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Items: 1 to 20 of 41

1.

An alternative membrane topology permits lipid droplet localization of peroxisomal fatty acyl-CoA reductase 1.

Exner T, Romero-Brey I, Yifrach E, Rivera-Monroy J, Schrul B, Zouboulis CC, Stremmel W, Honsho M, Bartenschlager R, Zalckvar E, Poppelreuther M, Füllekrug J.

J Cell Sci. 2019 Mar 18;132(6). pii: jcs223016. doi: 10.1242/jcs.223016.

PMID:
30745342
2.

Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways.

Young PA, Senkal CE, Suchanek AL, Grevengoed TJ, Lin DD, Zhao L, Crunk AE, Klett EL, Füllekrug J, Obeid LM, Coleman RA.

J Biol Chem. 2018 Oct 26;293(43):16724-16740. doi: 10.1074/jbc.RA118.004049. Epub 2018 Sep 6.

PMID:
30190326
3.

The metabolic capacity of lipid droplet localized acyl-CoA synthetase 3 is not sufficient to support local triglyceride synthesis independent of the endoplasmic reticulum in A431 cells.

Poppelreuther M, Sander S, Minden F, Dietz MS, Exner T, Du C, Zhang I, Ehehalt F, Knüppel L, Domschke S, Badenhop A, Staudacher S, Ehehalt R, Stremmel W, Thiele C, Heilemann M, Füllekrug J.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jun;1863(6):614-624. doi: 10.1016/j.bbalip.2018.03.003. Epub 2018 Mar 9.

PMID:
29526665
4.

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.

Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H, Trümbach D, Mao G, Qu F, Bayir H, Füllekrug J, Scheel CH, Wurst W, Schick JA, Kagan VE, Angeli JP, Conrad M.

Nat Chem Biol. 2017 Jan;13(1):91-98. doi: 10.1038/nchembio.2239. Epub 2016 Nov 14.

5.

Generation and functional characterization of epithelial cells with stable expression of SLC26A9 Cl- channels.

Salomon JJ, Spahn S, Wang X, Füllekrug J, Bertrand CA, Mall MA.

Am J Physiol Lung Cell Mol Physiol. 2016 Apr 1;310(7):L593-602. doi: 10.1152/ajplung.00321.2015. Epub 2016 Jan 22.

6.

Measurement of Long-Chain Fatty Acyl-CoA Synthetase Activity.

Füllekrug J, Poppelreuther M.

Methods Mol Biol. 2016;1376:43-53. doi: 10.1007/978-1-4939-3170-5_5.

PMID:
26552674
7.

Protein mediated fatty acid uptake: synergy between CD36/FAT-facilitated transport and acyl-CoA synthetase-driven metabolism.

Schneider H, Staudacher S, Poppelreuther M, Stremmel W, Ehehalt R, Füllekrug J.

Arch Biochem Biophys. 2014 Mar 15;546:8-18. doi: 10.1016/j.abb.2014.01.025. Epub 2014 Feb 4.

PMID:
24503477
8.

Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol.

Küch EM, Vellaramkalayil R, Zhang I, Lehnen D, Brügger B, Sreemmel W, Ehehalt R, Poppelreuther M, Füllekrug J.

Biochim Biophys Acta. 2014 Feb;1841(2):227-39.

PMID:
24201376
9.

Outlook: membrane junctions enable the metabolic trapping of fatty acids by intracellular acyl-CoA synthetases.

Füllekrug J, Ehehalt R, Poppelreuther M.

Front Physiol. 2012 Oct 10;3:401. doi: 10.3389/fphys.2012.00401. eCollection 2012.

10.
11.

The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake.

Poppelreuther M, Rudolph B, Du C, Großmann R, Becker M, Thiele C, Ehehalt R, Füllekrug J.

J Lipid Res. 2012 May;53(5):888-900. doi: 10.1194/jlr.M024562. Epub 2012 Feb 22.

12.

Enhanced fatty acid oxidation and FATP4 protein expression after endurance exercise training in human skeletal muscle.

Jeppesen J, Jordy AB, Sjøberg KA, Füllekrug J, Stahl A, Nybo L, Kiens B.

PLoS One. 2012;7(1):e29391. doi: 10.1371/journal.pone.0029391. Epub 2012 Jan 3.

13.

Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells.

Krammer J, Digel M, Ehehalt F, Stremmel W, Füllekrug J, Ehehalt R.

Int J Med Sci. 2011;8(7):599-614. Epub 2011 Oct 7.

14.

Adipocyte-specific inactivation of Acyl-CoA synthetase fatty acid transport protein 4 (Fatp4) in mice causes adipose hypertrophy and alterations in metabolism of complex lipids under high fat diet.

Lenz LS, Marx J, Chamulitrat W, Kaiser I, Gröne HJ, Liebisch G, Schmitz G, Elsing C, Straub BK, Füllekrug J, Stremmel W, Herrmann T.

J Biol Chem. 2011 Oct 14;286(41):35578-87. doi: 10.1074/jbc.M111.226530. Epub 2011 Jul 31.

15.

FATP4 contributes as an enzyme to the basal and insulin-mediated fatty acid uptake of C₂C₁₂ muscle cells.

Digel M, Staffer S, Ehehalt F, Stremmel W, Ehehalt R, Füllekrug J.

Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E785-96. doi: 10.1152/ajpendo.00079.2011. Epub 2011 Jul 12.

16.

Silybin and dehydrosilybin decrease glucose uptake by inhibiting GLUT proteins.

Zhan T, Digel M, Küch EM, Stremmel W, Füllekrug J.

J Cell Biochem. 2011 Mar;112(3):849-59. doi: 10.1002/jcb.22984.

PMID:
21328458
17.

Lipid based therapy for ulcerative colitis-modulation of intestinal mucus membrane phospholipids as a tool to influence inflammation.

Schneider H, Braun A, Füllekrug J, Stremmel W, Ehehalt R.

Int J Mol Sci. 2010 Oct 25;11(10):4149-64. doi: 10.3390/ijms11104149. Review.

18.

Knockdown of caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity.

Herzog M, Storch CH, Gut P, Kotlyar D, Füllekrug J, Ehehalt R, Haefeli WE, Weiss J.

Naunyn Schmiedebergs Arch Pharmacol. 2011 Jan;383(1):1-11. doi: 10.1007/s00210-010-0568-8. Epub 2010 Oct 10.

PMID:
20936466
19.

Phosphatidylcholine as a constituent in the colonic mucosal barrier--physiological and clinical relevance.

Ehehalt R, Braun A, Karner M, Füllekrug J, Stremmel W.

Biochim Biophys Acta. 2010 Sep;1801(9):983-93. doi: 10.1016/j.bbalip.2010.05.014. Epub 2010 Jun 4. Review.

PMID:
20595010
20.

Genetic analysis of BIRC4/XIAP as a putative modifier gene of Wilson disease.

Weiss KH, Runz H, Noe B, Gotthardt DN, Merle U, Ferenci P, Stremmel W, Füllekrug J.

J Inherit Metab Dis. 2010 Dec;33 Suppl 3:S233-40. doi: 10.1007/s10545-010-9123-5. Epub 2010 Jun 2.

PMID:
20517649

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