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Items: 1 to 20 of 52

1.

The impact of aging, calorie restriction and dietary fat on mitochondrial ultrastructure, dynamics and autophagy markers in mouse skeletal muscle.

Gutiérrez-Casado E, Khraiwesh H, López-Domínguez JA, Montero-Guisado J, López-Lluch G, Navas P, de Cabo R, Ramsey JJ, González-Reyes JA, Villalba JM.

J Gerontol A Biol Sci Med Sci. 2018 Jul 13. doi: 10.1093/gerona/gly161. [Epub ahead of print]

PMID:
30010806
2.

Regulation of the oxidative balance with coenzyme Q10 sensitizes human glioblastoma cells to radiation and temozolomide.

Frontiñán-Rubio J, Santiago-Mora RM, Nieva-Velasco CM, Ferrín G, Martínez-González A, Gómez MV, Moreno M, Ariza J, Lozano E, Arjona-Gutiérrez J, Gil-Agudo A, De la Mata M, Pesic M, Peinado JR, Villalba JM, Pérez-Romasanta L, Pérez-García VM, Alcaín FJ, Durán-Prado M.

Radiother Oncol. 2018 Aug;128(2):236-244. doi: 10.1016/j.radonc.2018.04.033. Epub 2018 May 18.

PMID:
29784452
3.

Coenzyme Q10: From bench to clinic in aging diseases, a translational review.

Gutierrez-Mariscal FM, Yubero-Serrano EM, Villalba JM, Lopez-Miranda J.

Crit Rev Food Sci Nutr. 2018 Feb 16:1-18. doi: 10.1080/10408398.2018.1442316. [Epub ahead of print]

PMID:
29451807
4.

Protein tyrosine phosphatase 1B deficiency in podocytes mitigates hyperglycemia-induced renal injury.

Ito Y, Hsu MF, Bettaieb A, Koike S, Mello A, Calvo-Rubio M, Villalba JM, Haj FG.

Metabolism. 2017 Nov;76:56-69. doi: 10.1016/j.metabol.2017.07.009. Epub 2017 Aug 8.

PMID:
28987240
5.

Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia.

Bettaieb A, Koike S, Hsu MF, Ito Y, Chahed S, Bachaalany S, Gruzdev A, Calvo-Rubio M, Lee KSS, Inceoglu B, Imig JD, Villalba JM, Zeldin DC, Hammock BD, Haj FG.

Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2758-2765. doi: 10.1016/j.bbagen.2017.07.021. Epub 2017 Jul 27.

PMID:
28757338
6.

Conserved and species-specific molecular denominators in mammalian skeletal muscle aging.

Mercken EM, Capri M, Carboneau BA, Conte M, Heidler J, Santoro A, Martin-Montalvo A, Gonzalez-Freire M, Khraiwesh H, González-Reyes JA, Moaddel R, Zhang Y, Becker KG, Villalba JM, Mattison JA, Wittig I, Franceschi C, de Cabo R.

NPJ Aging Mech Dis. 2017 May 5;3:8. doi: 10.1038/s41514-017-0009-8. eCollection 2017.

7.

Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor.

Fernández-Del-Río L, Nag A, Gutiérrez Casado E, Ariza J, Awad AM, Joseph AI, Kwon O, Verdin E, de Cabo R, Schneider C, Torres JZ, Burón MI, Clarke CF, Villalba JM.

Free Radic Biol Med. 2017 Sep;110:176-187. doi: 10.1016/j.freeradbiomed.2017.06.006. Epub 2017 Jun 9.

8.

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.

Mitchell SJ, Madrigal-Matute J, Scheibye-Knudsen M, Fang E, Aon M, González-Reyes JA, Cortassa S, Kaushik S, Gonzalez-Freire M, Patel B, Wahl D, Ali A, Calvo-Rubio M, Burón MI, Guiterrez V, Ward TM, Palacios HH, Cai H, Frederick DW, Hine C, Broeskamp F, Habering L, Dawson J, Beasley TM, Wan J, Ikeno Y, Hubbard G, Becker KG, Zhang Y, Bohr VA, Longo DL, Navas P, Ferrucci L, Sinclair DA, Cohen P, Egan JM, Mitchell JR, Baur JA, Allison DB, Anson RM, Villalba JM, Madeo F, Cuervo AM, Pearson KJ, Ingram DK, Bernier M, de Cabo R.

Cell Metab. 2016 Jun 14;23(6):1093-1112. doi: 10.1016/j.cmet.2016.05.027.

9.

Dietary fat composition influences glomerular and proximal convoluted tubule cell structure and autophagic processes in kidneys from calorie-restricted mice.

Calvo-Rubio M, Burón MI, López-Lluch G, Navas P, de Cabo R, Ramsey JJ, Villalba JM, González-Reyes JA.

Aging Cell. 2016 Jun;15(3):477-87. doi: 10.1111/acel.12451. Epub 2016 Feb 8.

