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Items: 1 to 20 of 165

1.

Role of mitochondrial depolarization and disrupted mitochondrial homeostasis in non-alcoholic steatohepatitis and fibrosis in mice.

Krishnasamy Y, Gooz M, Li L, Lemasters JJ, Zhong Z.

Int J Physiol Pathophysiol Pharmacol. 2019 Oct 15;11(5):190-204. eCollection 2019.

2.

Aldehyde dehydrogenase-2 activation by Alda-1 decreases necrosis and fibrosis after bile duct ligation in mice.

Wimborne HJ, Takemoto K, Woster PM, Rockey DC, Lemasters JJ, Zhong Z.

Free Radic Biol Med. 2019 Dec;145:136-145. doi: 10.1016/j.freeradbiomed.2019.09.026. Epub 2019 Sep 23.

PMID:
31557514
3.

Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress.

Oleinik N, Kim J, Roth BM, Selvam SP, Gooz M, Johnson RH, Lemasters JJ, Ogretmen B.

Sci Adv. 2019 Sep 11;5(9):eaax1978. doi: 10.1126/sciadv.aax1978. eCollection 2019 Sep.

4.

Mitophagy in hepatocytes: Types, initiators and role in adaptive ethanol metabolism☆.

Lemasters JJ, Zhong Z.

Liver Res. 2018 Sep;2(3):125-132. doi: 10.1016/j.livres.2018.09.005. Epub 2018 Sep 20.

5.

A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome.

Jing R, Corbett JL, Cai J, Beeson GC, Beeson CC, Chan SS, Dimmock DP, Lazcares L, Geurts AM, Lemasters JJ, Duncan SA.

Cell Rep. 2018 Nov 6;25(6):1469-1484.e5. doi: 10.1016/j.celrep.2018.10.036.

6.

A Unifying Hypothesis Linking Hepatic Adaptations for Ethanol Metabolism to the Proinflammatory and Profibrotic Events of Alcoholic Liver Disease.

Zhong Z, Lemasters JJ.

Alcohol Clin Exp Res. 2018 Nov;42(11):2072-2089. doi: 10.1111/acer.13877. Epub 2018 Sep 17. Review.

7.

The role of mitochondrial KATP channel in anti-inflammatory effects of uridine in endotoxemic mice.

Mironova GD, Khrenov MO, Talanov EY, Glushkova OV, Parfenyuk SB, Novoselova TV, Lunin SM, Belosludtseva NV, Novoselova EG, Lemasters JJ.

Arch Biochem Biophys. 2018 Sep 15;654:70-76. doi: 10.1016/j.abb.2018.07.006. Epub 2018 Jul 20.

PMID:
30009781
8.

Imaging of Mitochondrial pH Using SNARF-1.

Ramshesh VK, Lemasters JJ.

Methods Mol Biol. 2018;1782:351-356. doi: 10.1007/978-1-4939-7831-1_21.

PMID:
29851011
9.

Ischemic preconditioning attenuates acute lung injury after partial liver transplantation.

Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z.

Int J Physiol Pathophysiol Pharmacol. 2018 Apr 20;10(2):83-94. eCollection 2018.

10.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

11.

Editorial: Uncovering the Function of the Mitochondrial Protein VDAC in Health and Disease: From Structure-Function to Novel Therapeutic Strategies.

Shoshan-Barmatz V, Kmita H, Lemasters JJ.

Front Oncol. 2017 Dec 22;7:320. doi: 10.3389/fonc.2017.00320. eCollection 2017. No abstract available.

12.

Evolution of Voltage-Dependent Anion Channel Function: From Molecular Sieve to Governator to Actuator of Ferroptosis.

Lemasters JJ.

Front Oncol. 2017 Dec 19;7:303. doi: 10.3389/fonc.2017.00303. eCollection 2017.

13.

Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells.

DeHart DN, Fang D, Heslop K, Li L, Lemasters JJ, Maldonado EN.

Biochem Pharmacol. 2018 Feb;148:155-162. doi: 10.1016/j.bcp.2017.12.022. Epub 2017 Dec 28.

14.

Acid sphingomyelinase promotes mitochondrial dysfunction due to glutamate-induced regulated necrosis.

Novgorodov SA, Voltin JR, Gooz MA, Li L, Lemasters JJ, Gudz TI.

J Lipid Res. 2018 Feb;59(2):312-329. doi: 10.1194/jlr.M080374. Epub 2017 Dec 27.

15.

HDAC1 localizes to the mitochondria of cardiac myocytes and contributes to early cardiac reperfusion injury.

Herr DJ, Baarine M, Aune SE, Li X, Ball LE, Lemasters JJ, Beeson CC, Chou JC, Menick DR.

J Mol Cell Cardiol. 2018 Jan;114:309-319. doi: 10.1016/j.yjmcc.2017.12.004. Epub 2017 Dec 7.

16.

ATP/ADP turnover and import of glycolytic ATP into mitochondria in cancer cells is independent of the adenine nucleotide translocator.

Maldonado EN, DeHart DN, Patnaik J, Klatt SC, Gooz MB, Lemasters JJ.

J Biol Chem. 2017 Oct 13;292(41):16969. doi: 10.1074/jbc.A116.734814. No abstract available.

17.

Erastin-Like Anti-Warburg Agents Prevent Mitochondrial Depolarization Induced by Free Tubulin and Decrease Lactate Formation in Cancer Cells.

DeHart DN, Lemasters JJ, Maldonado EN.

SLAS Discov. 2018 Jan;23(1):23-33. doi: 10.1177/2472555217731556. Epub 2017 Oct 12.

18.

8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation.

Liu Q, Rehman H, Krishnasamy Y, Lemasters JJ, Zhong Z.

Int J Physiol Pathophysiol Pharmacol. 2017 Jun 15;9(3):69-83. eCollection 2017.

19.

Glutamate contributes to alcohol hepatotoxicity by enhancing oxidative stress in mitochondria.

Teplova VV, Kruglov AG, Kovalyov LI, Nikiforova AB, Fedotcheva NI, Lemasters JJ.

J Bioenerg Biomembr. 2017 Jun;49(3):253-264. doi: 10.1007/s10863-017-9713-0. Epub 2017 May 6.

20.

Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire.

Lemasters JJ, Ramshesh VK, Lovelace GL, Lim J, Wright GD, Harland D, Dawson TL Jr.

J Invest Dermatol. 2017 Jul;137(7):1434-1444. doi: 10.1016/j.jid.2017.02.983. Epub 2017 Mar 23.

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