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Items: 1 to 20 of 40

1.

Cyp2c44 regulates prostaglandin synthesis, lymphangiogenesis, and metastasis in a mouse model of breast cancer.

Kesavan R, Frömel T, Zukunft S, Laban H, Geyer A, Naeem Z, Heidler J, Wittig I, Elwakeel E, Brüne B, Weigert A, Popp R, Fleming I.

Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):5923-5930. doi: 10.1073/pnas.1921381117. Epub 2020 Mar 2.

PMID:
32123095
2.

Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia.

Szibor M, Schreckenberg R, Gizatullina Z, Dufour E, Wiesnet M, Dhandapani PK, Debska-Vielhaber G, Heidler J, Wittig I, Nyman TA, Gärtner U, Hall AR, Pell V, Viscomi C, Krieg T, Murphy MP, Braun T, Gellerich FN, Schlüter KD, Jacobs HT.

J Cell Mol Med. 2020 Feb 10. doi: 10.1111/jcmm.15043. [Epub ahead of print]

3.

Pathogenic Bi-allelic Mutations in NDUFAF8 Cause Leigh Syndrome with an Isolated Complex I Deficiency.

Alston CL, Veling MT, Heidler J, Taylor LS, Alaimo JT, Sung AY, He L, Hopton S, Broomfield A, Pavaine J, Diaz J, Leon E, Wolf P, McFarland R, Prokisch H, Wortmann SB, Bonnen PE, Wittig I, Pagliarini DJ, Taylor RW.

Am J Hum Genet. 2020 Jan 2;106(1):92-101. doi: 10.1016/j.ajhg.2019.12.001. Epub 2019 Dec 19.

4.

Bioenergetic consequences from xenotopic expression of a tunicate AOX in mouse mitochondria: Switch from RET and ROS to FET.

Szibor M, Gainutdinov T, Fernandez-Vizarra E, Dufour E, Gizatullina Z, Debska-Vielhaber G, Heidler J, Wittig I, Viscomi C, Gellerich F, Moore AL.

Biochim Biophys Acta Bioenerg. 2020 Feb 1;1861(2):148137. doi: 10.1016/j.bbabio.2019.148137. Epub 2019 Dec 9.

5.

Global Proteome of LonP1+/- Mouse Embryonal Fibroblasts Reveals Impact on Respiratory Chain, but No Interdependence between Eral1 and Mitoribosomes.

Key J, Kohli A, Bárcena C, López-Otín C, Heidler J, Wittig I, Auburger G.

Int J Mol Sci. 2019 Sep 12;20(18). pii: E4523. doi: 10.3390/ijms20184523.

6.

Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition.

Siragusa M, Thöle J, Bibli SI, Luck B, Loot AE, de Silva K, Wittig I, Heidler J, Stingl H, Randriamboavonjy V, Kohlstedt K, Brüne B, Weigert A, Fisslthaler B, Fleming I.

EMBO J. 2019 Sep 2;38(17):e100938. doi: 10.15252/embj.2018100938. Epub 2019 Jul 22.

PMID:
31328803
7.

Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis.

Fisslthaler B, Zippel N, Abdel Malik R, Delgado Lagos F, Zukunft S, Thoele J, Siuda D, Soehnlein O, Wittig I, Heidler J, Weigert A, Fleming I.

Int J Mol Sci. 2019 Jun 19;20(12). pii: E3005. doi: 10.3390/ijms20123005.

8.

TLR2-Dependent Reversible Oxidation of Connexin 43 at Cys260 Modifies Electrical Coupling After Experimental Myocardial Ischemia/Reperfusion.

Raimann FJ, Dröse S, Bonke E, Schneider L, Tybl E, Wittig I, Heidler J, Heide H, Josipovic I, Leisegang M, Brandes RP, Roeper J, Zacharowski K, Mersmann J.

J Cardiovasc Transl Res. 2019 Oct;12(5):478-487. doi: 10.1007/s12265-019-09887-0. Epub 2019 Apr 8.

PMID:
30963423
9.

BIAM switch assay coupled to mass spectrometry identifies novel redox targets of NADPH oxidase 4.

Löwe O, Rezende F, Heidler J, Wittig I, Helfinger V, Brandes RP, Schröder K.

Redox Biol. 2019 Feb;21:101125. doi: 10.1016/j.redox.2019.101125. Epub 2019 Jan 29.

10.

Deep proteome of human nNOS/NOS1-positive versus MOCK SH-SY5Y neuroblastoma cells under full nutrition, serum free starvation and rapamycin treatment.

Heidler J, Valek L, Wittig I, Tegeder I.

Data Brief. 2018 Oct 26;21:1309-1314. doi: 10.1016/j.dib.2018.10.079. eCollection 2018 Dec.

11.

Redox-proteomes of human NOS1-transduced versus MOCK SH-SY5Y neuroblastoma cells under full nutrition, serum-free starvation, and rapamycin treatment.

