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Author Correction: Structure of full-length wild-type human phenylalanine hydroxylase by small angle X-ray scattering reveals substrate-induced conformational stability.

Tomé CS, Lopes RR, Sousa PMF, Amaro MP, Leandro J, Mertens HDT, Leandro P, Vicente JB.

Sci Rep. 2019 Nov 20;9(1):17513. doi: 10.1038/s41598-019-54425-2.


Targeting Glutathione and Cystathionine β-Synthase in Ovarian Cancer Treatment by Selenium-Chrysin Polyurea Dendrimer Nanoformulation.

Santos I, Ramos C, Mendes C, Sequeira CO, Tomé CS, Fernandes DGH, Mota P, Pires RF, Urso D, Hipólito A, Antunes AMM, Vicente JB, Pereira SA, Bonifácio VDB, Nunes SC, Serpa J.

Nutrients. 2019 Oct 19;11(10). pii: E2523. doi: 10.3390/nu11102523.


Structure of full-length wild-type human phenylalanine hydroxylase by small angle X-ray scattering reveals substrate-induced conformational stability.

Tomé CS, Lopes RR, Sousa PMF, Amaro MP, Leandro J, Mertens HDT, Leandro P, Vicente JB.

Sci Rep. 2019 Sep 20;9(1):13615. doi: 10.1038/s41598-019-49944-x. Erratum in: Sci Rep. 2019 Nov 20;9(1):17513.


N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells.

Zuhra K, Tomé CS, Masi L, Giardina G, Paulini G, Malagrinò F, Forte E, Vicente JB, Giuffrè A.

Cells. 2019 Aug 4;8(8). pii: E828. doi: 10.3390/cells8080828.


Hydrogen Sulfide Oxidation: Adaptive Changes in Mitochondria of SW480 Colorectal Cancer Cells upon Exposure to Hypoxia.

Malagrinò F, Zuhra K, Mascolo L, Mastronicola D, Vicente JB, Forte E, Giuffrè A.

Oxid Med Cell Longev. 2019 Jan 29;2019:8102936. doi: 10.1155/2019/8102936. eCollection 2019.


Screening Pyridine Derivatives against Human Hydrogen Sulfide-synthesizing Enzymes by Orthogonal Methods.

Zuhra K, Sousa PMF, Paulini G, Lemos AR, Kalme Z, Bisenieks I, Bisenieks E, Vigante B, Duburs G, Bandeiras TM, Saso L, Giuffrè A, Vicente JB.

Sci Rep. 2019 Jan 24;9(1):684. doi: 10.1038/s41598-018-36994-w.


Hydrogen Sulfide Biochemistry and Interplay with Other Gaseous Mediators in Mammalian Physiology.

Giuffrè A, Vicente JB.

Oxid Med Cell Longev. 2018 Jun 27;2018:6290931. doi: 10.1155/2018/6290931. eCollection 2018. Review.


Cytochrome bd and Gaseous Ligands in Bacterial Physiology.

Forte E, Borisov VB, Vicente JB, Giuffrè A.

Adv Microb Physiol. 2017;71:171-234. doi: 10.1016/bs.ampbs.2017.05.002. Epub 2017 Jul 10. Review.


A Clinically Relevant Variant of the Human Hydrogen Sulfide-Synthesizing Enzyme Cystathionine β-Synthase: Increased CO Reactivity as a Novel Molecular Mechanism of Pathogenicity?

Vicente JB, Colaço HG, Malagrinò F, Santo PE, Gutierres A, Bandeiras TM, Leandro P, Brito JA, Giuffrè A.

Oxid Med Cell Longev. 2017;2017:8940321. doi: 10.1155/2017/8940321. Epub 2017 Mar 22.


Sweet and sour: an update on classic galactosemia.

Coelho AI, Rubio-Gozalbo ME, Vicente JB, Rivera I.

J Inherit Metab Dis. 2017 May;40(3):325-342. doi: 10.1007/s10545-017-0029-3. Epub 2017 Mar 9. Review.


