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Items: 1 to 20 of 30


Prenatal genetic analysis and differential pregnancy outcomes of two de novo cases showing mosaic isodicentric Y chromosome.

He S, Xi H, Chen J, Wang D, Pang J, Hu J, Liu Q, Jia Z, Wang H.

Mol Cytogenet. 2020 Feb 11;13:7. doi: 10.1186/s13039-020-0472-y. eCollection 2020.


Seasonal shifts in the assembly dynamics of benthic macroinvertebrate and diatom communities in a subtropical river.

Wang J, Hu J, Tang T, Heino J, Jiang X, Li Z, Xie Z.

Ecol Evol. 2020 Jan 3;10(2):692-704. doi: 10.1002/ece3.5904. eCollection 2020 Jan.


Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy.

Degirmenci U, Wang M, Hu J.

Cells. 2020 Jan 13;9(1). pii: E198. doi: 10.3390/cells9010198. Review.


Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods.

Yap J, Yuan J, Tee ZH, Huang X, Ng WH, Hu J.

J Vis Exp. 2019 Jul 17;(149). doi: 10.3791/59795.


[Identification of a de novo interstitial 21q22.12q22.13 deletion in a patient with intellectual disability].

Peng Y, Jia Z, Pang J, Hu J, Xi H, Wang H.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2019 Jul 10;36(7):704-707. doi: 10.3760/cma.j.issn.1003-9406.2019.07.012. Chinese.


IL13RA2 Is Differentially Regulated in Papillary Thyroid Carcinoma vs Follicular Thyroid Carcinoma.

Chong ST, Tan KM, Kok CYL, Guan SP, Lai SH, Lim C, Hu J, Sturgis C, Eng C, Lam PYP, Ngeow J.

J Clin Endocrinol Metab. 2019 Nov 1;104(11):5573-5584. doi: 10.1210/jc.2019-00040.


Assessment of PARP4 as a candidate breast cancer susceptibility gene.

Prawira A, Munusamy P, Yuan J, Chan CHT, Koh GL, Shuen TWH, Hu J, Yap YS, Tan MH, Ang P, Lee ASG.

Breast Cancer Res Treat. 2019 Aug;177(1):145-153. doi: 10.1007/s10549-019-05286-w. Epub 2019 May 22.


[Prenatal diagnosis of monochorionic-diamniotic twins discordant for 45,X/46,XX mosaicism].

Hu J, Xi H, Ma N, Pang J, Luo Y, Jia Z, Wang H.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2019 Mar 10;36(3):260-262. doi: 10.3760/cma.j.issn.1003-9406.2019.03.017. Chinese.


Iron Homeostasis Determines Fate of Human Pluripotent Stem Cells Via Glycerophospholipids-Epigenetic Circuit.

Han Z, Yu Y, Xu J, Bao Z, Xu Z, Hu J, Yu M, Bamba D, Ma W, Ding F, Zhang L, Jin M, Yan G, Huang Q, Wang X, Hua B, Yang F, Li Y, Lei L, Cao N, Pan Z, Cai B.

Stem Cells. 2019 Apr;37(4):489-503. doi: 10.1002/stem.2967. Epub 2019 Jan 28.


Activating mutations in MEK1 enhance homodimerization and promote tumorigenesis.

Yuan J, Ng WH, Tian Z, Yap J, Baccarini M, Chen Z, Hu J.

Sci Signal. 2018 Oct 30;11(554). pii: eaar6795. doi: 10.1126/scisignal.aar6795.


The AMPK inhibitor overcomes the paradoxical effect of RAF inhibitors through blocking phospho-Ser-621 in the C terminus of CRAF.

Yuan J, Ng WH, Yap J, Chia B, Huang X, Wang M, Hu J.

J Biol Chem. 2018 Sep 14;293(37):14276-14284. doi: 10.1074/jbc.RA118.004597. Epub 2018 Jul 20.


The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutants.

Yuan J, Ng WH, Lam PYP, Wang Y, Xia H, Yap J, Guan SP, Lee ASG, Wang M, Baccarini M, Hu J.

Oncogene. 2018 Oct;37(43):5719-5734. doi: 10.1038/s41388-018-0365-2. Epub 2018 Jun 21.


Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration.

Xu X, Wang X, Todd EM, Jaeger ER, Vella JL, Mooren OL, Feng Y, Hu J, Cooper JA, Morley SC, Huang YH.

J Immunol. 2016 Sep 1;197(5):1683-91. doi: 10.4049/jimmunol.1600874. Epub 2016 Jul 27.


A de novo duplication of chromosome 9q34.13-qter in a fetus with Tetralogy of Fallot Syndrome.

Liu J, Hu H, Ma N, Jia Z, Zhou Y, Hu J, Wang H.

Mol Cytogenet. 2016 Jul 25;9:54. doi: 10.1186/s13039-016-0267-3. eCollection 2016.


[Genetic analysis for 2 females carrying idic(Y)(p) and with sex development disorders].

Zhang Y, Wang H, Jia Z, Hu J, Cao W, Tan Y.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2016 Jun;33(3):335-9. doi: 10.3760/cma.j.issn.1003-9406.2016.03.013. Chinese.


A numerical solution of a singular boundary value problem arising in boundary layer theory.

Hu J.

Springerplus. 2016 Feb 27;5:198. doi: 10.1186/s40064-016-1835-z. eCollection 2016.


Albumin-associated free fatty acids induce macropinocytosis in podocytes.

Chung JJ, Huber TB, Gödel M, Jarad G, Hartleben B, Kwoh C, Keil A, Karpitskiy A, Hu J, Huh CJ, Cella M, Gross RW, Miner JH, Shaw AS.

J Clin Invest. 2015 Jun;125(6):2307-16. doi: 10.1172/JCI79641. Epub 2015 Apr 27.


[Abnormal expression of PEX10 gene may be related to epilepsy associated with 1p36 copy number variations].

Zhang Y, Xu F, Tan Y, Hu J, Wang H.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2015 Feb;32(1):6-10. doi: 10.3760/cma.j.issn.1003-9406.2015.01.002. Chinese.


Kinase regulation by hydrophobic spine assembly in cancer.

Hu J, Ahuja LG, Meharena HS, Kannan N, Kornev AP, Taylor SS, Shaw AS.

Mol Cell Biol. 2015 Jan;35(1):264-76. doi: 10.1128/MCB.00943-14. Epub 2014 Oct 27.


Calmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production.

Wang X, Boyken SE, Hu J, Xu X, Rimer RP, Shea MA, Shaw AS, Andreotti AH, Huang YH.

Sci Signal. 2014 Aug 5;7(337):ra74. doi: 10.1126/scisignal.2005147.

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