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Items: 1 to 20 of 21

1.

A multi-center screening trial of rasagiline in patients with amyotrophic lateral sclerosis: Possible mitochondrial biomarker target engagement.

Macchi Z, Wang Y, Moore D, Katz J, Saperstein D, Walk D, Simpson E, Genge A, Bertorini T, Fernandes JA, Swenson A, Elman L, Dimachkie M, Herbelin L, Miller J, Lu J, Wilkins H, Swerdlow RH, Statland J, Barohn R; Western ALS (WALS) Rasagiline Study Group.

Amyotroph Lateral Scler Frontotemporal Degener. 2015;16(5-6):345-52. doi: 10.3109/21678421.2015.1026826. Epub 2015 Apr 2.

2.

Effect of one month duration ketogenic and non-ketogenic high fat diets on mouse brain bioenergetic infrastructure.

Selfridge JE, Wilkins HM, E L, Carl SM, Koppel S, Funk E, Fields T, Lu J, Tang EP, Slawson C, Wang W, Zhu H, Swerdlow RH.

J Bioenerg Biomembr. 2015 Apr;47(1-2):1-11. doi: 10.1007/s10863-014-9570-z. Epub 2014 Aug 8.

3.

Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis.

Wilkins HM, Harris JL, Carl SM, E L, Lu J, Eva Selfridge J, Roy N, Hutfles L, Koppel S, Morris J, Burns JM, Michaelis ML, Michaelis EK, Brooks WM, Swerdlow RH.

Hum Mol Genet. 2014 Dec 15;23(24):6528-41. doi: 10.1093/hmg/ddu371. Epub 2014 Jul 15.

4.

Altering O-linked β-N-acetylglucosamine cycling disrupts mitochondrial function.

Tan EP, Villar MT, E L, Lu J, Selfridge JE, Artigues A, Swerdlow RH, Slawson C.

J Biol Chem. 2014 May 23;289(21):14719-30. doi: 10.1074/jbc.M113.525790. Epub 2014 Apr 8.

5.

Lactate administration reproduces specific brain and liver exercise-related changes.

E L, Lu J, Selfridge JE, Burns JM, Swerdlow RH.

J Neurochem. 2013 Oct;127(1):91-100. doi: 10.1111/jnc.12394. Epub 2013 Aug 26.

6.

Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines.

Silva DF, Selfridge JE, Lu J, E L, Roy N, Hutfles L, Burns JM, Michaelis EK, Yan S, Cardoso SM, Swerdlow RH.

Hum Mol Genet. 2013 Oct 1;22(19):3931-46. doi: 10.1093/hmg/ddt247. Epub 2013 Jun 4.

7.

Glycolysis-respiration relationships in a neuroblastoma cell line.

Swerdlow RH, E L, Aires D, Lu J.

Biochim Biophys Acta. 2013 Apr;1830(4):2891-8. doi: 10.1016/j.bbagen.2013.01.002. Epub 2013 Jan 10.

8.

Effect of cholinergic signaling on neuronal cell bioenergetics.

Lu J, E L, Roy N, Hutfles L, Selfridge E, Funk E, Burns JM, Swerdlow RH.

J Alzheimers Dis. 2013;33(4):1135-46. doi: 10.3233/JAD-2012-121822.

9.

Mitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic intervention.

Silva DF, Selfridge JE, Lu J, E L, Cardoso SM, Swerdlow RH.

Adv Pharmacol. 2012;64:83-126. doi: 10.1016/B978-0-12-394816-8.00003-9. Review.

10.

Effect of exercise on mouse liver and brain bioenergetic infrastructures.

E L, Lu J, Burns JM, Swerdlow RH.

Exp Physiol. 2013 Jan;98(1):207-19. doi: 10.1113/expphysiol.2012.066688. Epub 2012 May 21.

11.

Role of mitochondrial homeostasis and dynamics in Alzheimer's disease.

Selfridge JE, E L, Lu J, Swerdlow RH.

Neurobiol Dis. 2013 Mar;51:3-12. doi: 10.1016/j.nbd.2011.12.057. Epub 2012 Jan 10. Review.

12.

Potentiation of dietary restriction-induced lifespan extension by polyphenols.

Aires DJ, Rockwell G, Wang T, Frontera J, Wick J, Wang W, Tonkovic-Capin M, Lu J, E L, Zhu H, Swerdlow RH.

Biochim Biophys Acta. 2012 Apr;1822(4):522-6. doi: 10.1016/j.bbadis.2012.01.005. Epub 2012 Jan 11.

13.

Reduced mitochondria cytochrome oxidase activity in adult children of mothers with Alzheimer's disease.

Mosconi L, de Leon M, Murray J, E L, Lu J, Javier E, McHugh P, Swerdlow RH.

J Alzheimers Dis. 2011;27(3):483-90. doi: 10.3233/JAD-2011-110866.

14.

Ncb5or deficiency increases fatty acid catabolism and oxidative stress.

Xu M, Wang W, Frontera JR, Neely MC, Lu J, Aires D, Hsu FF, Turk J, Swerdlow RH, Carlson SE, Zhu H.

J Biol Chem. 2011 Apr 1;286(13):11141-54. doi: 10.1074/jbc.M110.196543. Epub 2011 Feb 7.

15.

Alternate day fasting impacts the brain insulin-signaling pathway of young adult male C57BL/6 mice.

Lu J, E L, Wang W, Frontera J, Zhu H, Wang WT, Lee P, Choi IY, Brooks WM, Burns JM, Aires D, Swerdlow RH.

J Neurochem. 2011 Apr;117(1):154-63. doi: 10.1111/j.1471-4159.2011.07184.x. Epub 2011 Feb 9.

16.

Polymorphic variation in cytochrome oxidase subunit genes.

Lu J, Wang K, Rodova M, Esteves R, Berry D, E L, Crafter A, Barrett M, Cardoso SM, Onyango I, Parker WD, Fontes J, Burns JM, Swerdlow RH.

J Alzheimers Dis. 2010;21(1):141-54. doi: 10.3233/JAD-2010-100123.

17.

Regulation of neuron mitochondrial biogenesis and relevance to brain health.

Onyango IG, Lu J, Rodova M, Lezi E, Crafter AB, Swerdlow RH.

Biochim Biophys Acta. 2010 Jan;1802(1):228-34. doi: 10.1016/j.bbadis.2009.07.014. Epub 2009 Aug 11. Review.

18.

MEK1/2 inhibitors potentiate UCN-01 lethality in human multiple myeloma cells through a Bim-dependent mechanism.

Pei XY, Dai Y, Tenorio S, Lu J, Harada H, Dent P, Grant S.

Blood. 2007 Sep 15;110(6):2092-101. Epub 2007 May 31.

19.
20.

Angiotensin IV enhances phosphorylation of 4EBP1 by multiple signaling events in lung endothelial cells.

Lu J, Zhang J, Block ER, Patel JM.

Mol Cell Biochem. 2005 Jul;275(1-2):181-8.

PMID:
16342424

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