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Items: 1 to 20 of 39


Immunohistochemical analysis of the expression of cancer-associated fibroblast markers in esophageal cancer with and without neoadjuvant therapy.

Galván JA, Wiprächtiger J, Slotta-Huspenina J, Feith M, Ott K, Kröll D, Seiler CA, Langer R.

Virchows Arch. 2019 Dec 11. doi: 10.1007/s00428-019-02714-6. [Epub ahead of print]


Synaptic proximity enables NMDAR signalling to promote brain metastasis.

Zeng Q, Michael IP, Zhang P, Saghafinia S, Knott G, Jiao W, McCabe BD, Galván JA, Robinson HPC, Zlobec I, Ciriello G, Hanahan D.

Nature. 2019 Sep;573(7775):526-531. doi: 10.1038/s41586-019-1576-6. Epub 2019 Sep 18.


TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells.

Kappel S, Stokłosa P, Hauert B, Ross-Kaschitza D, Borgström A, Baur R, Galván JA, Zlobec I, Peinelt C.

Mol Oncol. 2019 Nov;13(11):2393-2405. doi: 10.1002/1878-0261.12566. Epub 2019 Sep 12.


Cell Line Derived Xenograft Mouse Models Are a Suitable in vivo Model for Studying Tumor Budding in Colorectal Cancer.

Georges LMC, De Wever O, Galván JA, Dawson H, Lugli A, Demetter P, Zlobec I.

Front Med (Lausanne). 2019 Jun 27;6:139. doi: 10.3389/fmed.2019.00139. eCollection 2019.


A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.

Lytle NK, Ferguson LP, Rajbhandari N, Gilroy K, Fox RG, Deshpande A, Schürch CM, Hamilton M, Robertson N, Lin W, Noel P, Wartenberg M, Zlobec I, Eichmann M, Galván JA, Karamitopoulou E, Gilderman T, Esparza LA, Shima Y, Spahn P, French R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik M, Von Hoff D, Han H, Ideker T, Deshpande AJ, Lowy AM, Adams PD, Reya T.

Cell. 2019 Apr 18;177(3):572-586.e22. doi: 10.1016/j.cell.2019.03.010. Epub 2019 Apr 4.


Co-expression of cytokeratin and vimentin in colorectal cancer highlights a subset of tumor buds and an atypical cancer-associated stroma.

Meyer SN, Galván JA, Zahnd S, Sokol L, Dawson H, Lugli A, Zlobec I.

Hum Pathol. 2019 May;87:18-27. doi: 10.1016/j.humpath.2019.02.002. Epub 2019 Feb 20.


Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo.

Basaco T, Pektor S, Bermudez JM, Meneses N, Heller M, Galván JA, Boligán KF, Schürch S, von Gunten S, Türler A, Miederer M.

Pharmaceuticals (Basel). 2018 Nov 28;11(4). pii: E132. doi: 10.3390/ph11040132.


Stromal PD-1/PD-L1 Expression Predicts Outcome in Colon Cancer Patients.

Wyss J, Dislich B, Koelzer VH, Galván JA, Dawson H, Hädrich M, Inderbitzin D, Lugli A, Zlobec I, Berger MD.

Clin Colorectal Cancer. 2019 Mar;18(1):e20-e38. doi: 10.1016/j.clcc.2018.09.007. Epub 2018 Sep 21.


CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway.

Graule J, Uth K, Fischer E, Centeno I, Galván JA, Eichmann M, Rau TT, Langer R, Dawson H, Nitsche U, Traeger P, Berger MD, Schnüriger B, Hädrich M, Studer P, Inderbitzin D, Lugli A, Tschan MP, Zlobec I.

Clin Epigenetics. 2018 Sep 26;10(1):120. doi: 10.1186/s13148-018-0548-2.


GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth.

Li L, Zeng Q, Bhutkar A, Galván JA, Karamitopoulou E, Noordermeer D, Peng MW, Piersigilli A, Perren A, Zlobec I, Robinson H, Iruela-Arispe ML, Hanahan D.

Cancer Cell. 2018 Apr 9;33(4):736-751.e5. doi: 10.1016/j.ccell.2018.02.011. Epub 2018 Mar 29.


