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Items: 1 to 20 of 74

1.

Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.

Wang Y, Lou Y, Wang J, Li D, Chen H, Zheng T, Xia C, Song X, Dong T, Li J, Li J, Liu H.

Eur J Med Chem. 2019 Jul 10;180:398-416. doi: 10.1016/j.ejmech.2019.07.032. [Epub ahead of print]

PMID:
31325786
2.

HS-β-cyclodextrin-functionalized Ag@Fe3O4@Ag nanoparticles as a surface-enhanced Raman spectroscopy substrate for the sensitive detection of butyl benzyl phthalate.

Zhou Y, Li J, Zhang L, Ge Z, Wang X, Hu X, Xu T, Li P, Xu W.

Anal Bioanal Chem. 2019 Sep;411(22):5691-5701. doi: 10.1007/s00216-019-01947-3. Epub 2019 Jul 5.

PMID:
31278553
3.

Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans.

Wu L, Xia M, Duan Y, Zhang L, Jiang H, Hu X, Yan H, Zhang Y, Gu Y, Shi H, Li J, Gao X, Li J.

Cell Death Dis. 2019 Jun 13;10(6):468. doi: 10.1038/s41419-019-1706-y.

4.

Bimetallic plasmonic Au@Ag nanocuboids for rapid and sensitive detection of phthalate plasticizers with label-free surface-enhanced Raman spectroscopy.

Hu X, Wang X, Ge Z, Zhang L, Zhou Y, Li J, Bu L, Wu H, Li P, Xu W.

Analyst. 2019 Jun 21;144(12):3861-3869. doi: 10.1039/c9an00251k. Epub 2019 May 17.

PMID:
31099357
5.

Correction to Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes.

Li S, Qin C, Cui S, Xu H, Wu F, Wang J, Su M, Fang X, Li D, Jiao Q, Zhang M, Xia C, Zhu L, Wang R, Li J, Jiang H, Zhao Z, Li J, Li H.

J Med Chem. 2019 May 9;62(9):4779. doi: 10.1021/acs.jmedchem.9b00559. Epub 2019 Apr 17. No abstract available.

PMID:
30995042
6.

Synthesis and biological evaluation of tryptophan-derived rhodanine derivatives as PTP1B inhibitors and anti-bacterial agents.

Liu H, Sun D, Du H, Zheng C, Li J, Piao H, Li J, Sun L.

Eur J Med Chem. 2019 Jun 15;172:163-173. doi: 10.1016/j.ejmech.2019.03.059. Epub 2019 Mar 30.

PMID:
30978561
7.

Transition-Metal-Free Oxidation of Benzylic C-H Bonds of Six-Membered N-Heteroaromatic Compounds.

Gao X, Han S, Zheng M, Liang A, Li J, Zou D, Wu Y, Wu Y.

J Org Chem. 2019 Apr 5;84(7):4040-4049. doi: 10.1021/acs.joc.9b00035. Epub 2019 Mar 19.

PMID:
30854850
8.

Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene.

Han Y, Hu Z, Cui A, Liu Z, Ma F, Xue Y, Liu Y, Zhang F, Zhao Z, Yu Y, Gao J, Wei C, Li J, Fang J, Li J, Fan JG, Song BL, Li Y.

Nat Commun. 2019 Feb 7;10(1):623. doi: 10.1038/s41467-019-08585-4.

9.

Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes.

Li S, Qin C, Cui S, Xu H, Wu F, Wang J, Su M, Fang X, Li D, Jiao Q, Zhang M, Xia C, Zhu L, Wang R, Li J, Jiang H, Zhao Z, Li J, Li H.

J Med Chem. 2019 Mar 14;62(5):2348-2361. doi: 10.1021/acs.jmedchem.8b01491. Epub 2019 Feb 13. Erratum in: J Med Chem. 2019 May 9;62(9):4779.

PMID:
30694668
10.

