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Items: 17


Protective Role of Shiitake Mushroom-Derived Exosome-Like Nanoparticles in D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.

Liu B, Lu Y, Chen X, Muthuraj PG, Li X, Pattabiraman M, Zempleni J, Kachman SD, Natarajan SK, Yu J.

Nutrients. 2020 Feb 13;12(2). pii: E477. doi: 10.3390/nu12020477.


Exosome-like Nanoparticles from Ginger Rhizomes Inhibited NLRP3 Inflammasome Activation.

Chen X, Zhou Y, Yu J.

Mol Pharm. 2019 Jun 3;16(6):2690-2699. doi: 10.1021/acs.molpharmaceut.9b00246. Epub 2019 Apr 30.


ARMMs as a versatile platform for intracellular delivery of macromolecules.

Wang Q, Yu J, Kadungure T, Beyene J, Zhang H, Lu Q.

Nat Commun. 2018 Mar 6;9(1):960. doi: 10.1038/s41467-018-03390-x.


Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation.

Covarrubias AJ, Aksoylar HI, Yu J, Snyder NW, Worth AJ, Iyer SS, Wang J, Ben-Sahra I, Byles V, Polynne-Stapornkul T, Espinosa EC, Lamming D, Manning BD, Zhang Y, Blair IA, Horng T.

Elife. 2016 Feb 19;5. pii: e11612. doi: 10.7554/eLife.11612.


Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy.

Yu J, Nagasu H, Murakami T, Hoang H, Broderick L, Hoffman HM, Horng T.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15514-9. doi: 10.1073/pnas.1414859111. Epub 2014 Oct 13.


Metabolic characterization of a Sirt5 deficient mouse model.

Yu J, Sadhukhan S, Noriega LG, Moullan N, He B, Weiss RS, Lin H, Schoonjans K, Auwerx J.

Sci Rep. 2013 Sep 30;3:2806. doi: 10.1038/srep02806.


Critical role for calcium mobilization in activation of the NLRP3 inflammasome.

Murakami T, Ockinger J, Yu J, Byles V, McColl A, Hofer AM, Horng T.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11282-7. doi: 10.1073/pnas.1117765109. Epub 2012 Jun 25.


CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability.

Noriega LG, Feige JN, Canto C, Yamamoto H, Yu J, Herman MA, Mataki C, Kahn BB, Auwerx J.

EMBO Rep. 2011 Sep 30;12(10):1069-76. doi: 10.1038/embor.2011.151.


Protein deacetylation by SIRT1: an emerging key post-translational modification in metabolic regulation.

Yu J, Auwerx J.

Pharmacol Res. 2010 Jul;62(1):35-41. doi: 10.1016/j.phrs.2009.12.006. Epub 2009 Dec 21. Review.


The role of sirtuins in the control of metabolic homeostasis.

Yu J, Auwerx J.

Ann N Y Acad Sci. 2009 Sep;1173 Suppl 1:E10-9. doi: 10.1111/j.1749-6632.2009.04952.x. Review.


The N-CoR complex enables chromatin remodeler SNF2H to enhance repression by thyroid hormone receptor.

Alenghat T, Yu J, Lazar MA.

EMBO J. 2006 Sep 6;25(17):3966-74. Epub 2006 Aug 17.


Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressor.

Macfarlan T, Kutney S, Altman B, Montross R, Yu J, Chakravarti D.

J Biol Chem. 2005 Feb 25;280(8):7346-58. Epub 2004 Nov 23.


A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation.

Yu J, Li Y, Ishizuka T, Guenther MG, Lazar MA.

EMBO J. 2003 Jul 1;22(13):3403-10.


Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex.

Guenther MG, Yu J, Kao GD, Yen TJ, Lazar MA.

Genes Dev. 2002 Dec 15;16(24):3130-5.

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