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Items: 1 to 20 of 47

1.

Protective effects of novel derivatives of vitamin D3 and lumisterol against UVB-induced damage in human keratinocytes involve activation of Nrf2 and p53 defense mechanisms.

Chaiprasongsuk A, Janjetovic Z, Kim TK, Jarrett SG, D'Orazio JA, Holick MF, Tang EKY, Tuckey RC, Panich U, Li W, Slominski AT.

Redox Biol. 2019 Apr 20;24:101206. doi: 10.1016/j.redox.2019.101206. [Epub ahead of print]

2.

cAMP-mediated regulation of melanocyte genomic instability: A melanoma-preventive strategy.

Holcomb NC, Bautista RM, Jarrett SG, Carter KM, Gober MK, D'Orazio JA.

Adv Protein Chem Struct Biol. 2019;115:247-295. doi: 10.1016/bs.apcsb.2018.10.008. Epub 2018 Dec 5.

PMID:
30798934
3.

Sirtuin 1-mediated deacetylation of XPA DNA repair protein enhances its interaction with ATR protein and promotes cAMP-induced DNA repair of UV damage.

Jarrett SG, Carter KM, Bautista RM, He D, Wang C, D'Orazio JA.

J Biol Chem. 2018 Dec 7;293(49):19025-19037. doi: 10.1074/jbc.RA118.003940. Epub 2018 Oct 16.

PMID:
30327428
4.

Frontiers in pigment cell and melanoma research.

Filipp FV, Birlea S, Bosenberg MW, Brash D, Cassidy PB, Chen S, D'Orazio JA, Fujita M, Goh BK, Herlyn M, Indra AK, Larue L, Leachman SA, Le Poole C, Liu-Smith F, Manga P, Montoliu L, Norris DA, Shellman Y, Smalley KSM, Spritz RA, Sturm RA, Swetter SM, Terzian T, Wakamatsu K, Weber JS, Box NF.

Pigment Cell Melanoma Res. 2018 Nov;31(6):728-735. doi: 10.1111/pcmr.12728. Epub 2018 Oct 3.

5.

The melanocortin signaling cAMP axis accelerates repair and reduces mutagenesis of platinum-induced DNA damage.

Jarrett SG, Carter KM, Shelton BJ, D'Orazio JA.

Sci Rep. 2017 Sep 15;7(1):11708. doi: 10.1038/s41598-017-12056-5.

6.

Getting a tan without getting SIK.

D'Orazio JA.

Pigment Cell Melanoma Res. 2017 Sep;30(5):451-453. doi: 10.1111/pcmr.12613. No abstract available.

PMID:
28677151
7.

Inorganic arsenic inhibits the nucleotide excision repair pathway and reduces the expression of XPC.

Holcomb N, Goswami M, Han SG, Scott T, D'Orazio J, Orren DK, Gairola CG, Mellon I.

DNA Repair (Amst). 2017 Apr;52:70-80. doi: 10.1016/j.dnarep.2017.02.009. Epub 2017 Feb 16.

8.

Paracrine regulation of melanocyte genomic stability: a focus on nucleotide excision repair.

Jarrett SG, Carter KM, D'Orazio JA.

Pigment Cell Melanoma Res. 2017 May;30(3):284-293. doi: 10.1111/pcmr.12582. Epub 2017 Apr 20. Review.

9.

Divergence of cAMP signalling pathways mediating augmented nucleotide excision repair and pigment induction in melanocytes.

Wolf Horrell EM, Jarrett SG, Carter KM, D'Orazio JA.

Exp Dermatol. 2017 Jul;26(7):577-584. doi: 10.1111/exd.13291. Epub 2017 Apr 21.

10.

AKAP12 mediates PKA-induced phosphorylation of ATR to enhance nucleotide excision repair.

Jarrett SG, Wolf Horrell EM, D'Orazio JA.

Nucleic Acids Res. 2016 Dec 15;44(22):10711-10726. Epub 2016 Sep 28.

11.

Hormonal Regulation of the Repair of UV Photoproducts in Melanocytes by the Melanocortin Signaling Axis.

Jarrett SG, D'Orazio JA.

Photochem Photobiol. 2017 Jan;93(1):245-258. doi: 10.1111/php.12640. Epub 2016 Nov 17. Review.

12.

Venous Thromboembolic Disease in Children and Adolescents.

Radulescu VC, D'Orazio JA.

Adv Exp Med Biol. 2017;906:149-165. Review.

PMID:
27628011
13.

Melanocortin 1 Receptor: Structure, Function, and Regulation.

Wolf Horrell EM, Boulanger MC, D'Orazio JA.

Front Genet. 2016 May 31;7:95. doi: 10.3389/fgene.2016.00095. eCollection 2016. Review.

14.

Defining the Contribution of MC1R Physiological Ligands to ATR Phosphorylation at Ser435, a Predictor of DNA Repair in Melanocytes.

Jarrett SG, Wolf Horrell EM, Boulanger MC, D'Orazio JA.

J Invest Dermatol. 2015 Dec;135(12):3086-3095. doi: 10.1038/jid.2015.280. Epub 2015 Jul 13.

15.

Melanocyte UV resistance: Feelin' the endothelin.

D'Orazio JA.

Exp Dermatol. 2015 Jun;24(6):414-5. doi: 10.1111/exd.12663. Epub 2015 Apr 16. No abstract available.

PMID:
25683271
16.

UV-independent induction of beta defensin 3 in neonatal human skin explants.

Wolf Horrell E, D'Orazio J.

Version 2. F1000Res. 2014 Nov 21 [revised 2015 Jan 1];3:288. doi: 10.12688/f1000research.5794.2. eCollection 2014.

17.

Pheochromocytoma in a Twelve-Year-Old Girl with SDHB-Related Hereditary Paraganglioma-Pheochromocytoma Syndrome.

Graham D, Gooch M, Ye Z, Richer E, Chishti A, Reilly E, D'Orazio J.

Case Rep Genet. 2014;2014:273423. doi: 10.1155/2014/273423. Epub 2014 Aug 19.

18.

Dyskeratosis congenita caused by a novel TERT point mutation in siblings with pancytopenia and exudative retinopathy.

Sharma A, Myers K, Ye Z, D'Orazio J.

Pediatr Blood Cancer. 2014 Dec;61(12):2302-4. doi: 10.1002/pbc.25161. Epub 2014 Jul 25.

19.

PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.

Jarrett SG, Wolf Horrell EM, Christian PA, Vanover JC, Boulanger MC, Zou Y, D'Orazio JA.

Mol Cell. 2014 Jun 19;54(6):999-1011. doi: 10.1016/j.molcel.2014.05.030.

20.

Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipulation.

Amaro-Ortiz A, Yan B, D'Orazio JA.

Molecules. 2014 May 15;19(5):6202-19. doi: 10.3390/molecules19056202. Review.

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