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Items: 1 to 20 of 34


Pharmacological Utilization of Bergamottin, Derived from Grapefruits, in Cancer Prevention and Therapy.

Ko JH, Arfuso F, Sethi G, Ahn KS.

Int J Mol Sci. 2018 Dec 14;19(12). pii: E4048. doi: 10.3390/ijms19124048. Review.


Casticin inhibits growth and enhances ionizing radiation-induced apoptosis through the suppression of STAT3 signaling cascade.

Lee JH, Kim C, Ko JH, Jung YY, Jung SH, Kim E, Kong M, Chinnathambi A, Alahmadi TA, Alharbi SA, Sethi G, Ahn KS.

J Cell Biochem. 2018 Dec 5. doi: 10.1002/jcb.28259. [Epub ahead of print]


Bergamottin Suppresses Metastasis of Lung Cancer Cells through Abrogation of Diverse Oncogenic Signaling Cascades and Epithelial-to-Mesenchymal Transition.

Ko JH, Nam D, Um JY, Jung SH, Sethi G, Ahn KS.

Molecules. 2018 Jul 2;23(7). pii: E1601. doi: 10.3390/molecules23071601.


Bergamottin Inhibits Adipogenesis in 3T3-L1 Cells and Weight Regulation in Diet-Induced Obese Mice.

Ko JH, Nam D, Um JY, Jung SH, Ahn KS.

Am J Chin Med. 2018;46(3):601-615. doi: 10.1142/S0192415X18500313. Epub 2018 Apr 4.


The Application of Embelin for Cancer Prevention and Therapy.

Ko JH, Lee SG, Yang WM, Um JY, Sethi G, Mishra S, Shanmugam MK, Ahn KS.

Molecules. 2018 Mar 9;23(3). pii: E621. doi: 10.3390/molecules23030621. Review.


The Role of Resveratrol in Cancer Therapy.

Ko JH, Sethi G, Um JY, Shanmugam MK, Arfuso F, Kumar AP, Bishayee A, Ahn KS.

Int J Mol Sci. 2017 Dec 1;18(12). pii: E2589. doi: 10.3390/ijms18122589. Review.


2,5-Dihydroxyacetophenone Induces Apoptosis of Multiple Myeloma Cells by Regulating the MAPK Activation Pathway.

Ko JH, Lee JH, Jung SH, Lee SG, Chinnathambi A, Alharbi SA, Yang WM, Um JY, Sethi G, Ahn KS.

Molecules. 2017 Jul 11;22(7). pii: E1157. doi: 10.3390/molecules22071157.


Korean Red Ginseng Extract Enhances the Anticancer Effects of Sorafenib through Abrogation of CREB and c-Jun Activation in Renal Cell Carcinoma.

Kim C, Lee JH, Baek SH, Ko JH, Nam D, Ahn KS.

Phytother Res. 2017 Jul;31(7):1078-1089. doi: 10.1002/ptr.5829. Epub 2017 May 22.


Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti-Metastatic Effects in Human Hepatocellular Carcinoma Cells through the Modulation of Diverse Cell Signaling Cascades.

Lee H, Baek SH, Lee JH, Kim C, Ko JH, Lee SG, Chinnathambi A, Alharbi SA, Yang WM, Um JY, Sethi G, Ahn KS.

Int J Mol Sci. 2017 May 19;18(5). pii: E1095. doi: 10.3390/ijms18051095.


Ginkgolic Acid C 17:1, Derived from Ginkgo biloba Leaves, Suppresses Constitutive and Inducible STAT3 Activation through Induction of PTEN and SHP-1 Tyrosine Phosphatase.

Baek SH, Lee JH, Kim C, Ko JH, Ryu SH, Lee SG, Yang WM, Um JY, Chinnathambi A, Alharbi SA, Sethi G, Ahn KS.

Molecules. 2017 Feb 13;22(2). pii: E276. doi: 10.3390/molecules22020276.


Ginkgolic Acid Inhibits Invasion and Migration and TGF-β-Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation.

Baek SH, Ko JH, Lee JH, Kim C, Lee H, Nam D, Lee J, Lee SG, Yang WM, Um JY, Sethi G, Ahn KS.