Heidler J, Valek L, Wittig I, Tegeder I.

Data Brief. 2018 Oct 26;21:1302-1308. doi: 10.1016/j.dib.2018.10.078. eCollection 2018 Dec.

12.

Nitric oxide contributes to protein homeostasis by S-nitrosylations of the chaperone HSPA8 and the ubiquitin ligase UBE2D.

Valek L, Heidler J, Scheving R, Wittig I, Tegeder I.

Redox Biol. 2019 Jan;20:217-235. doi: 10.1016/j.redox.2018.10.002. Epub 2018 Oct 16.

13.

Bi-allelic Mutations in NDUFA6 Establish Its Role in Early-Onset Isolated Mitochondrial Complex I Deficiency.

Alston CL, Heidler J, Dibley MG, Kremer LS, Taylor LS, Fratter C, French CE, Glasgow RIC, Feichtinger RG, Delon I, Pagnamenta AT, Dolling H, Lemonde H, Aiton N, Bjørnstad A, Henneke L, Gärtner J, Thiele H, Tauchmannova K, Quaghebeur G, Houstek J, Sperl W, Raymond FL, Prokisch H, Mayr JA, McFarland R, Poulton J, Ryan MT, Wittig I, Henneke M, Taylor RW.

Am J Hum Genet. 2018 Oct 4;103(4):592-601. doi: 10.1016/j.ajhg.2018.08.013. Epub 2018 Sep 20.

14.

Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis.

Bibli SI, Hu J, Sigala F, Wittig I, Heidler J, Zukunft S, Tsilimigras DI, Randriamboavonjy V, Wittig J, Kojonazarov B, Schürmann C, Siragusa M, Siuda D, Luck B, Abdel Malik R, Filis KA, Zografos G, Chen C, Wang DW, Pfeilschifter J, Brandes RP, Szabo C, Papapetropoulos A, Fleming I.

Circulation. 2019 Jan 2;139(1):101-114. doi: 10.1161/CIRCULATIONAHA.118.034757.

PMID:
29970364
15.

Metabolic Maturation during Muscle Stem Cell Differentiation Is Achieved by miR-1/133a-Mediated Inhibition of the Dlk1-Dio3 Mega Gene Cluster.

Wüst S, Dröse S, Heidler J, Wittig I, Klockner I, Franko A, Bonke E, Günther S, Gärtner U, Boettger T, Braun T.

Cell Metab. 2018 May 1;27(5):1026-1039.e6. doi: 10.1016/j.cmet.2018.02.022. Epub 2018 Apr 5.

16.

Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors.

Lampe S, Kunze M, Scholz A, Brauß TF, Winslow S, Simm S, Keller M, Heidler J, Wittig I, Brüne B, Schmid T.

Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):147-157. doi: 10.1016/j.bbagrm.2018.01.010. Epub 2018 Jan 31. No abstract available.

PMID:
29378331
17.

Acyl modification and binding of mitochondrial ACP to multiprotein complexes.

Angerer H, Schönborn S, Gorka J, Bahr U, Karas M, Wittig I, Heidler J, Hoffmann J, Morgner N, Zickermann V.

Biochim Biophys Acta Mol Cell Res. 2017 Oct;1864(10):1913-1920. doi: 10.1016/j.bbamcr.2017.08.006. Epub 2017 Aug 9.

18.

Coi1 is a novel assembly factor of the yeast complex III-complex IV supercomplex.

Singhal RK, Kruse C, Heidler J, Strecker V, Zwicker K, Düsterwald L, Westermann B, Herrmann JM, Wittig I, Rapaport D.

Mol Biol Cell. 2017 Aug 9. pii: mbc.E17-02-0093. doi: 10.1091/mbc.E17-02-0093. [Epub ahead of print]

19.

Loss of synaptic zinc transport in progranulin deficient mice may contribute to progranulin-associated psychopathology and chronic pain.

Hardt S, Heidler J, Albuquerque B, Valek L, Altmann C, Wilken-Schmitz A, Schäfer MKE, Wittig I, Tegeder I.

Biochim Biophys Acta Mol Basis Dis. 2017 Nov;1863(11):2727-2745. doi: 10.1016/j.bbadis.2017.07.014. Epub 2017 Jul 15.

20.

Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase: A Possible Key to Future Antileukotriene Therapy.

Roos J, Peters M, Maucher IV, Kühn B, Fettel J, Hellmuth N, Brat C, Sommer B, Urbschat A, Piesche M, Vogel A, Proschak E, Blöcher R, Buscató E, Häfner AK, Matrone C, Werz O, Heidler J, Wittig I, Angioni C, Geisslinger G, Parnham MJ, Zacharowski K, Steinhilber D, Maier TJ.

Antioxid Redox Signal. 2018 May 10;28(14):1265-1285. doi: 10.1089/ars.2017.7155. Epub 2017 Sep 8.

PMID:
28699354

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