Structure of Escherichia coli Flavodiiron Nitric Oxide Reductase.

Romão CV, Vicente JB, Borges PT, Victor BL, Lamosa P, Silva E, Pereira L, Bandeiras TM, Soares CM, Carrondo MA, Turner D, Teixeira M, Frazão C.

J Mol Biol. 2016 Nov 20;428(23):4686-4707. doi: 10.1016/j.jmb.2016.10.008. Epub 2016 Oct 7.


Bioenergetic relevance of hydrogen sulfide and the interplay between gasotransmitters at human cystathionine β-synthase.

Vicente JB, Malagrinò F, Arese M, Forte E, Sarti P, Giuffrè A.

Biochim Biophys Acta. 2016 Aug;1857(8):1127-1138. doi: 10.1016/j.bbabio.2016.03.030. Epub 2016 Mar 31. Review.


The Terminal Oxidase Cytochrome bd Promotes Sulfide-resistant Bacterial Respiration and Growth.

Forte E, Borisov VB, Falabella M, Colaço HG, Tinajero-Trejo M, Poole RK, Vicente JB, Sarti P, Giuffrè A.

Sci Rep. 2016 Mar 31;6:23788. doi: 10.1038/srep23788.


The dual function of flavodiiron proteins: oxygen and/or nitric oxide reductases.

Romão CV, Vicente JB, Borges PT, Frazão C, Teixeira M.

J Biol Inorg Chem. 2016 Mar;21(1):39-52. doi: 10.1007/s00775-015-1329-4. Epub 2016 Jan 14. Review.


S-Adenosyl-l-methionine Modulates CO and NO• Binding to the Human H2S-generating Enzyme Cystathionine β-Synthase.

Vicente JB, Colaço HG, Sarti P, Leandro P, Giuffrè A.

J Biol Chem. 2016 Jan 8;291(2):572-81. doi: 10.1074/jbc.M115.681221. Epub 2015 Nov 18.


Small aminothiol compounds improve the function of Arg to Cys variant proteins: effect on the human cystathionine β-synthase p.R336C.

Mendes MI, Smith DE, Vicente JB, Tavares De Almeida I, Ben-Omran T, Salomons GS, Rivera IA, Leandro P, Blom HJ.

Hum Mol Genet. 2015 Dec 20;24(25):7339-48. doi: 10.1093/hmg/ddv431. Epub 2015 Oct 12.


Arginine Functionally Improves Clinically Relevant Human Galactose-1-Phosphate Uridylyltransferase (GALT) Variants Expressed in a Prokaryotic Model.

Coelho AI, Trabuco M, Silva MJ, de Almeida IT, Leandro P, Rivera I, Vicente JB.

JIMD Rep. 2015;23:1-6. doi: 10.1007/8904_2015_420. Epub 2015 Mar 27.


Functional and structural impact of the most prevalent missense mutations in classic galactosemia.

Coelho AI, Trabuco M, Ramos R, Silva MJ, Tavares de Almeida I, Leandro P, Rivera I, Vicente JB.

Mol Genet Genomic Med. 2014 Nov;2(6):484-96. doi: 10.1002/mgg3.94. Epub 2014 Jun 23.


Flavodiiron oxygen reductase from Entamoeba histolytica: modulation of substrate preference by tyrosine 271 and lysine 53.

Gonçalves VL, Vicente JB, Pinto L, Romão CV, Frazão C, Sarti P, Giuffrè A, Teixeira M.

J Biol Chem. 2014 Oct 10;289(41):28260-70. doi: 10.1074/jbc.M114.579086. Epub 2014 Aug 23.


Functional correction by antisense therapy of a splicing mutation in the GALT gene.

Coelho AI, Lourenço S, Trabuco M, Silva MJ, Oliveira A, Gaspar A, Diogo L, Tavares de Almeida I, Vicente JB, Rivera I.

Eur J Hum Genet. 2015 Apr;23(4):500-6. doi: 10.1038/ejhg.2014.149. Epub 2014 Jul 23.

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