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Items: 1 to 20 of 27


A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice.

Plas RLC, Poland M, Faber J, Argilès J, van Dijk M, Laviano A, Meijerink J, Witkamp RF, van Helvoort A, van Norren K.

Int J Mol Sci. 2019 Oct 9;20(20). pii: E4978. doi: 10.3390/ijms20204978.


N-Eicosapentaenoyl Dopamine, A Conjugate of Dopamine and Eicosapentaenoic Acid (EPA), Exerts Anti-inflammatory Properties in Mouse and Human Macrophages.

Augimeri G, Plastina P, Gionfriddo G, Rovito D, Giordano C, Fazio A, Barone I, Catalano S, Andò S, Bonofiglio D, Meijerink J, Witkamp R.

Nutrients. 2019 Sep 18;11(9). pii: E2247. doi: 10.3390/nu11092247.


Capsaicin Analogues Derived from n-3 Polyunsaturated Fatty Acids (PUFAs) Reduce Inflammatory Activity of Macrophages and Stimulate Insulin Secretion by β-Cells In Vitro.

Cione E, Plastina P, Pingitore A, Perri M, Caroleo MC, Fazio A, Witkamp R, Meijerink J.

Nutrients. 2019 Apr 24;11(4). pii: E915. doi: 10.3390/nu11040915.


Identification of hydroxytyrosyl oleate, a derivative of hydroxytyrosol with anti-inflammatory properties, in olive oil by-products.

Plastina P, Benincasa C, Perri E, Fazio A, Augimeri G, Poland M, Witkamp R, Meijerink J.

Food Chem. 2019 May 1;279:105-113. doi: 10.1016/j.foodchem.2018.12.007. Epub 2018 Dec 6.


Mitochondrial dynamics in cancer-induced cachexia.

van der Ende M, Grefte S, Plas R, Meijerink J, Witkamp RF, Keijer J, van Norren K.

Biochim Biophys Acta Rev Cancer. 2018 Dec;1870(2):137-150. doi: 10.1016/j.bbcan.2018.07.008. Epub 2018 Jul 29. Review.


In Vitro Anti-Inflammatory and Radical Scavenging Properties of Chinotto (Citrus myrtifolia Raf.) Essential Oils.

Plastina P, Apriantini A, Meijerink J, Witkamp R, Gabriele B, Fazio A.

Nutrients. 2018 Jun 18;10(6). pii: E783. doi: 10.3390/nu10060783.


Docosahexaenoyl serotonin emerges as most potent inhibitor of IL-17 and CCL-20 released by blood mononuclear cells from a series of N-acyl serotonins identified in human intestinal tissue.

Wang Y, Balvers MGJ, Hendriks HFJ, Wilpshaar T, van Heek T, Witkamp RF, Meijerink J.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Sep;1862(9):823-831. doi: 10.1016/j.bbalip.2017.05.008. Epub 2017 May 16.


N-Docosahexaenoyl Dopamine, an Endocannabinoid-like Conjugate of Dopamine and the n-3 Fatty Acid Docosahexaenoic Acid, Attenuates Lipopolysaccharide-Induced Activation of Microglia and Macrophages via COX-2.

Wang Y, Plastina P, Vincken JP, Jansen R, Balvers M, Ten Klooster JP, Gruppen H, Witkamp R, Meijerink J.

ACS Chem Neurosci. 2017 Mar 15;8(3):548-557. doi: 10.1021/acschemneuro.6b00298. Epub 2016 Dec 6.


The Noncaloric Sweetener Rebaudioside A Stimulates Glucagon-Like Peptide 1 Release and Increases Enteroendocrine Cell Numbers in 2-Dimensional Mouse Organoids Derived from Different Locations of the Intestine.

van der Wielen N, Ten Klooster JP, Muckenschnabl S, Pieters R, Hendriks HF, Witkamp RF, Meijerink J.

J Nutr. 2016 Dec;146(12):2429-2435. Epub 2016 Oct 26.


