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Items: 16


Isorhapontigenin (ISO) inhibits stem cell-like properties and invasion of bladder cancer cell by attenuating CD44 expression.

Luo Y, Tian Z, Hua X, Huang M, Xu J, Li J, Huang H, Cohen M, Huang C.

Cell Mol Life Sci. 2019 Jun 20. doi: 10.1007/s00018-019-03185-3. [Epub ahead of print]


Transcriptionally elevation of miR-494 by new ChlA-F compound via a HuR/JunB axis inhibits human bladder cancer cell invasion.

Tian Z, Luo Y, Zhu J, Hua X, Xu J, Huang C, Jin H, Huang H, Huang C.

Biochim Biophys Acta Gene Regul Mech. 2019 Jun 2. pii: S1874-9399(19)30018-5. doi: 10.1016/j.bbagrm.2019.05.007. [Epub ahead of print]


ATG7 Promotes Bladder Cancer Invasion via Autophagy-Mediated Increased ARHGDIB mRNA Stability.

Zhu J, Tian Z, Li Y, Hua X, Zhang D, Li J, Jin H, Xu J, Chen W, Niu B, Wu XR, Comincini S, Huang H, Huang C.

Adv Sci (Weinh). 2019 Feb 22;6(8):1801927. doi: 10.1002/advs.201801927. eCollection 2019 Apr 17.


miR-3687 Overexpression Promotes Bladder Cancer Cell Growth by Inhibiting the Negative Effect of FOXP1 on Cyclin E2 Transcription.

Xie Q, Chen C, Li H, Xu J, Wu L, Yu Y, Ren S, Li H, Hua X, Yan H, Rao D, Zhang H, Jin H, Huang H, Huang C.

Mol Ther. 2019 May 8;27(5):1028-1038. doi: 10.1016/j.ymthe.2019.03.006. Epub 2019 Mar 15.


A Feedback Loop Formed by ATG7/Autophagy, FOXO3a/miR-145 and PD-L1 Regulates Stem-Like Properties and Invasion in Human Bladder Cancer.

Zhu J, Li Y, Luo Y, Xu J, Liufu H, Tian Z, Huang C, Li J, Huang C.

Cancers (Basel). 2019 Mar 12;11(3). pii: E349. doi: 10.3390/cancers11030349.


Autophagy-mediated Mir6981 degradation exhibits CDKN1B promotion of PHLPP1 protein translation.

Peng M, Wang J, Tian Z, Zhang D, Jin H, Liu C, Xu J, Li J, Hua X, Xu J, Huang C, Huang C.

Autophagy. 2019 Mar 1:1-16. doi: 10.1080/15548627.2019.1586254. [Epub ahead of print]


CD44s is a crucial ATG7 downstream regulator for stem-like property, invasion, and lung metastasis of human bladder cancer (BC) cells.

Zhu J, Huang G, Hua X, Li Y, Yan H, Che X, Tian Z, Liufu H, Huang C, Li J, Xu J, Dai W, Huang H, Huang C.

Oncogene. 2019 Apr;38(17):3301-3315. doi: 10.1038/s41388-018-0664-7. Epub 2019 Jan 11.


Treatment of hyperphosphatemia based on specific interactions between phosphorus and Zr(iv) active centers of nano-MOFs.

Zhang W, Xu J, Li P, Gao X, Zhang W, Wang H, Tang B.

Chem Sci. 2018 Jul 23;9(38):7483-7487. doi: 10.1039/c8sc02638f. eCollection 2018 Oct 14.


ISO, via Upregulating MiR-137 Transcription, Inhibits GSK3β-HSP70-MMP-2 Axis, Resulting in Attenuating Urothelial Cancer Invasion.

Guo X, Huang H, Jin H, Xu J, Risal S, Li J, Li X, Yan H, Zeng X, Xue L, Chen C, Huang C.

Mol Ther Nucleic Acids. 2018 Sep 7;12:337-349. doi: 10.1016/j.omtn.2018.05.017. Epub 2018 Jul 4.


New compound ChlA-F induces autophagy-dependent anti-cancer effect via upregulating Sestrin-2 in human bladder cancer.

Hua X, Xu J, Deng X, Xu J, Li J, Zhu DQ, Zhu J, Jin H, Tian Z, Huang H, Zhao QS, Huang C.

Cancer Lett. 2018 Nov 1;436:38-51. doi: 10.1016/j.canlet.2018.08.013. Epub 2018 Aug 16.


Decreased c-Myc mRNA Stability via the MicroRNA 141-3p/AUF1 Axis Is Crucial for p63α Inhibition of Cyclin D1 Gene Transcription and Bladder Cancer Cell Tumorigenicity.

Li X, Tian Z, Jin H, Xu J, Hua X, Yan H, Liufu H, Wang J, Li J, Zhu J, Huang H, Huang C.

Mol Cell Biol. 2018 Oct 15;38(21). pii: e00273-18. doi: 10.1128/MCB.00273-18. Print 2018 Nov 1.


XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin-mediated Rho-GDIβ mRNA stability.

Yu Y, Jin H, Xu J, Gu J, Li X, Xie Q, Huang H, Li J, Tian Z, Jiang G, Chen C, He F, Wu XR, Huang C.

Int J Cancer. 2018 May 15;142(10):2040-2055. doi: 10.1002/ijc.31223. Epub 2017 Dec 28.


p63α protein up-regulates heat shock protein 70 expression via E2F1 transcription factor 1, promoting Wasf3/Wave3/MMP9 signaling and bladder cancer invasion.

Jin H, Xie Q, Guo X, Xu J, Wang A, Li J, Zhu J, Wu XR, Huang H, Huang C.

J Biol Chem. 2017 Sep 22;292(38):15952-15963. doi: 10.1074/jbc.M117.792010. Epub 2017 Aug 9.


NF-κB p65 Overexpression Promotes Bladder Cancer Cell Migration via FBW7-Mediated Degradation of RhoGDIα Protein.

Zhu J, Li Y, Chen C, Ma J, Sun W, Tian Z, Li J, Xu J, Liu CS, Zhang D, Huang C, Huang H.

Neoplasia. 2017 Sep;19(9):672-683. doi: 10.1016/j.neo.2017.06.002. Epub 2017 Aug 1.


XIAP RING domain mediates miR-4295 expression and subsequently inhibiting p63α protein translation and promoting transformation of bladder epithelial cells.

Jin H, Xu J, Guo X, Huang H, Li J, Peng M, Zhu J, Tian Z, Wu XR, Tang MS, Huang C.

Oncotarget. 2016 Aug 30;7(35):56540-56557. doi: 10.18632/oncotarget.10645.


Inhibition of PHLPP2/cyclin D1 protein translation contributes to the tumor suppressive effect of NFκB2 (p100).

Xu J, Wang Y, Hua X, Xu J, Tian Z, Jin H, Li J, Wu XR, Huang C.

Oncotarget. 2016 Jun 7;7(23):34112-30. doi: 10.18632/oncotarget.8746.

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