 10.1371/journal.pone.0163046. eCollection 2016.

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