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Items: 1 to 20 of 120

1.

Connexin 43 deletion in astrocytes promotes CNS remyelination by modulating local inflammation.

Li T, Niu J, Yu G, Ezan P, Yi C, Wang X, Koulakoff A, Gao X, Chen X, Sáez JC, Giaume C, Xiao L.

Glia. 2019 Dec 23. doi: 10.1002/glia.23770. [Epub ahead of print]

PMID:
31868275
2.

Pannexin-1 Channels Are Essential for Mast Cell Degranulation Triggered During Type I Hypersensitivity Reactions.

Harcha PA, López X, Sáez PJ, Fernández P, Barría I, Martínez AD, Sáez JC.

Front Immunol. 2019 Nov 29;10:2703. doi: 10.3389/fimmu.2019.02703. eCollection 2019.

3.

Direct Intercellular Communications and Cancer: A Snapshot of the Biological Roles of Connexins in Prostate Cancer.

Asencio-Barría C, Defamie N, Sáez JC, Mesnil M, Godoy AS.

Cancers (Basel). 2019 Sep 14;11(9). pii: E1370. doi: 10.3390/cancers11091370. Review.

4.

Role of a RhoA/ROCK-Dependent Pathway on Renal Connexin43 Regulation in the Angiotensin II-Induced Renal Damage.

Gómez GI, Velarde V, Sáez JC.

Int J Mol Sci. 2019 Sep 7;20(18). pii: E4408. doi: 10.3390/ijms20184408.

5.

Gap junctions coordinate the propagation of glycogenolysis induced by norepinephrine in the pineal gland.

Eugenin EA, Valdebenito S, Gorska AM, Martínez AD, Bitran M, Sáez JC.

J Neurochem. 2019 Dec;151(5):558-569. doi: 10.1111/jnc.14846. Epub 2019 Oct 20.

PMID:
31381153
6.

De novo expression of functional connexins 43 and 45 hemichannels increases sarcolemmal permeability of skeletal myofibers during endotoxemia.

Cea LA, Balboa E, Vargas AA, Puebla C, Brañes MC, Escamilla R, Regueira T, Sáez JC.

Biochim Biophys Acta Mol Basis Dis. 2019 Oct 1;1865(10):2765-2773. doi: 10.1016/j.bbadis.2019.06.014. Epub 2019 Jun 20.

PMID:
31228617
7.

Astroglial Ca2+-Dependent Hyperexcitability Requires P2Y1 Purinergic Receptors and Pannexin-1 Channel Activation in a Chronic Model of Epilepsy.

Wellmann M, Álvarez-Ferradas C, Maturana CJ, Sáez JC, Bonansco C.

Front Cell Neurosci. 2018 Nov 23;12:446. doi: 10.3389/fncel.2018.00446. eCollection 2018.

8.

Innexins: Expression, Regulation, and Functions.

Güiza J, Barría I, Sáez JC, Vega JL.

Front Physiol. 2018 Oct 11;9:1414. doi: 10.3389/fphys.2018.01414. eCollection 2018. Review.

9.

Connexin 43 Hemichannel Activity Promoted by Pro-Inflammatory Cytokines and High Glucose Alters Endothelial Cell Function.

Sáez JC, Contreras-Duarte S, Gómez GI, Labra VC, Santibañez CA, Gajardo-Gómez R, Avendaño BC, Díaz EF, Montero TD, Velarde V, Orellana JA.

Front Immunol. 2018 Aug 15;9:1899. doi: 10.3389/fimmu.2018.01899. eCollection 2018.

10.

Involvement of Connexin Hemichannels in the Inflammatory Response of Chronic Diseases.

Sáez JC, Green C.

Int J Mol Sci. 2018 Aug 21;19(9). pii: E2469. doi: 10.3390/ijms19092469.

11.

Role of calcium permeable channels in dendritic cell migration.

Sáez PJ, Sáez JC, Lennon-Duménil AM, Vargas P.

Curr Opin Immunol. 2018 Jun;52:74-80. doi: 10.1016/j.coi.2018.04.005. Epub 2018 Apr 30. Review.

PMID:
29715579
12.

Angiotensin II-Induced Mesangial Cell Damaged Is Preceded by Cell Membrane Permeabilization Due to Upregulation of Non-Selective Channels.

Gómez GI, Fernández P, Velarde V, Sáez JC.

Int J Mol Sci. 2018 Mar 23;19(4). pii: E957. doi: 10.3390/ijms19040957.

13.

ATP promotes the fast migration of dendritic cells through the activity of pannexin 1 channels and P2X7 receptors.

Sáez PJ, Vargas P, Shoji KF, Harcha PA, Lennon-Duménil AM, Sáez JC.

Sci Signal. 2017 Nov 21;10(506). pii: eaah7107. doi: 10.1126/scisignal.aah7107.

PMID:
29162744
14.

Trypanosoma cruzi Infection Induces Pannexin-1 Channel Opening in Cardiac Myocytes.

Barría I, Güiza J, Cifuentes F, Zamorano P, Sáez JC, González J, Vega JL.

Am J Trop Med Hyg. 2018 Jan;98(1):105-112. doi: 10.4269/ajtmh.17-0293.

15.

Connexins and pannexins in Alzheimer's disease.

Giaume C, Sáez JC, Song W, Leybaert L, Naus CC.

Neurosci Lett. 2019 Mar 16;695:100-105. doi: 10.1016/j.neulet.2017.09.006. Epub 2017 Sep 8. Review.

PMID:
28893592
16.

Role of astrocyte connexin hemichannels in cortical spreading depression.

Rovegno M, Sáez JC.

Biochim Biophys Acta Biomembr. 2018 Jan;1860(1):216-223. doi: 10.1016/j.bbamem.2017.08.014. Epub 2017 Aug 31. Review.

17.

Inhibition of glial hemichannels by boldine treatment reduces neuronal suffering in a murine model of Alzheimer's disease.

Yi C, Ezan P, Fernández P, Schmitt J, Sáez JC, Giaume C, Koulakoff A.

Glia. 2017 Oct;65(10):1607-1625. doi: 10.1002/glia.23182. Epub 2017 Jul 13.

PMID:
28703353
18.

Connexin-Dependent Neuroglial Networking as a New Therapeutic Target.

Charvériat M, Naus CC, Leybaert L, Sáez JC, Giaume C.

Front Cell Neurosci. 2017 Jun 26;11:174. doi: 10.3389/fncel.2017.00174. eCollection 2017. Review.

19.

Connexins and Pannexins in Bone and Skeletal Muscle.

Plotkin LI, Davis HM, Cisterna BA, Sáez JC.

Curr Osteoporos Rep. 2017 Aug;15(4):326-334. doi: 10.1007/s11914-017-0374-z. Review.

20.

Sepsis-Induced Channelopathy in Skeletal Muscles is Associated with Expression of Non-Selective Channels.

Balboa E, Saavedra-Leiva F, Cea LA, Vargas AA, Ramírez V, Escamilla R, Sáez JC, Regueira T.

Shock. 2018 Feb;49(2):221-228. doi: 10.1097/SHK.0000000000000916.

PMID:
28562477

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