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NRF2 activation with Protandim attenuates salt-induced vascular dysfunction and microvascular rarefaction.

Priestley JRC, Fink KE, McCord JM, Lombard JH.

Microcirculation. 2019 May 27:e12575. doi: 10.1111/micc.12575. [Epub ahead of print]


MiR-144 mediates Nrf2 inhibition and alveolar epithelial dysfunction in HIV-1 transgenic rats.

Kukoyi AT, Fan X, Staitieh BS, Hybertson BM, Gao B, McCord JM, Guidot DM.

Am J Physiol Cell Physiol. 2019 May 15. doi: 10.1152/ajpcell.00038.2019. [Epub ahead of print]


Phytochemical Combination PB125 Activates the Nrf2 Pathway and Induces Cellular Protection against Oxidative Injury.

Hybertson BM, Gao B, Bose S, McCord JM.

Antioxidants (Basel). 2019 May 3;8(5). pii: E119. doi: 10.3390/antiox8050119.


Hypoxia compounds exercise-induced free radical formation in humans; partitioning contributions from the cerebral and femoral circulation.

Bailey DM, Rasmussen P, Evans KA, Bohm AM, Zaar M, Nielsen HB, Brassard P, Nordsborg NB, Homann PH, Raven PB, McEneny J, Young IS, McCord JM, Secher NH.

Free Radic Biol Med. 2018 Aug 20;124:104-113. doi: 10.1016/j.freeradbiomed.2018.05.090. Epub 2018 May 31.


Protandim Protects Oligodendrocytes against an Oxidative Insult.

Lim JL, van der Pol SM, Baron W, McCord JM, de Vries HE, van Horssen J.

Antioxidants (Basel). 2016 Sep 7;5(3). pii: E30. doi: 10.3390/antiox5030030.


Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.

Strong R, Miller RA, Antebi A, Astle CM, Bogue M, Denzel MS, Fernandez E, Flurkey K, Hamilton KL, Lamming DW, Javors MA, de Magalhães JP, Martinez PA, McCord JM, Miller BF, Müller M, Nelson JF, Ndukum J, Rainger GE, Richardson A, Sabatini DM, Salmon AB, Simpkins JW, Steegenga WT, Nadon NL, Harrison DE.

Aging Cell. 2016 Oct;15(5):872-84. doi: 10.1111/acel.12496. Epub 2016 Jun 16.


Superoxide dismutases: you've come a long way, baby.

McCord JM, Fridovich I.

Antioxid Redox Signal. 2014 Apr 1;20(10):1548-9. doi: 10.1089/ars.2013.5547. Epub 2013 Sep 11. No abstract available.


The role of Nrf2 in the attenuation of cardiovascular disease.

Reuland DJ, McCord JM, Hamilton KL.

Exerc Sport Sci Rev. 2013 Jul;41(3):162-8. doi: 10.1097/JES.0b013e3182948a1e. Review.


Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress.

Reuland DJ, Khademi S, Castle CJ, Irwin DC, McCord JM, Miller BF, Hamilton KL.

Free Radic Biol Med. 2013 Mar;56:102-11. doi: 10.1016/j.freeradbiomed.2012.11.016. Epub 2012 Nov 30.


Phytochemical activation of Nrf2 protects human coronary artery endothelial cells against an oxidative challenge.

Donovan EL, McCord JM, Reuland DJ, Miller BF, Hamilton KL.

Oxid Med Cell Longev. 2012;2012:132931. doi: 10.1155/2012/132931. Epub 2012 May 22.


Protandim does not influence alveolar epithelial permeability or intrapulmonary oxidative stress in human subjects with alcohol use disorders.

Burnham EL, McCord JM, Bose S, Brown LA, House R, Moss M, Gaydos J.

Am J Physiol Lung Cell Mol Physiol. 2012 Apr 1;302(7):L688-99. doi: 10.1152/ajplung.00297.2011. Epub 2012 Jan 20.


Potential role for elevated maternal enzymatic antioxidant status in Andean protection against altitude-associated SGA.

Julian CG, Vargas E, Browne VA, Wilson MJ, Bigham AW, Rodriguez C, McCord JM, Moore LG.

J Matern Fetal Neonatal Med. 2012 Aug;25(8):1233-40. doi: 10.3109/14767058.2011.636102. Epub 2011 Nov 30.


Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation.

Hybertson BM, Gao B, Bose SK, McCord JM.

Mol Aspects Med. 2011 Aug;32(4-6):234-46. doi: 10.1016/j.mam.2011.10.006. Epub 2011 Oct 15. Review.


2',5'-Dihydroxychalcone-induced glutathione is mediated by oxidative stress and kinase signaling pathways.

Kachadourian R, Pugazhenthi S, Velmurugan K, Backos DS, Franklin CC, McCord JM, Day BJ.

Free Radic Biol Med. 2011 Sep 15;51(6):1146-54. doi: 10.1016/j.freeradbiomed.2011.05.041. Epub 2011 Jun 13.


Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway.

Joddar B, Reen RK, Firstenberg MS, Varadharaj S, McCord JM, Zweier JL, Gooch KJ.

Free Radic Biol Med. 2011 Mar 15;50(6):700-9. doi: 10.1016/j.freeradbiomed.2010.12.008. Epub 2010 Dec 15.


Sustained lung activity of a novel chimeric protein, SOD2/3, after intratracheal administration.

Clarke MB, Wright R, Irwin D, Bose S, Van Rheen Z, Birari R, Stenmark KR, McCord JM, Nozik-Grayck E.

Free Radic Biol Med. 2010 Dec 15;49(12):2032-9. doi: 10.1016/j.freeradbiomed.2010.09.028. Epub 2010 Oct 4.


The Dietary Supplement Protandim Decreases Plasma Osteopontin and Improves Markers of Oxidative Stress in Muscular Dystrophy Mdx Mice.

Qureshi MM, McClure WC, Arevalo NL, Rabon RE, Mohr B, Bose SK, McCord JM, Tseng BS.

J Diet Suppl. 2010 Jun 1;7(2):159-178.


The chemopreventive effects of Protandim: modulation of p53 mitochondrial translocation and apoptosis during skin carcinogenesis.

Robbins D, Gu X, Shi R, Liu J, Wang F, Ponville J, McCord JM, Zhao Y.

PLoS One. 2010 Jul 30;5(7):e11902. doi: 10.1371/journal.pone.0011902.


Sedentary aging increases resting and exercise-induced intramuscular free radical formation.

Bailey DM, McEneny J, Mathieu-Costello O, Henry RR, James PE, McCord JM, Pietri S, Young IS, Richardson RS.

J Appl Physiol (1985). 2010 Aug;109(2):449-56. doi: 10.1152/japplphysiol.00354.2010. Epub 2010 May 27.


Thiol-sensitive mutant forms of human SOD2, L60F, and I58T: the role of Cys140.

Hernandez-Saavedra D, Quijano C, Demicheli V, Souza JM, Radi R, McCord JM.

Free Radic Biol Med. 2010 May 1;48(9):1202-10. doi: 10.1016/j.freeradbiomed.2010.02.001. Epub 2010 Feb 6.


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