Docosahexaenoyl serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has anti-inflammatory properties by attenuating IL-23-IL-17 signaling in macrophages.

Poland M, Ten Klooster JP, Wang Z, Pieters R, Boekschoten M, Witkamp R, Meijerink J.

Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):2020-2028. doi: 10.1016/j.bbalip.2016.09.012. Epub 2016 Sep 20.


Effect of Endoscopic Gastroplication on the Genome-Wide Transcriptome in the Upper Gastrointestinal Tract.

van der Wielen N, Paulus G, van Avesaat M, Masclee A, Meijerink J, Bouvy N.

Obes Surg. 2017 Mar;27(3):740-748. doi: 10.1007/s11695-016-2356-0.


Nutrient-induced glucagon like peptide-1 release is modulated by serotonin.

Ripken D, van der Wielen N, Wortelboer HM, Meijerink J, Witkamp RF, Hendriks HF.

J Nutr Biochem. 2016 Jun;32:142-50. doi: 10.1016/j.jnutbio.2016.03.006. Epub 2016 Mar 29.


Cross-species comparison of genes related to nutrient sensing mechanisms expressed along the intestine.

van der Wielen N, van Avesaat M, de Wit NJ, Vogels JT, Troost F, Masclee A, Koopmans SJ, van der Meulen J, Boekschoten MV, Müller M, Hendriks HF, Witkamp RF, Meijerink J.

PLoS One. 2014 Sep 12;9(9):e107531. doi: 10.1371/journal.pone.0107531. eCollection 2014.


Steviol glycoside rebaudioside A induces glucagon-like peptide-1 and peptide YY release in a porcine ex vivo intestinal model.

Ripken D, van der Wielen N, Wortelboer HM, Meijerink J, Witkamp RF, Hendriks HF.

J Agric Food Chem. 2014 Aug 20;62(33):8365-70. doi: 10.1021/jf501105w. Epub 2014 Aug 7.


Inhibition of COX-2-mediated eicosanoid production plays a major role in the anti-inflammatory effects of the endocannabinoid N-docosahexaenoylethanolamine (DHEA) in macrophages.

Meijerink J, Poland M, Balvers MG, Plastina P, Lute C, Dwarkasing J, van Norren K, Witkamp RF.

Br J Pharmacol. 2015 Jan;172(1):24-37. doi: 10.1111/bph.12747. Epub 2014 Sep 23.


The endocannabinoid system: an emerging key player in inflammation.

Witkamp R, Meijerink J.

Curr Opin Clin Nutr Metab Care. 2014 Mar;17(2):130-8. doi: 10.1097/MCO.0000000000000027. Review.


Comparative analyses of seeds of wild fruits of Rubus and Sambucus species from Southern Italy: fatty acid composition of the oil, total phenolic content, antioxidant and anti-inflammatory properties of the methanolic extracts.

Fazio A, Plastina P, Meijerink J, Witkamp RF, Gabriele B.

Food Chem. 2013 Oct 15;140(4):817-24. doi: 10.1016/j.foodchem.2012.11.010. Epub 2012 Nov 15.


Measurement of palmitoylethanolamide and other N-acylethanolamines during physiological and pathological conditions.

Balvers MG, Verhoeckx KC, Meijerink J, Wortelboer HM, Witkamp RF.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):23-33. Review.


Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues.

Balvers MG, Verhoeckx KC, Bijlsma S, Rubingh CM, Meijerink J, Wortelboer HM, Witkamp RF.

Metabolomics. 2012 Dec;8(6):1130-1147. Epub 2012 Apr 11.


N-Acyl amines of docosahexaenoic acid and other n-3 polyunsatured fatty acids - from fishy endocannabinoids to potential leads.

Meijerink J, Balvers M, Witkamp R.

Br J Pharmacol. 2013 Jun;169(4):772-83. doi: 10.1111/bph.12030. Review.

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