J Cell Physiol. 2017 Feb;232(2):346-354. doi: 10.1002/jcp.25426. Epub 2016 Jun 2.


Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancer.

Lee JH, Kim C, Baek SH, Ko JH, Lee SG, Yang WM, Um JY, Sethi G, Ahn KS.

Oncotarget. 2017 Mar 14;8(11):17700-17711. doi: 10.18632/oncotarget.10775.


3-Formylchromone inhibits proliferation and induces apoptosis of multiple myeloma cells by abrogating STAT3 signaling through the induction of PIAS3.

Ko JH, Ho Baek S, Nam D, Chung WS, Lee SG, Lee J, Mo Yang W, Um JY, Seok Ahn K.

Immunopharmacol Immunotoxicol. 2016 Oct;38(5):334-43. doi: 10.1080/08923973.2016.1203928. Epub 2016 Jul 7.


Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells.

Baek SH, Ko JH, Lee H, Jung J, Kong M, Lee JW, Lee J, Chinnathambi A, Zayed ME, Alharbi SA, Lee SG, Shim BS, Sethi G, Kim SH, Yang WM, Um JY, Ahn KS.

Phytomedicine. 2016 May 15;23(5):566-77. doi: 10.1016/j.phymed.2016.02.011. Epub 2016 Feb 27.


Ginkgetin Blocks Constitutive STAT3 Activation and Induces Apoptosis through Induction of SHP-1 and PTEN Tyrosine Phosphatases.

Baek SH, Lee JH, Ko JH, Lee H, Nam D, Lee SG, Yang WM, Um JY, Lee J, Kim SH, Shim BS, Ahn KS.

Phytother Res. 2016 Apr;30(4):567-76. doi: 10.1002/ptr.5557. Epub 2016 Jan 12.


Embelin Inhibits Invasion and Migration of MDA-MB-231 Breast Cancer Cells by Suppression of CXC Chemokine Receptor 4, Matrix Metalloproteinases-9/2, and Epithelial-Mesenchymal Transition.

Lee H, Ko JH, Baek SH, Nam D, Lee SG, Lee J, Yang WM, Um JY, Kim SH, Shim BS, Ahn KS.

Phytother Res. 2016 Jun;30(6):1021-32. doi: 10.1002/ptr.5612. Epub 2016 Mar 31.


MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification.

Kwon DH, Eom GH, Ko JH, Shin S, Joung H, Choe N, Nam YS, Min HK, Kook T, Yoon S, Kang W, Kim YS, Kim HS, Choi H, Koh JT, Kim N, Ahn Y, Cho HJ, Lee IK, Park DH, Suk K, Seo SB, Wissing ER, Mendrysa SM, Nam KI, Kook H.

Nat Commun. 2016 Feb 1;7:10492. doi: 10.1038/ncomms10492.


Ret finger protein mediates Pax7-induced ubiquitination of MyoD in skeletal muscle atrophy.

Joung H, Eom GH, Choe N, Lee HM, Ko JH, Kwon DH, Nam YS, Min H, Shin S, Kook J, Cho YK, Kim JC, Seo SB, Baik YH, Nam KI, Kook H.

Cell Signal. 2014 Oct;26(10):2240-8. doi: 10.1016/j.cellsig.2014.07.006. Epub 2014 Jul 12.


Right ventricular myocardial performance index is decreased with severe pressure-overload cardiac hypertrophy in young rats.

Ko JH, Eom GH, Cho HJ, Nam KI, Ma JS, Kook H, Cho YK.

Pediatr Cardiol. 2013 Oct;34(7):1556-66. doi: 10.1007/s00246-013-0678-4. Epub 2013 Mar 7.


Targeting of the osteoclastogenic RANKL-RANK axis prevents osteoporotic bone loss and soft tissue calcification in coxsackievirus B3-infected mice.

Lee K, Kim H, Park HS, Kim KJ, Song H, Shin HI, Kim HS, Seo D, Kook H, Ko JH, Jeong D.

J Immunol. 2013 Feb 15;190(4):1623-30. doi: 10.4049/jimmunol.1201479. Epub 2013 Jan 9.

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