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Items: 19


Microfluidic platform for electrophysiological recordings from host-stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research.

Weeks JC, Roberts WM, Robinson KJ, Keaney M, Vermeire JJ, Urban JF Jr, Lockery SR, Hawdon JM.

Int J Parasitol Drugs Drug Resist. 2016 Dec;6(3):314-328. doi: 10.1016/j.ijpddr.2016.08.001. Epub 2016 Sep 15.


Odanacatib, a Cathepsin K Cysteine Protease Inhibitor, Kills Hookworm In Vivo.

Vermeire JJ, Suzuki BM, Caffrey CR.

Pharmaceuticals (Basel). 2016 Jul 4;9(3). pii: E39. doi: 10.3390/ph9030039.


In vitro screening of compounds against laboratory and field isolates of human hookworm reveals quantitative differences in anthelmintic susceptibility.

Treger RS, Otchere J, Keil MF, Quagraine JE, Rai G, Mott BT, Humphries DL, Wilson M, Cappello M, Vermeire JJ.

Am J Trop Med Hyg. 2014 Jan;90(1):71-4. doi: 10.4269/ajtmh.12-0547. Epub 2013 Dec 2.


Characterization of the phytochelatin synthase from the human parasitic nematode Ancylostoma ceylanicum.

Rigouin C, Vermeire JJ, Nylin E, Williams DL.

Mol Biochem Parasitol. 2013 Sep;191(1):1-6. doi: 10.1016/j.molbiopara.2013.07.003. Epub 2013 Jul 31.


Peroxiredoxin-1 from the human hookworm Ancylostoma ceylanicum forms a stable oxidized decamer and is covalently inhibited by conoidin A.

Nguyen JB, Pool CD, Wong CY, Treger RS, Williams DL, Cappello M, Lea WA, Simeonov A, Vermeire JJ, Modis Y.

Chem Biol. 2013 Aug 22;20(8):991-1001. doi: 10.1016/j.chembiol.2013.06.011. Epub 2013 Jul 25.


Frequency and intensity of exposure mediate resistance to experimental infection with the hookworm, Ancylostoma ceylanicum.

Davey D, Manickam N, Simms BT, Harrison LM, Vermeire JJ, Cappello M.

Exp Parasitol. 2013 Mar;133(3):243-9. doi: 10.1016/j.exppara.2012.11.010. Epub 2012 Dec 8.


A furoxan-amodiaquine hybrid as a potential therapeutic for three parasitic diseases().

Mott BT, Cheng KC, Guha R, Kommer VP, Williams DL, Vermeire JJ, Cappello M, Maloney DJ, Rai G, Jadhav A, Simeonov A, Inglese J, Posner GH, Thomas CJ.

Medchemcomm. 2012 Dec;3(12):1505-1511.


Cure of hookworm infection with a cysteine protease inhibitor.

Vermeire JJ, Lantz LD, Caffrey CR.

PLoS Negl Trop Dis. 2012;6(7):e1680. doi: 10.1371/journal.pntd.0001680. Epub 2012 Jul 3.


Drug repositioning and pharmacophore identification in the discovery of hookworm MIF inhibitors.

Cho Y, Vermeire JJ, Merkel JS, Leng L, Du X, Bucala R, Cappello M, Lolis E.

Chem Biol. 2011 Sep 23;18(9):1089-101. doi: 10.1016/j.chembiol.2011.07.011.


Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.

Cho Y, Crichlow GV, Vermeire JJ, Leng L, Du X, Hodsdon ME, Bucala R, Cappello M, Gross M, Gaeta F, Johnson K, Lolis EJ.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11313-8. doi: 10.1073/pnas.1002716107. Epub 2010 Jun 8.


Characterisation of a fatty acid and retinol binding protein orthologue from the hookworm Ancylostoma ceylanicum.

Fairfax KC, Vermeire JJ, Harrison LM, Bungiro RD, Grant W, Husain SZ, Cappello M.

Int J Parasitol. 2009 Dec;39(14):1561-71. doi: 10.1016/j.ijpara.2009.06.005. Epub 2009 Jul 8.


Developmental expression analysis and immunolocalization of a biogenic amine receptor in Schistosoma mansoni.

El-Shehabi F, Vermeire JJ, Yoshino TP, Ribeiro P.

Exp Parasitol. 2009 May;122(1):17-27. doi: 10.1016/j.exppara.2009.01.001. Epub 2009 Jan 20.


Orthologs of macrophage migration inhibitory factor from parasitic nematodes.

Vermeire JJ, Cho Y, Lolis E, Bucala R, Cappello M.

Trends Parasitol. 2008 Aug;24(8):355-63. doi: 10.1016/ Epub 2008 Jul 4. Review.


Role for nitric oxide in hookworm-associated immune suppression.

Dondji B, Bungiro RD, Harrison LM, Vermeire JJ, Bifulco C, McMahon-Pratt D, Cappello M.

Infect Immun. 2008 Jun;76(6):2560-7. doi: 10.1128/IAI.00094-08. Epub 2008 Mar 17.


Profiling Schistosoma mansoni development using serial analysis of gene expression (SAGE).

Williams DL, Sayed AA, Bernier J, Birkeland SR, Cipriano MJ, Papa AR, McArthur AG, Taft A, Vermeire JJ, Yoshino TP.

Exp Parasitol. 2007 Nov;117(3):246-58. Epub 2007 May 13.


Structural and functional characterization of a secreted hookworm Macrophage Migration Inhibitory Factor (MIF) that interacts with the human MIF receptor CD74.

Cho Y, Jones BF, Vermeire JJ, Leng L, DiFedele L, Harrison LM, Xiong H, Kwong YK, Chen Y, Bucala R, Lolis E, Cappello M.

J Biol Chem. 2007 Aug 10;282(32):23447-56. Epub 2007 Jun 13.


Schistosoma mansoni: DNA microarray gene expression profiling during the miracidium-to-mother sporocyst transformation.

Vermeire JJ, Taft AS, Hoffmann KF, Fitzpatrick JM, Yoshino TP.

Mol Biochem Parasitol. 2006 May;147(1):39-47. Epub 2006 Feb 2.


Differential gene expression and the effects of Biomphalaria glabrata embryonic (Bge) cell factors during larval Schistosoma mansoni development.

Vermeire JJ, Boyle JP, Yoshino TP.

Mol Biochem Parasitol. 2004 May;135(1):153-7. No abstract available.


Characterisation of a Rho homologue of Schistosoma mansoni.

Vermeire JJ, Osman A, LoVerde PT, Williams DL.

Int J Parasitol. 2003 Jul;33(7):721-31.


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