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Mechanism and regulation of ferrous heme-nitric oxide (NO) oxidation in NO synthases.

Tejero J, Hunt AP, Santolini J, Lehnert N, Stuehr DJ.

J Biol Chem. 2019 May 10;294(19):7904-7916. doi: 10.1074/jbc.RA119.007810. Epub 2019 Mar 29.


Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation

Tejero J, Shiva S, Gladwin MT.

Physiol Rev. 2019 Jan 1;99(1):311-379. doi: 10.1152/physrev.00036.2017. Review.


Nitrosyl Myoglobins and Their Nitrite Precursors: Crystal Structural and Quantum Mechanics and Molecular Mechanics Theoretical Investigations of Preferred Fe -NO Ligand Orientations in Myoglobin Distal Pockets.

Wang B, Shi Y, Tejero J, Powell SM, Thomas LM, Gladwin MT, Shiva S, Zhang Y, Richter-Addo GB.

Biochemistry. 2018 Aug 14;57(32):4788-4802. doi: 10.1021/acs.biochem.8b00542. Epub 2018 Jul 27.


Thrombospondin-1 protects against pathogen-induced lung injury by limiting extracellular matrix proteolysis.

Qu Y, Olonisakin T, Bain W, Zupetic J, Brown R, Hulver M, Xiong Z, Tejero J, Shanks RM, Bomberger JM, Cooper VS, Zegans ME, Ryu H, Han J, Pilewski J, Ray A, Cheng Z, Ray P, Lee JS.

JCI Insight. 2018 Feb 8;3(3). pii: 96914. doi: 10.1172/jci.insight.96914. eCollection 2018 Feb 8.


A cross-domain charge interaction governs the activity of NO synthase.

Haque MM, Tejero J, Bayachou M, Kenney CT, Stuehr DJ.

J Biol Chem. 2018 Mar 23;293(12):4545-4554. doi: 10.1074/jbc.RA117.000635. Epub 2018 Feb 2.


Cytoglobin at the Crossroads of Vascular Remodeling.

Amdahl MB, DeMartino AW, Tejero J, Gladwin MT.

Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1803-1805. doi: 10.1161/ATVBAHA.117.310058. No abstract available.


Efficient Reduction of Vertebrate Cytoglobins by the Cytochrome b5/Cytochrome b5 Reductase/NADH System.

Amdahl MB, Sparacino-Watkins CE, Corti P, Gladwin MT, Tejero J.

Biochemistry. 2017 Aug 1;56(30):3993-4004. doi: 10.1021/acs.biochem.7b00224. Epub 2017 Jul 19.


Reply: Carbon Monoxide Exposure in Workplaces, Including Coffee Processing Facilities.

Rose JJ, Wang L, Xu Q, McTiernan CF, Shiva S, Tejero J, Gladwin MT.

Am J Respir Crit Care Med. 2017 Oct 15;196(8):1081-1082. doi: 10.1164/rccm.201704-0773LE. No abstract available.


Hemoglobin inhibits albumin uptake by proximal tubule cells: implications for sickle cell disease.

Eshbach ML, Kaur A, Rbaibi Y, Tejero J, Weisz OA.

Am J Physiol Cell Physiol. 2017 Jun 1;312(6):C733-C740. doi: 10.1152/ajpcell.00021.2017. Epub 2017 Mar 29.


Reply: Better Studies Are Needed to Guide Treatment of Carbon Monoxide Poisoning.

Rose JJ, Wang L, Xu Q, McTiernan CF, Shiva S, Tejero J, Gladwin MT.

Am J Respir Crit Care Med. 2017 Mar 1;195(5):694-695. doi: 10.1164/rccm.201612-2463LE. No abstract available.


Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning.

Azarov I, Wang L, Rose JJ, Xu Q, Huang XN, Belanger A, Wang Y, Guo L, Liu C, Ucer KB, McTiernan CF, O'Donnell CP, Shiva S, Tejero J, Kim-Shapiro DB, Gladwin MT.

Sci Transl Med. 2016 Dec 7;8(368):368ra173.


Carbon Monoxide Poisoning: Pathogenesis, Management, and Future Directions of Therapy.

Rose JJ, Wang L, Xu Q, McTiernan CF, Shiva S, Tejero J, Gladwin MT.

Am J Respir Crit Care Med. 2017 Mar 1;195(5):596-606. doi: 10.1164/rccm.201606-1275CI. Review. Erratum in: Am J Respir Crit Care Med. 2017 Aug 1;196 (3):398-399.


Globin X is a six-coordinate globin that reduces nitrite to nitric oxide in fish red blood cells.

Corti P, Xue J, Tejero J, Wajih N, Sun M, Stolz DB, Tsang M, Kim-Shapiro DB, Gladwin MT.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8538-43. doi: 10.1073/pnas.1522670113. Epub 2016 Jul 12.


Peroxidase activation of cytoglobin by anionic phospholipids: Mechanisms and consequences.

Tejero J, Kapralov AA, Baumgartner MP, Sparacino-Watkins CE, Anthonymutu TS, Vlasova II, Camacho CJ, Gladwin MT, Bayir H, Kagan VE.

Biochim Biophys Acta. 2016 May;1861(5):391-401. doi: 10.1016/j.bbalip.2016.02.022. Epub 2016 Feb 27.


Characterization of zebrafish neuroglobin and cytoglobins 1 and 2: Zebrafish cytoglobins provide insights into the transition from six-coordinate to five-coordinate globins.

Corti P, Ieraci M, Tejero J.

Nitric Oxide. 2016 Feb 29;53:22-34. doi: 10.1016/j.niox.2015.12.004. Epub 2015 Dec 22.


Correction to Exploring the Mechanisms of the Reductase Activity of Neuroglobin by Site-Directed Mutagenesis of the Heme Distal Pocket.

Tejero J, Sparacino-Watkins CE, Ragireddy V, Frizzell S, Gladwin MT.

Biochemistry. 2015 Jun 16;54(23):3716. doi: 10.1021/acs.biochem.5b00579. Epub 2015 Jun 8. No abstract available.


Inorganic nitrite improves components of the metabolic syndrome independent of weight change in a murine model of obesity and insulin resistance.

Singamsetty S, Watanabe Y, Guo L, Corey C, Wang Y, Tejero J, McVerry BJ, Gladwin MT, Shiva S, O'Donnell CP.

J Physiol. 2015 Jul 15;593(14):3135-45. doi: 10.1113/JP270386. Epub 2015 Jun 25.


Ebulin from dwarf elder (Sambucus ebulus L.): a mini-review.

Jiménez P, Tejero J, Cordoba-Diaz D, Quinto EJ, Garrosa M, Gayoso MJ, Girbés T.

Toxins (Basel). 2015 Feb 25;7(3):648-58. doi: 10.3390/toxins7030648. Review.


Toxicity of the anti-ribosomal Lectin Ebulin f in lungs and intestines in elderly mice.

Garrosa M, Jiménez P, Tejero J, Cabrero P, Cordoba-Diaz D, Quinto EJ, Gayoso MJ, Girbés T.

Toxins (Basel). 2015 Feb 2;7(2):367-79. doi: 10.3390/toxins7020367.


Elderberries: a source of ribosome-inactivating proteins with lectin activity.

Tejero J, Jiménez P, Quinto EJ, Cordoba-Diaz D, Garrosa M, Cordoba-Diaz M, Gayoso MJ, Girbés T.

Molecules. 2015 Jan 30;20(2):2364-87. doi: 10.3390/molecules20022364. Review.

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