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Items: 1 to 20 of 30

1.

Synergistic PA and HA mutations confer mouse adaptation of a contemporary A/H3N2 influenza virus.

Baz M, M'hamdi Z, Carbonneau J, Lavigne S, Couture C, Abed Y, Boivin G.

Sci Rep. 2019 Nov 12;9(1):16616. doi: 10.1038/s41598-019-51877-4.

2.

Strain-Dependent Impact of G and SH Deletions Provide New Insights for Live-Attenuated HMPV Vaccine Development.

Dubois J, Pizzorno A, Cavanagh MH, Padey B, Nicolas de Lamballerie C, Uyar O, Venable MC, Carbonneau J, Traversier A, Julien T, Lavigne S, Couture C, Lina B, Hamelin MÈ, Terrier O, Rosa-Calatrava M, Boivin G.

Vaccines (Basel). 2019 Oct 30;7(4). pii: E164. doi: 10.3390/vaccines7040164.

3.

Impact of the Baloxavir-Resistant Polymerase Acid I38T Substitution on the Fitness of Contemporary Influenza A(H1N1)pdm09 and A(H3N2) Strains.

Checkmahomed L, M'hamdi Z, Carbonneau J, Venable MC, Baz M, Abed Y, Boivin G.

J Infect Dis. 2020 Jan 1;221(1):63-70. doi: 10.1093/infdis/jiz418.

PMID:
31419295
4.

The Val430Ile neuraminidase (NA) substitution, identified in influenza B virus isolates, impacts the catalytic 116Arg residue causing reduced susceptibility to NA inhibitors.

Abed Y, Fage C, Checkmahomed L, Begin G, Carbonneau J, Lague P, Boivin G.

Antiviral Res. 2019 Oct;170:104561. doi: 10.1016/j.antiviral.2019.104561. Epub 2019 Jul 16.

PMID:
31323237
5.

Reduced Susceptibility to Neuraminidase Inhibitors in Influenza B Isolate, Canada.

Abed Y, Fage C, Lagüe P, Carbonneau J, Papenburg J, Vinh DC, Boivin G.

Emerg Infect Dis. 2019 Apr;25(4):838-840. doi: 10.3201/eid2504.181554.

6.

Design and Validation with Influenza A Virus of an Aerosol Transmission Chamber for Ferrets.

Turgeon N, Hamelin MÈ, Verreault D, Lévesque A, Rhéaume C, Carbonneau J, Checkmahomed L, Girard M, Boivin G, Duchaine C.

Int J Environ Res Public Health. 2019 Feb 19;16(4). pii: E609. doi: 10.3390/ijerph16040609.

7.

Molecular and epidemiologic investigation of a rhinovirus outbreak in a neonatal intensive care unit.

El Idrissi KR, Isabel S, Carbonneau J, Lafond M, Quach C, Caya C, Fontela PS, Beltempo M, Boivin G, Lefebvre MA, Papenburg J.

Infect Control Hosp Epidemiol. 2019 Feb;40(2):245-247. doi: 10.1017/ice.2018.311. Epub 2018 Dec 5.

PMID:
30516128
8.
9.

Comparison of early and recent influenza A(H1N1)pdm09 isolates harboring or not the H275Y neuraminidase mutation, in vitro and in animal models.

Abed Y, Tu V, Carbonneau J, Checkmahomed L, Venable MC, Fage C, Marie-Ève-Hamelin, Dufresne SF, Kobinger G, Boivin G.

Antiviral Res. 2018 Nov;159:26-34. doi: 10.1016/j.antiviral.2018.09.007. Epub 2018 Sep 13.

PMID:
30219318
10.

Zika-Induced Male Infertility in Mice Is Potentially Reversible and Preventable by Deoxyribonucleic Acid Immunization.

de La Vega MA, Piret J, Griffin BD, Rhéaume C, Venable MC, Carbonneau J, Couture C, das Neves Almeida R, Tremblay RR, Magalhães KG, Park YK, Roberts CC, Maslow JN, Sardesai NY, Kim JJ, Muthumani K, Weiner DB, Kobinger GP, Boivin G.

