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Items: 1 to 20 of 40

1.

Models used to screen for the treatment of multidrug resistant cancer facilitated by transporter-based efflux.

Willers C, Svitina H, Rossouw MJ, Swanepoel RA, Hamman JH, Gouws C.

J Cancer Res Clin Oncol. 2019 Aug;145(8):1949-1976. doi: 10.1007/s00432-019-02973-5. Epub 2019 Jul 10. Review.

PMID:
31292714
2.

A sub-chronic Xysmalobium undulatum hepatotoxicity investigation in HepG2/C3A spheroid cultures compared to an in vivo model.

Calitz C, Hamman JH, Fey SJ, Viljoen AM, Gouws C, Wrzesinski K.

J Ethnopharmacol. 2019 Jul 15;239:111897. doi: 10.1016/j.jep.2019.111897. Epub 2019 Apr 19.

PMID:
31009705
3.

Drug Bioavailability Enhancing Agents of Natural Origin (Bioenhancers) that Modulate Drug Membrane Permeation and Pre-Systemic Metabolism.

Peterson B, Weyers M, Steenekamp JH, Steyn JD, Gouws C, Hamman JH.

Pharmaceutics. 2019 Jan 16;11(1). pii: E33. doi: 10.3390/pharmaceutics11010033. Review.

4.

Beneficial Pharmacokinetic Drug Interactions: A Tool to Improve the Bioavailability of Poorly Permeable Drugs.

Gerber W, Steyn JD, Kotzé AF, Hamman JH.

Pharmaceutics. 2018 Jul 26;10(3). pii: E106. doi: 10.3390/pharmaceutics10030106. Review.

5.

Toxicity and anti-prolific properties of Xysmalobium undulatum water extract during short-term exposure to two-dimensional and three-dimensional spheroid cell cultures.

Calitz C, Hamman JH, Viljoen AM, Fey SJ, Wrzesinski K, Gouws C.

Toxicol Mech Methods. 2018 Nov;28(9):641-652. doi: 10.1080/15376516.2018.1485805. Epub 2018 Sep 26.

PMID:
29873580
6.

Excipient-drug pharmacokinetic interactions: Effect of disintegrants on efflux across excised pig intestinal tissues.

Gerber W, Hamman JH, Steyn JD.

J Food Drug Anal. 2018 Apr;26(2S):S115-S124. doi: 10.1016/j.jfda.2018.01.007. Epub 2018 Feb 13.

7.

Recent advances in three-dimensional cell culturing to assess liver function and dysfunction: from a drug biotransformation and toxicity perspective.

Calitz C, Hamman JH, Fey SJ, Wrzesinski K, Gouws C.

Toxicol Mech Methods. 2018 Jun;28(5):369-385. doi: 10.1080/15376516.2017.1422580. Epub 2018 Jan 18. Review.

PMID:
29297242
8.

Recent developments in our understanding of the implications of traditional African medicine on drug metabolism.

Gouws C, Hamman JH.

Expert Opin Drug Metab Toxicol. 2018 Feb;14(2):161-168. doi: 10.1080/17425255.2018.1421171. Epub 2017 Dec 26. Review.

PMID:
29268027
9.

Topical Delivery of Withania somnifera Crude Extracts in Niosomes and Solid Lipid Nanoparticles.

Chinembiri TN, Gerber M, du Plessis LH, du Preez JL, Hamman JH, du Plessis J.

Pharmacogn Mag. 2017 Oct;13(Suppl 3):S663-S671. doi: 10.4103/pm.pm_489_16. Epub 2017 Oct 11.

10.

In vitro wound healing and cytotoxic activity of the gel and whole-leaf materials from selected aloe species.

Fox LT, Mazumder A, Dwivedi A, Gerber M, du Plessis J, Hamman JH.

J Ethnopharmacol. 2017 Mar 22;200:1-7. doi: 10.1016/j.jep.2017.02.017. Epub 2017 Feb 14.

PMID:
28229920
11.

Isolation and in vitro permeation of phenylpropylamino alkaloids from Khat (Catha edulis) across oral and intestinal mucosal tissues.

Atlabachew M, Combrinck S, Viljoen AM, Hamman JH, Gouws C.

J Ethnopharmacol. 2016 Dec 24;194:307-315. doi: 10.1016/j.jep.2016.09.012. Epub 2016 Sep 9.

PMID:
27616032
12.

Combining Chemical Permeation Enhancers for Synergistic Effects.

du Toit T, Malan MM, Lemmer HJ, Gouws C, Aucamp ME, Breytenbach WJ, Hamman JH.

Eur J Drug Metab Pharmacokinet. 2016 Oct;41(5):575-86. doi: 10.1007/s13318-015-0280-7.

PMID:
25939330
13.

Editorial: oral delivery of biotechnology based drugs: dream or reality?

Hamman JH.

Curr Pharm Biotechnol. 2014;15(7):639. No abstract available.

PMID:
25268827
14.

Skin permeation enhancement effects of the gel and whole-leaf materials of Aloe vera, Aloe marlothii and Aloe ferox.

Fox LT, Gerber M, du Preez JL, du Plessis J, Hamman JH.

J Pharm Pharmacol. 2015 Jan;67(1):96-106. doi: 10.1111/jphp.12311. Epub 2014 Sep 5.

PMID:
25196486
15.

Review of natural compounds for potential skin cancer treatment.

Chinembiri TN, du Plessis LH, Gerber M, Hamman JH, du Plessis J.

Molecules. 2014 Aug 6;19(8):11679-721. doi: 10.3390/molecules190811679. Review.

16.

In Vivo skin hydration and anti-erythema effects of Aloe vera, Aloe ferox and Aloe marlothii gel materials after single and multiple applications.

Fox LT, du Plessis J, Gerber M, van Zyl S, Boneschans B, Hamman JH.

Pharmacogn Mag. 2014 Apr;10(Suppl 2):S392-403. doi: 10.4103/0973-1296.133291.

17.

Impact of traditional African medicine on drug metabolism and transport.

Calitz C, Steenekamp JH, Steyn JD, Gouws C, Viljoen JM, Hamman JH.

Expert Opin Drug Metab Toxicol. 2014 Jul;10(7):991-1003. doi: 10.1517/17425255.2014.920321. Epub 2014 May 15. Review.

PMID:
24831257
18.

In vitro evaluation of the cytotoxic and apoptogenic properties of aloe whole leaf and gel materials.

du Plessis LH, Hamman JH.

Drug Chem Toxicol. 2014 Apr;37(2):169-77. doi: 10.3109/01480545.2013.834356. Epub 2013 Oct 11.

PMID:
24111784
19.

Direct compression of chitosan: process and formulation factors to improve powder flow and tablet performance.

Buys GM, du Plessis LH, Marais AF, Kotze AF, Hamman JH.

Curr Drug Deliv. 2013 Jun;10(3):348-56.

PMID:
23545146
20.

Paracellular drug absorption enhancement through tight junction modulation.

Lemmer HJ, Hamman JH.

Expert Opin Drug Deliv. 2013 Jan;10(1):103-14. doi: 10.1517/17425247.2013.745509. Epub 2012 Nov 20. Review.

PMID:
23163247

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