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Items: 1 to 20 of 36

1.

Beneficial Pharmacokinetic Drug Interactions: A Tool to Improve the Bioavailability of Poorly Permeable Drugs.

Gerber W, Steyn JD, Kotzé AF, Hamman JH.

Pharmaceutics. 2018 Jul 26;10(3). pii: E106. doi: 10.3390/pharmaceutics10030106. Review.

2.

Excipient-drug pharmacokinetic interactions: Effect of disintegrants on efflux across excised pig intestinal tissues.

Gerber W, Hamman JH, Steyn JD.

J Food Drug Anal. 2018 Apr;26(2S):S115-S124. doi: 10.1016/j.jfda.2018.01.007. Epub 2018 Feb 13.

3.

Recent advances in three-dimensional cell culturing to assess liver function and dysfunction: from a drug biotransformation and toxicity perspective.

Calitz C, Hamman JH, Fey SJ, Wrzesinski K, Gouws C.

Toxicol Mech Methods. 2018 Jun;28(5):369-385. doi: 10.1080/15376516.2017.1422580. Epub 2018 Jan 18. Review.

PMID:
29297242
4.

Recent developments in our understanding of the implications of traditional African medicine on drug metabolism.

Gouws C, Hamman JH.

Expert Opin Drug Metab Toxicol. 2018 Feb;14(2):161-168. doi: 10.1080/17425255.2018.1421171. Epub 2017 Dec 26. Review.

PMID:
29268027
5.

Topical Delivery of Withania somnifera Crude Extracts in Niosomes and Solid Lipid Nanoparticles.

Chinembiri TN, Gerber M, du Plessis LH, du Preez JL, Hamman JH, du Plessis J.

Pharmacogn Mag. 2017 Oct;13(Suppl 3):S663-S671. doi: 10.4103/pm.pm_489_16. Epub 2017 Oct 11.

6.

In vitro wound healing and cytotoxic activity of the gel and whole-leaf materials from selected aloe species.

Fox LT, Mazumder A, Dwivedi A, Gerber M, du Plessis J, Hamman JH.

J Ethnopharmacol. 2017 Mar 22;200:1-7. doi: 10.1016/j.jep.2017.02.017. Epub 2017 Feb 14.

PMID:
28229920
7.

Isolation and in vitro permeation of phenylpropylamino alkaloids from Khat (Catha edulis) across oral and intestinal mucosal tissues.

Atlabachew M, Combrinck S, Viljoen AM, Hamman JH, Gouws C.

J Ethnopharmacol. 2016 Dec 24;194:307-315. doi: 10.1016/j.jep.2016.09.012. Epub 2016 Sep 9.

PMID:
27616032
8.

Combining Chemical Permeation Enhancers for Synergistic Effects.

du Toit T, Malan MM, Lemmer HJ, Gouws C, Aucamp ME, Breytenbach WJ, Hamman JH.

Eur J Drug Metab Pharmacokinet. 2016 Oct;41(5):575-86. doi: 10.1007/s13318-015-0280-7.

PMID:
25939330
9.

Editorial: oral delivery of biotechnology based drugs: dream or reality?

Hamman JH.

Curr Pharm Biotechnol. 2014;15(7):639. No abstract available.

PMID:
25268827
10.

Skin permeation enhancement effects of the gel and whole-leaf materials of Aloe vera, Aloe marlothii and Aloe ferox.

Fox LT, Gerber M, du Preez JL, du Plessis J, Hamman JH.

J Pharm Pharmacol. 2015 Jan;67(1):96-106. doi: 10.1111/jphp.12311. Epub 2014 Sep 5.

PMID:
25196486
11.

Review of natural compounds for potential skin cancer treatment.

Chinembiri TN, du Plessis LH, Gerber M, Hamman JH, du Plessis J.

Molecules. 2014 Aug 6;19(8):11679-721. doi: 10.3390/molecules190811679. Review.

12.

In Vivo skin hydration and anti-erythema effects of Aloe vera, Aloe ferox and Aloe marlothii gel materials after single and multiple applications.

Fox LT, du Plessis J, Gerber M, van Zyl S, Boneschans B, Hamman JH.

Pharmacogn Mag. 2014 Apr;10(Suppl 2):S392-403. doi: 10.4103/0973-1296.133291.

13.

Impact of traditional African medicine on drug metabolism and transport.

Calitz C, Steenekamp JH, Steyn JD, Gouws C, Viljoen JM, Hamman JH.

Expert Opin Drug Metab Toxicol. 2014 Jul;10(7):991-1003. doi: 10.1517/17425255.2014.920321. Epub 2014 May 15. Review.

PMID:
24831257
14.

In vitro evaluation of the cytotoxic and apoptogenic properties of aloe whole leaf and gel materials.

du Plessis LH, Hamman JH.

Drug Chem Toxicol. 2014 Apr;37(2):169-77. doi: 10.3109/01480545.2013.834356. Epub 2013 Oct 11.

PMID:
24111784
15.

Direct compression of chitosan: process and formulation factors to improve powder flow and tablet performance.

Buys GM, du Plessis LH, Marais AF, Kotze AF, Hamman JH.

Curr Drug Deliv. 2013 Jun;10(3):348-56.

PMID:
23545146
16.

Paracellular drug absorption enhancement through tight junction modulation.

Lemmer HJ, Hamman JH.

Expert Opin Drug Deliv. 2013 Jan;10(1):103-14. doi: 10.1517/17425247.2013.745509. Epub 2012 Nov 20. Review.

PMID:
23163247
17.

Permeation of PLGA nanoparticles across different in vitro models.

Nkabinde LA, Shoba-Zikhali LN, Semete-Makokotlela B, Kalombo L, Swai HS, Hayeshi R, Naicker B, Hillie TK, Hamman JH.

Curr Drug Deliv. 2012 Nov;9(6):617-27.

PMID:
22812395
18.

Combination therapy of Western drugs and herbal medicines: recent advances in understanding interactions involving metabolism and efflux.

Gouws C, Steyn D, Du Plessis L, Steenekamp J, Hamman JH.

Expert Opin Drug Metab Toxicol. 2012 Aug;8(8):973-84. doi: 10.1517/17425255.2012.691966. Epub 2012 May 22. Review.

PMID:
22612723
19.

In vitro permeation of mesembrine alkaloids from Sceletium tortuosum across porcine buccal, sublingual, and intestinal mucosa.

Shikanga EA, Hamman JH, Chen W, Combrinck S, Gericke N, Viljoen AM.

Planta Med. 2012 Feb;78(3):260-8. doi: 10.1055/s-0031-1280367. Epub 2011 Nov 21.

PMID:
22105579
20.

Effects of dietary fruits, vegetables and a herbal tea on the in vitro transport of cimetidine: comparing the Caco-2 model with porcine jejunum tissue.

Tarirai C, Viljoen AM, Hamman JH.

Pharm Biol. 2012 Feb;50(2):254-63. doi: 10.3109/13880209.2011.598169.

PMID:
22085278

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