10.

Olive Oil and the Hallmarks of Aging.

Fernández del Río L, Gutiérrez-Casado E, Varela-López A, Villalba JM.

Molecules. 2016 Jan 29;21(2):163. doi: 10.3390/molecules21020163. Review.

11.

Mediterranean Diet Supplemented With Coenzyme Q10 Modulates the Postprandial Metabolism of Advanced Glycation End Products in Elderly Men and Women.

Lopez-Moreno J, Quintana-Navarro GM, Delgado-Lista J, Garcia-Rios A, Alcala-Diaz JF, Gomez-Delgado F, Camargo A, Perez-Martinez P, Tinahones FJ, Striker GE, Perez-Jimenez F, Villalba JM, Lopez-Miranda J, Yubero-Serrano EM.

J Gerontol A Biol Sci Med Sci. 2018 Mar 2;73(3):340-346. doi: 10.1093/gerona/glw214.

PMID:
28329789
12.

The Influence of Dietary Fat Source on Life Span in Calorie Restricted Mice.

López-Domínguez JA, Ramsey JJ, Tran D, Imai DM, Koehne A, Laing ST, Griffey SM, Kim K, Taylor SL, Hagopian K, Villalba JM, López-Lluch G, Navas P, McDonald RB.

J Gerontol A Biol Sci Med Sci. 2015 Oct;70(10):1181-8. doi: 10.1093/gerona/glu177. Epub 2014 Oct 13.

13.

SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass.

Mercken EM, Mitchell SJ, Martin-Montalvo A, Minor RK, Almeida M, Gomes AP, Scheibye-Knudsen M, Palacios HH, Licata JJ, Zhang Y, Becker KG, Khraiwesh H, González-Reyes JA, Villalba JM, Baur JA, Elliott P, Westphal C, Vlasuk GP, Ellis JL, Sinclair DA, Bernier M, de Cabo R.

Aging Cell. 2014 Oct;13(5):787-96. doi: 10.1111/acel.12220. Epub 2014 Jun 16.

14.

Mitochondrial ultrastructure and markers of dynamics in hepatocytes from aged, calorie restricted mice fed with different dietary fats.

Khraiwesh H, López-Domínguez JA, Fernández del Río L, Gutierrez-Casado E, López-Lluch G, Navas P, de Cabo R, Ramsey JJ, Burón MI, Villalba JM, González-Reyes JA.

Exp Gerontol. 2014 Aug;56:77-88. doi: 10.1016/j.exger.2014.03.023. Epub 2014 Apr 4.

15.

Membrane-bound CYB5R3 is a common effector of nutritional and oxidative stress response through FOXO3a and Nrf2.

Siendones E, SantaCruz-Calvo S, Martín-Montalvo A, Cascajo MV, Ariza J, López-Lluch G, Villalba JM, Acquaviva-Bourdain C, Roze E, Bernier M, de Cabo R, Navas P.

Antioxid Redox Signal. 2014 Oct 20;21(12):1708-25. doi: 10.1089/ars.2013.5479. Epub 2014 Feb 28.

16.

Alterations of ultrastructural and fission/fusion markers in hepatocyte mitochondria from mice following calorie restriction with different dietary fats.

Khraiwesh H, López-Domínguez JA, López-Lluch G, Navas P, de Cabo R, Ramsey JJ, Villalba JM, González-Reyes JA.

J Gerontol A Biol Sci Med Sci. 2013 Sep;68(9):1023-34. doi: 10.1093/gerona/glt006. Epub 2013 Feb 12.

17.

Dietary fat modifies mitochondrial and plasma membrane apoptotic signaling in skeletal muscle of calorie-restricted mice.

López-Domínguez JA, Khraiwesh H, González-Reyes JA, López-Lluch G, Navas P, Ramsey JJ, de Cabo R, Burón MI, Villalba JM.

Age (Dordr). 2013 Dec;35(6):2027-44. doi: 10.1007/s11357-012-9492-9. Epub 2012 Nov 20.

18.

The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction.

Chen Y, Hagopian K, Bibus D, Villalba JM, López-Lluch G, Navas P, Kim K, McDonald RB, Ramsey JJ.

Biosci Rep. 2012 Dec 13;33(1):83-95. doi: 10.1042/BSR20120060.

19.

Sirtuin activators and inhibitors.

Villalba JM, Alcaín FJ.

Biofactors. 2012 Sep-Oct;38(5):349-59. doi: 10.1002/biof.1032. Epub 2012 Jun 25. Review.

20.

The influence of dietary lipid composition on skeletal muscle mitochondria from mice following 1 month of calorie restriction.

Chen Y, Hagopian K, McDonald RB, Bibus D, López-Lluch G, Villalba JM, Navas P, Ramsey JJ.

J Gerontol A Biol Sci Med Sci. 2012 Nov;67(11):1121-31. doi: 10.1093/gerona/gls113. Epub 2012 Apr 13.

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