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Items: 9


Gram-scale total synthesis of teixobactin promoting binding mode study and discovery of more potent antibiotics.

Zong Y, Fang F, Meyer KJ, Wang L, Ni Z, Gao H, Lewis K, Zhang J, Rao Y.

Nat Commun. 2019 Jul 22;10(1):3268. doi: 10.1038/s41467-019-11211-y.


A Cinchona Alkaloid Antibiotic That Appears To Target ATP Synthase in Streptococcus pneumoniae.

Wang X, Zeng Y, Sheng L, Larson P, Liu X, Zou X, Wang S, Guo K, Ma C, Zhang G, Cui H, Ferguson DM, Li Y, Zhang J, Aldrich CC.

J Med Chem. 2019 Mar 14;62(5):2305-2332. doi: 10.1021/acs.jmedchem.8b01353. Epub 2019 Mar 1.


Characterization of Streptococcus pluranimalium from a cattle with mastitis by whole genome sequencing and functional validation.

Pan Y, An H, Fu T, Zhao S, Zhang C, Xiao G, Zhang J, Zhao X, Hu G.

BMC Microbiol. 2018 Nov 12;18(1):182. doi: 10.1186/s12866-018-1327-0.


An Interleukin-25-Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin Inflammation.

Xu M, Lu H, Lee YH, Wu Y, Liu K, Shi Y, An H, Zhang J, Wang X, Lai Y, Dong C.

Immunity. 2018 Apr 17;48(4):787-798.e4. doi: 10.1016/j.immuni.2018.03.019. Epub 2018 Apr 10.


Discovery of a Teraryl Oxazolidinone Compound (S)-N-((3-(3-Fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Phosphate as a Novel Antimicrobial Agent with Enhanced Safety Profile and Efficacies.

Yang T, Chen G, Sang Z, Liu Y, Yang X, Chang Y, Long H, Ang W, Tang J, Wang Z, Li G, Yang S, Zhang J, Wei Y, Luo Y.

J Med Chem. 2015 Aug 27;58(16):6389-409. doi: 10.1021/acs.jmedchem.5b00152. Epub 2015 Aug 17.


Cyclic Hexapeptides from the Deep South China Sea-Derived Streptomyces scopuliridis SCSIO ZJ46 Active Against Pathogenic Gram-Positive Bacteria.

Song Y, Li Q, Liu X, Chen Y, Zhang Y, Sun A, Zhang W, Zhang J, Ju J.

J Nat Prod. 2014 Aug 22;77(8):1937-41. doi: 10.1021/np500399v.


The two-component system Ihk/Irr contributes to the virulence of Streptococcus suis serotype 2 strain 05ZYH33 through alteration of the bacterial cell metabolism.

Han H, Liu C, Wang Q, Xuan C, Zheng B, Tang J, Yan J, Zhang J, Li M, Cheng H, Lu G, Gao GF.

Microbiology. 2012 Jul;158(Pt 7):1852-1866. doi: 10.1099/mic.0.057448-0. Epub 2012 Apr 13.


Insight into the interaction of metal ions with TroA from Streptococcus suis.

Zheng B, Zhang Q, Gao J, Han H, Li M, Zhang J, Qi J, Yan J, Gao GF.

PLoS One. 2011;6(5):e19510. doi: 10.1371/journal.pone.0019510. Epub 2011 May 18.


Crystal structures of Streptococcus suis mannonate dehydratase (ManD) and its complex with substrate: genetic and biochemical evidence for a catalytic mechanism.

Zhang Q, Gao F, Peng H, Cheng H, Liu Y, Tang J, Thompson J, Wei G, Zhang J, Du Y, Yan J, Gao GF.

J Bacteriol. 2009 Sep;191(18):5832-7. doi: 10.1128/JB.00599-09. Epub 2009 Jul 17.

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