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Items: 1 to 20 of 141


Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats.

Jerkic M, Gagnon S, Rabani R, Ward-Able T, Masterson C, Otulakowski G, Curley GF, Marshall J, Kavanagh BP, Laffey JG.

Anesthesiology. 2020 Jan;132(1):140-154. doi: 10.1097/ALN.0000000000003018.


Accuracy of pediatric cricothyroid membrane identification by digital palpation and implications for emergency front of neck access.

Fennessy P, Walsh B, Laffey JG, McCarthy KF, McCaul CL.

Paediatr Anaesth. 2020 Jan;30(1):69-77. doi: 10.1111/pan.13773. Epub 2019 Dec 4.


Nebulized Mesenchymal Stem Cell Derived Conditioned Medium Retains Antibacterial Properties Against Clinical Pathogen Isolates.

McCarthy SD, Horgan E, Ali A, Masterson C, Laffey JG, MacLoughlin R, O'Toole D.

J Aerosol Med Pulm Drug Deliv. 2019 Nov 15. doi: 10.1089/jamp.2019.1542. [Epub ahead of print]


What's new in airway management of the critically ill.

Russotto V, Myatra SN, Laffey JG.

Intensive Care Med. 2019 Nov;45(11):1615-1618. doi: 10.1007/s00134-019-05757-0. Epub 2019 Sep 16. No abstract available.


Modulating the distribution and fate of exogenously delivered MSCs to enhance therapeutic potential: knowns and unknowns.

Masterson CH, Curley GF, Laffey JG.

Intensive Care Med Exp. 2019 Jul 25;7(Suppl 1):41. doi: 10.1186/s40635-019-0235-4. Review.


Demographics, management and outcome of females and males with acute respiratory distress syndrome in the LUNG SAFE prospective cohort study.

McNicholas BA, Madotto F, Pham T, Rezoagli E, Masterson CH, Horie S, Bellani G, Brochard L, Laffey JG; LUNG SAFE Investigators and the ESICM Trials Group.

Eur Respir J. 2019 Oct 17;54(4). pii: 1900609. doi: 10.1183/13993003.00609-2019. Print 2019 Oct.


Overexpression of IL-10 Enhances the Efficacy of Human Umbilical-Cord-Derived Mesenchymal Stromal Cells in E. coli Pneumosepsis.

Jerkic M, Masterson C, Ormesher L, Gagnon S, Goyal S, Rabani R, Otulakowski G, Zhang H, Kavanagh BP, Laffey JG.

J Clin Med. 2019 Jun 13;8(6). pii: E847. doi: 10.3390/jcm8060847.


Impact of Early Acute Kidney Injury on Management and Outcome in Patients With Acute Respiratory Distress Syndrome: A Secondary Analysis of a Multicenter Observational Study.

McNicholas BA, Rezoagli E, Pham T, Madotto F, Guiard E, Fanelli V, Bellani G, Griffin MD, Ranieri M, Laffey JG; ESICM Trials Group and the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) Investigators.

Crit Care Med. 2019 Sep;47(9):1216-1225. doi: 10.1097/CCM.0000000000003832.


The worldwide assessment of separation of patients from ventilatory assistance (WEAN SAFE) ERS Clinical Research Collaboration.

Heunks L, Bellani G, Pham T, Brochard L, Laffey JG.

Eur Respir J. 2019 Mar 18;53(3). pii: 1802228. doi: 10.1183/13993003.02228-2018. Print 2019 Mar. No abstract available.


Extracellular Vesicles from Interferon-γ-primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli-induced Acute Lung Injury in Rats.

Varkouhi AK, Jerkic M, Ormesher L, Gagnon S, Goyal S, Rabani R, Masterson C, Spring C, Chen PZ, Gu FX, Dos Santos CC, Curley GF, Laffey JG.

Anesthesiology. 2019 May;130(5):778-790. doi: 10.1097/ALN.0000000000002655.


Declining Mortality in Patients With Acute Respiratory Distress Syndrome: An Analysis of the Acute Respiratory Distress Syndrome Network Trials.

Zhang Z, Spieth PM, Chiumello D, Goyal H, Torres A, Laffey JG, Hong Y.

Crit Care Med. 2019 Mar;47(3):315-323. doi: 10.1097/CCM.0000000000003499.


Cell therapy in acute respiratory distress syndrome.

Horie S, Gonzalez HE, Laffey JG, Masterson CH.

J Thorac Dis. 2018 Sep;10(9):5607-5620. doi: 10.21037/jtd.2018.08.28. Review.


Is Activity Tracker-Measured Ambulation an Accurate and Reliable Determinant of Postoperative Quality of Recovery? A Prospective Cohort Validation Study.

Massouh F, Martin R, Chan B, Ma J, Patel V, Geary MP, Laffey JG, Wijeysundera DN, Abdallah FW.

Anesth Analg. 2019 Oct;129(4):1144-1152. doi: 10.1213/ANE.0000000000003913.


Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study.

van Haren F, Pham T, Brochard L, Bellani G, Laffey J, Dres M, Fan E, Goligher EC, Heunks L, Lynch J, Wrigge H, McAuley D; Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) Investigators.

Crit Care Med. 2019 Feb;47(2):229-238. doi: 10.1097/CCM.0000000000003519.


Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database.

Boyle AJ, Madotto F, Laffey JG, Bellani G, Pham T, Pesenti A, Thompson BT, O'Kane CM, Deane AM, McAuley DF; LUNG SAFE Investigators; ESICM Trials Group.

Crit Care. 2018 Oct 27;22(1):268. doi: 10.1186/s13054-018-2158-y.


Recommended Reading from the Galway University Hospitals, Department of Anaesthesia and Intensive Care Medicine Fellows.

Rezoagli E, McNicholas B, Moran P, Laffey JG.

Am J Respir Crit Care Med. 2018 Oct 2. doi: 10.1164/rccm.201804-0782RR. [Epub ahead of print] No abstract available.


Human Mesenchymal Stem Cell Secretome from Bone Marrow or Adipose-Derived Tissue Sources for Treatment of Hypoxia-Induced Pulmonary Epithelial Injury.

Shologu N, Scully M, Laffey JG, O'Toole D.

Int J Mol Sci. 2018 Sep 30;19(10). pii: E2996. doi: 10.3390/ijms19102996.


Sepsis: Therapeutic Potential of Immunosuppression versus Immunostimulation.

Rezoagli E, Masterson CH, McCarthy SD, Laffey JG.

Am J Respir Cell Mol Biol. 2019 Jan;60(1):128-130. doi: 10.1165/rcmb.2018-0284RO. No abstract available.


Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries.

Abe T, Madotto F, Pham T, Nagata I, Uchida M, Tamiya N, Kurahashi K, Bellani G, Laffey JG; LUNG-SAFE Investigators and the ESICM Trials Group.

Crit Care. 2018 Aug 17;22(1):195. doi: 10.1186/s13054-018-2126-6.


Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial.

Calfee CS, Delucchi KL, Sinha P, Matthay MA, Hackett J, Shankar-Hari M, McDowell C, Laffey JG, O'Kane CM, McAuley DF; Irish Critical Care Trials Group.

Lancet Respir Med. 2018 Sep;6(9):691-698. doi: 10.1016/S2213-2600(18)30177-2. Epub 2018 Aug 2.

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