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Items: 1 to 20 of 62


Deep mutational scanning of the Neisseria meningitidis major pilin reveals the importance of pilus tip-mediated adhesion.

Kennouche P, Charles-Orszag A, Nishiguchi D, Goussard S, Imhaus AF, Dupré M, Chamot-Rooke J, Duménil G.

EMBO J. 2019 Nov 15;38(22):e102145. doi: 10.15252/embj.2019102145. Epub 2019 Oct 14.


A five-level classification system for proteoform identifications.

Smith LM, Thomas PM, Shortreed MR, Schaffer LV, Fellers RT, LeDuc RD, Tucholski T, Ge Y, Agar JN, Anderson LC, Chamot-Rooke J, Gault J, Loo JA, Paša-Tolić L, Robinson CV, Schlüter H, Tsybin YO, Vilaseca M, Vizcaíno JA, Danis PO, Kelleher NL.

Nat Methods. 2019 Oct;16(10):939-940. doi: 10.1038/s41592-019-0573-x. No abstract available.


Best practices and benchmarks for intact protein analysis for top-down mass spectrometry.

Donnelly DP, Rawlins CM, DeHart CJ, Fornelli L, Schachner LF, Lin Z, Lippens JL, Aluri KC, Sarin R, Chen B, Lantz C, Jung W, Johnson KR, Koller A, Wolff JJ, Campuzano IDG, Auclair JR, Ivanov AR, Whitelegge JP, Paša-Tolić L, Chamot-Rooke J, Danis PO, Smith LM, Tsybin YO, Loo JA, Ge Y, Kelleher NL, Agar JN.

Nat Methods. 2019 Jul;16(7):587-594. doi: 10.1038/s41592-019-0457-0. Epub 2019 Jun 27. Review.


Top-Down Garbage Collector: a tool for selecting high-quality top-down proteomics mass spectra.

Lima DB, Silva ARF, Dupré M, Santos MDM, Clasen MA, Kurt LU, Aquino PF, Barbosa VC, Carvalho PC, Chamot-Rooke J.

Bioinformatics. 2019 Sep 15;35(18):3489-3490. doi: 10.1093/bioinformatics/btz085.


Consensus designs and thermal stability determinants of a human glutamate transporter.

Cirri E, Brier S, Assal R, Canul-Tec JC, Chamot-Rooke J, Reyes N.

Elife. 2018 Oct 18;7. pii: e40110. doi: 10.7554/eLife.40110.


Biogenesis and structure of a type VI secretion baseplate.

Cherrak Y, Rapisarda C, Pellarin R, Bouvier G, Bardiaux B, Allain F, Malosse C, Rey M, Chamot-Rooke J, Cascales E, Fronzes R, Durand E.

Nat Microbiol. 2018 Dec;3(12):1404-1416. doi: 10.1038/s41564-018-0260-1. Epub 2018 Oct 15.


eXL-MS: An Enhanced Cross-Linking Mass Spectrometry Workflow To Study Protein Complexes.

Rey M, Dupré M, Lopez-Neira I, Duchateau M, Chamot-Rooke J.

Anal Chem. 2018 Sep 18;90(18):10707-10714. doi: 10.1021/acs.analchem.8b00737. Epub 2018 Aug 31.


Characterization of LE3 and LE4, the only lytic phages known to infect the spirochete Leptospira.

Schiettekatte O, Vincent AT, Malosse C, Lechat P, Chamot-Rooke J, Veyrier FJ, Picardeau M, Bourhy P.

Sci Rep. 2018 Aug 6;8(1):11781. doi: 10.1038/s41598-018-29983-6.


A step-by-step in crystallo guide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase.

Williams AH, Wheeler R, Rateau L, Malosse C, Chamot-Rooke J, Haouz A, Taha MK, Boneca IG.

J Biol Chem. 2018 Apr 20;293(16):6000-6010. doi: 10.1074/jbc.RA117.001095. Epub 2018 Feb 26.


ProForma: A Standard Proteoform Notation.

LeDuc RD, Schwämmle V, Shortreed MR, Cesnik AJ, Solntsev SK, Shaw JB, Martin MJ, Vizcaino JA, Alpi E, Danis P, Kelleher NL, Smith LM, Ge Y, Agar JN, Chamot-Rooke J, Loo JA, Pasa-Tolic L, Tsybin YO.