J Infect Dis. 2019 Jan 9;219(3):365-374. doi: 10.1093/infdis/jiy336.

11.

Predominant role of IPS-1 over TRIF adaptor proteins in early innate immune response against Zika virus in mice.

Piret J, Carbonneau J, Rhéaume C, Baz M, Boivin G.

J Gen Virol. 2018 Feb;99(2):209-218. doi: 10.1099/jgv.0.000992. Epub 2018 Jan 3.

PMID:
29297844
12.

Peramivir susceptibilities of recombinant influenza A and B variants selected with various neuraminidase inhibitors.

Fage C, Tu V, Carbonneau J, Abed Y, Boivin G.

Antivir Ther. 2017;22(8):711-716. doi: 10.3851/IMP3158.

PMID:
29082897
13.

Cell Culture Systems To Study Human Herpesvirus 6A/B Chromosomal Integration.

Gravel A, Dubuc I, Wallaschek N, Gilbert-Girard S, Collin V, Hall-Sedlak R, Jerome KR, Mori Y, Carbonneau J, Boivin G, Kaufer BB, Flamand L.

J Virol. 2017 Jun 26;91(14). pii: e00437-17. doi: 10.1128/JVI.00437-17. Print 2017 Jul 15.

14.

The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness.

Tu V, Abed Y, Barbeau X, Carbonneau J, Fage C, Lagüe P, Boivin G.

Antiviral Res. 2017 Jan;137:6-13. doi: 10.1016/j.antiviral.2016.11.007. Epub 2016 Nov 9.

PMID:
27838351
15.

Droplet digital PCR to investigate quasi-species at codons 119 and 275 of the A(H1N1)pdm09 neuraminidase during zanamivir and oseltamivir therapies.

Abed Y, Carbonneau J, L'Huillier AG, Kaiser L, Boivin G.

J Med Virol. 2017 Apr;89(4):737-741. doi: 10.1002/jmv.24680. Epub 2016 Sep 14.

PMID:
27602879
16.

Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets.

Ann J, Abed Y, Beaulieu E, Bouhy X, Joly MH, Dubé K, Carbonneau J, Hamelin ME, Mallett C, Boivin G.

Influenza Other Respir Viruses. 2016 Mar;10(2):122-6. doi: 10.1111/irv.12356. Epub 2016 Jan 29.

17.

Optimization of Droplet Digital PCR from RNA and DNA extracts with direct comparison to RT-qPCR: Clinical implications for quantification of Oseltamivir-resistant subpopulations.

Taylor SC, Carbonneau J, Shelton DN, Boivin G.

J Virol Methods. 2015 Nov;224:58-66. doi: 10.1016/j.jviromet.2015.08.014. Epub 2015 Aug 24.

18.

Effect of in vitro syncytium formation on the severity of human metapneumovirus disease in a murine model.

Aerts L, Cavanagh MH, Dubois J, Carbonneau J, Rhéaume C, Lavigne S, Couture C, Hamelin MÈ, Boivin G.

PLoS One. 2015 Mar 24;10(3):e0120283. doi: 10.1371/journal.pone.0120283. eCollection 2015.

19.

Adjuvant effect of the human metapneumovirus (HMPV) matrix protein in HMPV subunit vaccines.

Aerts L, Rhéaume C, Carbonneau J, Lavigne S, Couture C, Hamelin MÈ, Boivin G.

J Gen Virol. 2015 Apr;96(Pt 4):767-74. doi: 10.1099/vir.0.000031. Epub 2014 Dec 17.

PMID:
25519171
20.

Evolution of oseltamivir resistance mutations in Influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice.

Pizzorno A, Abed Y, Plante PL, Carbonneau J, Baz M, Hamelin MÈ, Corbeil J, Boivin G.

Antimicrob Agents Chemother. 2014 Nov;58(11):6398-405. doi: 10.1128/AAC.02956-14. Epub 2014 Aug 11.

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