Oropharyngeal Muscle Exercise Therapy Improves Signs and Symptoms of Post-stroke Moderate Obstructive Sleep Apnea Syndrome.

Ye D, Chen C, Song D, Shen M, Liu H, Zhang S, Zhang H, Li J, Yu W, Wang Q.

Front Neurol. 2018 Oct 29;9:912. doi: 10.3389/fneur.2018.00912. eCollection 2018.

11.

Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles.

Guo B, Guo S, Huang J, Li J, Li J, Chen Q, Zhou X, Xie X, Yang Y.

Bioorg Med Chem. 2018 Dec 1;26(22):5780-5791. doi: 10.1016/j.bmc.2018.10.019. Epub 2018 Oct 22.

PMID:
30392954
12.

Pd-Catalyzed Alkylation of (Iso)quinolines and Arenes: 2-Acylpyridine Compounds as Alkylation Reagents.

Wu Q, Han S, Ren X, Lu H, Li J, Zou D, Wu Y, Wu Y.

Org Lett. 2018 Oct 19;20(20):6345-6348. doi: 10.1021/acs.orglett.8b02498. Epub 2018 Oct 4.

PMID:
30284838
13.

Effects of sodium bicarbonate on cell growth, lipid accumulation, and morphology of Chlorella vulgaris.

Li J, Li C, Lan CQ, Liao D.

Microb Cell Fact. 2018 Jul 9;17(1):111. doi: 10.1186/s12934-018-0953-4.

14.

Liquid-liquid interfacial self-assembled Au NP arrays for the rapid and sensitive detection of butyl benzyl phthalate (BBP) by surface-enhanced Raman spectroscopy.

Liu J, Li J, Li F, Zhou Y, Hu X, Xu T, Xu W.

Anal Bioanal Chem. 2018 Aug;410(21):5277-5285. doi: 10.1007/s00216-018-1184-6. Epub 2018 Jun 25.

PMID:
29943263
15.

Nickel-Catalyzed Direct C-H Trifluoromethylation of Free Anilines with Togni's Reagent.

Gao X, Geng Y, Han S, Liang A, Li J, Zou D, Wu Y, Wu Y.

Org Lett. 2018 Jul 6;20(13):3732-3735. doi: 10.1021/acs.orglett.8b01216. Epub 2018 Jun 19.

PMID:
29920105
16.

Achyranthis bidentatae radix enhanced articular distribution and anti-inflammatory effect of berberine in Sanmiao Wan using an acute gouty arthritis rat model.

Wu J, Li J, Li W, Sun B, Xie J, Cheng W, Zhang Q.

J Ethnopharmacol. 2018 Jul 15;221:100-108. doi: 10.1016/j.jep.2018.04.025. Epub 2018 Apr 18.

PMID:
29679725
17.

Structural equation modeling of PAHs in ambient air, dust fall, soil, and cabbage in vegetable bases of Northern China.

Zhang Y, Hou D, Xiong G, Duan Y, Cai C, Wang X, Li J, Tao S, Liu W.

Environ Pollut. 2018 Aug;239:13-20. doi: 10.1016/j.envpol.2018.03.084. Epub 2018 Apr 5.

PMID:
29627685
18.

Clinical and Physiological Characterization of Elevated Plasma Glucagon-Like Peptide-1 Levels (Hyperglipemia) in a Dipeptidyl Peptidase IV Mutation Carrier.

Zhao D, Zhao S, Wang X, Su M, Liu W, Ma Q, Hong J, Gu W, Li J, Liu R, Ning G, Wang J, Zhang Y.

Front Endocrinol (Lausanne). 2018 Mar 5;9:62. doi: 10.3389/fendo.2018.00062. eCollection 2018.

20.

AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue.

Wu L, Zhang L, Li B, Jiang H, Duan Y, Xie Z, Shuai L, Li J, Li J.

Front Physiol. 2018 Feb 21;9:122. doi: 10.3389/fphys.2018.00122. eCollection 2018.

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