J Proteome Res. 2018 Mar 2;17(3):1321-1325. doi: 10.1021/acs.jproteome.7b00851. Epub 2018 Feb 14.


Glycosylphosphatidylinositol Anchors from Galactomannan and GPI-Anchored Protein Are Synthesized by Distinct Pathways in Aspergillus fumigatus.

Li J, Mouyna I, Henry C, Moyrand F, Malosse C, Chamot-Rooke J, Janbon G, Latgé JP, Fontaine T.

J Fungi (Basel). 2018 Feb 2;4(1). pii: E19. doi: 10.3390/jof4010019.


Characterization of homodimer interfaces with cross-linking mass spectrometry and isotopically labeled proteins.

Lima DB, Melchior JT, Morris J, Barbosa VC, Chamot-Rooke J, Fioramonte M, Souza TACB, Fischer JSG, Gozzo FC, Carvalho PC, Davidson WS.

Nat Protoc. 2018 Mar;13(3):431-458. doi: 10.1038/nprot.2017.113. Epub 2018 Feb 1.


Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough.

O'Brien DP, Perez ACS, Karst J, Cannella SE, Enguéné VYN, Hessel A, Raoux-Barbot D, Voegele A, Subrini O, Davi M, Guijarro JI, Raynal B, Baron B, England P, Hernandez B, Ghomi M, Hourdel V, Malosse C, Chamot-Rooke J, Vachette P, Durand D, Brier S, Ladant D, Chenal A.

Toxicon. 2018 Jul;149:37-44. doi: 10.1016/j.toxicon.2018.01.007. Epub 2018 Jan 12. Review.


Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis.

O'Brien DP, Durand D, Voegele A, Hourdel V, Davi M, Chamot-Rooke J, Vachette P, Brier S, Ladant D, Chenal A.

PLoS Biol. 2017 Dec 29;15(12):e2004486. doi: 10.1371/journal.pbio.2004486. eCollection 2017 Dec.


The stress sigma factor of RNA polymerase RpoS/σS is a solvent-exposed open molecule in solution.

Cavaliere P, Brier S, Filipenko P, Sizun C, Raynal B, Bonneté F, Levi-Acobas F, Bellalou J, England P, Chamot-Rooke J, Mayer C, Norel F.

Biochem J. 2018 Jan 15;475(1):341-354. doi: 10.1042/BCJ20170768.


Regulation of NF-κB by the p105-ABIN2-TPL2 complex and RelAp43 during rabies virus infection.

Besson B, Sonthonnax F, Duchateau M, Ben Khalifa Y, Larrous F, Eun H, Hourdel V, Matondo M, Chamot-Rooke J, Grailhe R, Bourhy H.

PLoS Pathog. 2017 Oct 30;13(10):e1006697. doi: 10.1371/journal.ppat.1006697. eCollection 2017 Oct.


Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem.

Delhommel F, Cordier F, Bardiaux B, Bouvier G, Colcombet-Cazenave B, Brier S, Raynal B, Nouaille S, Bahloul A, Chamot-Rooke J, Nilges M, Petit C, Wolff N.

Structure. 2017 Nov 7;25(11):1645-1656.e5. doi: 10.1016/j.str.2017.08.013. Epub 2017 Sep 28.


Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates.

Bouchez V, Douché T, Dazas M, Delaplane S, Matondo M, Chamot-Rooke J, Guiso N.

Toxins (Basel). 2017 Sep 26;9(10). pii: E304. doi: 10.3390/toxins9100304.


Structure and allosteric inhibition of excitatory amino acid transporter 1.

Canul-Tec JC, Assal R, Cirri E, Legrand P, Brier S, Chamot-Rooke J, Reyes N.

Nature. 2017 Apr 27;544(7651):446-451. doi: 10.1038/nature22064. Epub 2017 Apr 19.


DiagnoProt: a tool for discovery of new molecules by mass spectrometry.

Silva ARF, Lima DB, Leyva A, Duran R, Batthyany C, Aquino PF, Leal JC, Rodriguez JE, Domont GB, Santos MDM, Chamot-Rooke J, Barbosa VC, Carvalho PC.

Bioinformatics. 2017 Jun 15;33(12):1883-1885. doi: 10.1093/bioinformatics/btx093.


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