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Items: 1 to 20 of 26


Synthesis and Antiproliferative Activity of New Cyclodiprenyl Phenols against Select Cancer Cell Lines.

Said B, Montenegro I, Valenzuela M, Olguín Y, Caro N, Werner E, Godoy P, Villena J, Madrid A.

Molecules. 2018 Sep 12;23(9). pii: E2323. doi: 10.3390/molecules23092323.


(-)-Shikimic Acid as a Chiral Building Block for the Synthesis of New Cytotoxic 6-Aza-Analogues of Angucyclinones.

Quiñones N, Hernández S, Espinoza Catalán L, Villena J, Brito I, Cabrera AR, Salas CO, Cuellar MA.

Molecules. 2018 Jun 12;23(6). pii: E1422. doi: 10.3390/molecules23061422.


Structure-Activity Relationship of Dialkoxychalcones to Combat Fish Pathogen Saprolegnia australis.

Montenegro I, Muñoz O, Villena J, Werner E, Mellado M, Ramírez I, Caro N, Flores S, Madrid A.

Molecules. 2018 Jun 7;23(6). pii: E1377. doi: 10.3390/molecules23061377.


Autumn Royal and Ribier Grape Juice Extracts Reduced Viability and Metastatic Potential of Colon Cancer Cells.

Valenzuela M, Bastias L, Montenegro I, Werner E, Madrid A, Godoy P, Párraga M, Villena J.

Evid Based Complement Alternat Med. 2018 Jan 14;2018:2517080. doi: 10.1155/2018/2517080. eCollection 2018.


Antifeedant effect of polygodial and drimenol derivatives against Spodoptera frugiperda and Epilachna paenulata and quantitative structure-activity analysis.

Montenegro IJ, Del Corral S, Diaz Napal GN, Carpinella MC, Mellado M, Madrid AM, Villena J, Palacios SM, Cuellar MA.

Pest Manag Sci. 2018 Jul;74(7):1623-1629. doi: 10.1002/ps.4853. Epub 2018 Mar 2.


Hemi-Synthesis and Anti-Oomycete Activity of Analogues of Isocordoin.

Escobar B, Montenegro I, Villena J, Werner E, Godoy P, Olguín Y, Madrid A.

Molecules. 2017 Jun 10;22(6). pii: E968. doi: 10.3390/molecules22060968.


Synthesis and Evaluation of Novel Oxyalkylated Derivatives of 2',4'-Dihydroxychalcone as Anti-Oomycete Agents against Bronopol Resistant Strains of Saprolegnia sp.

Flores S, Montenegro I, Villena J, Cuellar M, Werner E, Godoy P, Madrid A.

Int J Mol Sci. 2016 Aug 22;17(8). pii: E1366. doi: 10.3390/ijms17081366.


Antiproliferative effect and apoptotic activity of linear geranylphenol derivatives from phloroglucinol and orcinol.

Taborga L, Espinoza L, Moller A, Carrasco H, Cuellar M, Villena J.

Chem Biol Interact. 2016 Mar 5;247:22-9. doi: 10.1016/j.cbi.2016.01.016. Epub 2016 Jan 28.


Cytotoxic and apoptotic effects of leptocarpin, a plant-derived sesquiterpene lactone, on human cancer cell lines.

Bosio C, Tomasoni G, Martínez R, Olea AF, Carrasco H, Villena J.

Chem Biol Interact. 2015 Dec 5;242:415-21. doi: 10.1016/j.cbi.2015.11.006. Epub 2015 Nov 10.


Chemical Characterization and Anti-Oomycete Activity of Laureliopsis philippianna Essential Oils against Saprolegnia parasitica and S. australis.

Madrid A, Godoy P, González S, Zaror L, Moller A, Werner E, Cuellar M, Villena J, Montenegro I.

Molecules. 2015 May 5;20(5):8033-47. doi: 10.3390/molecules20058033.


Psoralea glandulosa as a potential source of anticancer agents for melanoma treatment.

Madrid A, Cardile V, González C, Montenegro I, Villena J, Caggia S, Graziano A, Russo A.

Int J Mol Sci. 2015 Apr 9;16(4):7944-59. doi: 10.3390/ijms16047944.


Oxaliplatin analogues with carboxy derivatives of boldine with enhanced antioxidant activity.

Mellado M, Jara C, Astudillo D, Villena J, Reveco PG, Thomet FA.

Bioinorg Chem Appl. 2015;2015:920143. doi: 10.1155/2015/920143. Epub 2015 Feb 28.


Study on the cytotoxic activity of drimane sesquiterpenes and nordrimane compounds against cancer cell lines.

Montenegro I, Tomasoni G, Bosio C, Quiñones N, Madrid A, Carrasco H, Olea A, Martinez R, Cuellar M, Villena J.

Molecules. 2014 Nov 18;19(11):18993-9006. doi: 10.3390/molecules191118993.


Diterpenylhydroquinones from natural ent-labdanes induce apoptosis through decreased mitochondrial membrane potential.

Villena J, Madrid A, Montenegro I, Werner E, Cuellar M, Espinoza L.

Molecules. 2013 May 10;18(5):5348-59. doi: 10.3390/molecules18055348.


Comparative study on the larvicidal activity of drimane sesquiterpenes and nordrimane compounds against Drosophila melanogaster til-til.

Montenegro I, Pino L, Werner E, Madrid A, Espinoza L, Moreno L, Villena J, Cuellar M.

Molecules. 2013 Apr 10;18(4):4192-208. doi: 10.3390/molecules18044192.


Daidzein-estrogen interaction in the rat uterus and its effect on human breast cancer cell growth.

Gaete L, Tchernitchin AN, Bustamante R, Villena J, Lemus I, Gidekel M, Cabrera G, Astorga P.

J Med Food. 2012 Dec;15(12):1081-90. doi: 10.1089/jmf.2011.0322. Epub 2012 Dec 10.


Antifungal study of the resinous exudate and of meroterpenoids isolated from Psoralea glandulosa (Fabaceae).

Madrid A, Espinoza L, González C, Mellado M, Villena J, Santander R, Silva V, Montenegro I.

J Ethnopharmacol. 2012 Dec 18;144(3):809-11. doi: 10.1016/j.jep.2012.10.027. Epub 2012 Oct 23.


Genistein selectively inhibits estrogen-induced cell proliferation and other responses to hormone stimulation in the prepubertal rat uterus.

Gaete L, Tchernitchin AN, Bustamante R, Villena J, Lemus I, Gidekel M, Cabrera G, Carrillo O.

J Med Food. 2011 Dec;14(12):1597-603. doi: 10.1089/jmf.2010.0349. Epub 2011 May 25.


In vitro cytotoxic evaluation of a novel phosphinyl derivative of boldine.

Thomet FA, Piñol P, Villena J, Reveco PG.

Molecules. 2011 Mar 7;16(3):2253-8. doi: 10.3390/molecules16032253.


Cytotoxic thiocarbamate derivatives of boldine.

Thomet FA, Pinyol P, Villena J, Espinoza LJ, Reveco PG.

Nat Prod Commun. 2010 Oct;5(10):1587-90.


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