Expression Patterns of TNFα, MAdCAM1, and STAT3 in Intestinal and Skin Manifestations of Inflammatory Bowel Disease.

Vavricka SR, Galván JA, Dawson H, Soltermann A, Biedermann L, Scharl M, Schoepfer AM, Rogler G, Prinz Vavricka MB, Terracciano L, Navarini A, Zlobec I, Lugli A, Greuter T.

J Crohns Colitis. 2018 Feb 28;12(3):347-354. doi: 10.1093/ecco-jcc/jjx158.


Androgen production in pediatric adrenocortical tumors may occur via both the classic and/or the alternative backdoor pathway.

Marti N, Malikova J, Galván JA, Aebischer M, Janner M, Sumnik Z, Obermannova B, Escher G, Perren A, Flück CE.

Mol Cell Endocrinol. 2017 Sep 5;452:64-73. doi: 10.1016/j.mce.2017.05.014. Epub 2017 May 10.


Immunohistochemical Detection of the Autophagy Markers LC3 and p62/SQSTM1 in Formalin-Fixed and Paraffin-Embedded Tissue.

Berezowska S, Galván JA.

Methods Mol Biol. 2017;1560:189-194. doi: 10.1007/978-1-4939-6788-9_13.


DNA profiling of tumor buds in colorectal cancer indicates that they have the same mutation profile as the tumor from which they derive.

Centeno I, Paasinen Sohns A, Flury M, Galván JA, Zahnd S, Koelzer VH, Sokol L, Dawson HE, Lugli A, Cathomas G, Zlobec I.

Virchows Arch. 2017 Mar;470(3):341-346. doi: 10.1007/s00428-017-2071-9. Epub 2017 Jan 27. No abstract available.


Glycine decarboxylase and HIF-1α expression are negative prognostic factors in primary resected early-stage non-small cell lung cancer.

Berezowska S, Galván JA, Langer R, Bubendorf L, Savic S, Gugger M, Schmid RA, Marti TM.

Virchows Arch. 2017 Mar;470(3):323-330. doi: 10.1007/s00428-016-2057-z. Epub 2017 Jan 7.


Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer.

Schläfli AM, Adams O, Galván JA, Gugger M, Savic S, Bubendorf L, Schmid RA, Becker KF, Tschan MP, Langer R, Berezowska S.

Oncotarget. 2016 Jun 28;7(26):39544-39555. doi: 10.18632/oncotarget.9647.


PTEN alterations of the stromal cells characterise an aggressive subpopulation of pancreatic cancer with enhanced metastatic potential.

Wartenberg M, Centeno I, Haemmig S, Vassella E, Zlobec I, Galván JA, Neuenschwander M, Schlup C, Gloor B, Lugli A, Perren A, Karamitopoulou E.

Eur J Cancer. 2016 Sep;65:80-90. doi: 10.1016/j.ejca.2016.06.013. Epub 2016 Jul 29.


Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome.

Marti N, Galván JA, Pandey AV, Trippel M, Tapia C, Müller M, Perren A, Flück CE.

Mol Cell Endocrinol. 2017 Feb 5;441:116-123. doi: 10.1016/j.mce.2016.07.029. Epub 2016 Jul 25.


VE1 immunohistochemistry predicts BRAF V600E mutation status and clinical outcome in colorectal cancer.

Schafroth C, Galván JA, Centeno I, Koelzer VH, Dawson HE, Sokol L, Rieger G, Berger MD, Hädrich M, Rosenberg R, Nitsche U, Schnüriger B, Langer R, Inderbitzin D, Lugli A, Zlobec I.

Oncotarget. 2015 Dec 8;6(39):41453-63. doi: 10.18632/oncotarget.6162.


COL11A1/(pro)collagen 11A1 expression is a remarkable biomarker of human invasive carcinoma-associated stromal cells and carcinoma progression.

Vázquez-Villa F, García-Ocaña M, Galván JA, García-Martínez J, García-Pravia C, Menéndez-Rodríguez P, González-del Rey C, Barneo-Serra L, de Los Toyos JR.

Tumour Biol. 2015 Apr;36(4):2213-22. doi: 10.1007/s13277-015-3295-4. Epub 2015 Mar 12. Review.


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