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Incretin therapy for diabetes mellitus type 2.

Holst JJ.

Curr Opin Endocrinol Diabetes Obes. 2019 Dec 4. doi: 10.1097/MED.0000000000000516. [Epub ahead of print]


Habitual activity associates with lower fasting and greater glucose-induced GLP-1 response in men.

Janus C, Vistisen D, Amadid H, Witte DR, Lauritzen T, Brage S, Bjerregaard AL, Hansen T, Holst JJ, Jørgensen ME, Pedersen O, Færch K, Torekov S.

Endocr Connect. 2019 Dec 1. pii: EC-19-0408.R2. doi: 10.1530/EC-19-0408. [Epub ahead of print]


Correction to: Effects of glucagon-like peptide 1 analogs on alcohol intake in alcohol-preferring vervet monkeys.

Thomsen M, Holst JJ, Molander A, Linnet K, Ptito M, Fink-Jensen A.

Psychopharmacology (Berl). 2019 Nov 25. doi: 10.1007/s00213-019-05374-1. [Epub ahead of print]


A Low Dose of Pasireotide Prevents Hypoglycemia in Roux-en-Y Gastric Bypass-Operated Individuals.

Øhrstrøm CC, Hansen DL, Kielgast UL, Hartmann B, Holst JJ, Worm D.

Obes Surg. 2019 Nov 10. doi: 10.1007/s11695-019-04248-x. [Epub ahead of print]


A Pilot Study Showing Acute Inhibitory Effect of GLP-1 on the Bone Resorption Marker CTX in Humans.

Nissen A, Marstrand S, Skov-Jeppesen K, Bremholm L, Hornum M, Andersen UB, Holst JJ, Rosenkilde MM, Hartmann B.

JBMR Plus. 2019 Aug 23;3(10):e10209. doi: 10.1002/jbm4.10209. eCollection 2019 Oct.


Protocol for a randomised controlled trial of the combined effects of the GLP-1 receptor agonist liraglutide and exercise on maintenance of weight loss and health after a very low-calorie diet.

Jensen SBK, Lundgren JR, Janus C, Juhl CR, Olsen LM, Rosenkilde M, Holst JJ, Stallknecht BM, Madsbad S, Torekov SS.

BMJ Open. 2019 Nov 2;9(11):e031431. doi: 10.1136/bmjopen-2019-031431.


Effects of Exercise Training and IL-6 Receptor Blockade on Gastric Emptying and GLP-1 Secretion in Obese Humans: Secondary Analyses From a Double Blind Randomized Clinical Trial.

Lehrskov LL, Christensen RH, Wedell-Neergaard AS, Legaard GE, Dorph E, Larsen MK, Henneberg M, Launbo N, Fagerlind SR, Seide SK, Nymand S, Ball M, Vinum N, Dahl C, Wewer Albrechtsen NJ, Holst JJ, Ried-Larsen M, Rosenmeier JB, Krogh-Madsen R, Karstoft K, Pedersen BK, Ellingsgaard H.

Front Physiol. 2019 Oct 4;10:1249. doi: 10.3389/fphys.2019.01249. eCollection 2019.


Ghrelin does not directly stimulate secretion of glucagon-like peptide-1.

Jepsen SL, Vestergaard ET, Larraufie P, Gribble FM, Reimann F, Jørgensen JOL, Holst JJ, Kuhre RE.

J Clin Endocrinol Metab. 2019 Oct 14. pii: dgz046. doi: 10.1210/clinem/dgz046. [Epub ahead of print]


Gluco-metabolic effects of oral and intravenous alcohol administration in men.

Lanng ARR, Gasbjerg LS, Bergmann NC, Bermann S, Helsted MM, Gillum MP, Hartmann B, Holst JJ, Vilsbøll T, Knop FK.

Endocr Connect. 2019 Sep 1. pii: EC-19-0317.R1. doi: 10.1530/EC-19-0317. [Epub ahead of print]


Short-chain fatty acids and regulation of pancreatic endocrine secretion in mice.

Ørgaard A, Jepsen SL, Holst JJ.

Islets. 2019;11(5):103-111. doi: 10.1080/19382014.2019.1587976. Epub 2019 Aug 30.


Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats.

Baldassano S, Gasbjerg LS, Kizilkaya HS, Rosenkilde MM, Holst JJ, Hartmann B.

Front Endocrinol (Lausanne). 2019 Aug 6;10:492. doi: 10.3389/fendo.2019.00492. eCollection 2019.


The imprinted gene Delta like non-canonical notch ligand 1 (Dlk1) associates with obesity and triggers insulin resistance through inhibition of skeletal muscle glucose uptake.

Jensen CH, Kosmina R, Rydén M, Baun C, Hvidsten S, Andersen MS, Christensen LL, Gastaldelli A, Marraccini P, Arner P, Jørgensen CD, Laborda J, Holst JJ, Andersen DC.

EBioMedicine. 2019 Aug;46:368-380. doi: 10.1016/j.ebiom.2019.07.070. Epub 2019 Aug 3.


Gastric Emptying and Distal Gastrectomy Independently Enhance Postprandial Glucagon-Like Peptide-1 Release After a Mixed Meal and Improve Glycemic Control in Subjects Having Undergone Pancreaticoduodenectomy.

Steiner E, Breuer R, Kazianka L, Wewalka M, Stimpfl T, Reiter B, Holst JJ, Miholic J.

Pancreas. 2019 Aug;48(7):953-957. doi: 10.1097/MPA.0000000000001361.


Pros and cons of Roux en-Y gastric bypass surgery in obese patients with type 2 diabetes.

Justinussen T, Madsbad S, Holst JJ, Bojsen-Møller KN.

Expert Rev Endocrinol Metab. 2019 Jul;14(4):243-257. doi: 10.1080/17446651.2019.1628639. Epub 2019 Jun 19.


The diurnal variation of bone formation is attenuated in adult patients with type 2 diabetes.

Hygum K, Starup-Linde JK, Harsløf T, Joergensen NR, Hartmann B, Holst JJ, Langdahl B.

Eur J Endocrinol. 2019 Jun 1. pii: EJE-19-0309.R1. doi: 10.1530/EJE-19-0309. [Epub ahead of print]


Which to choose, an oral or an injectable glucagon-like peptide-1 receptor agonist?

Holst JJ.

Lancet. 2019 Jul 6;394(10192):4-6. doi: 10.1016/S0140-6736(19)31350-9. Epub 2019 Jun 8. No abstract available.


Liraglutide improves the beta-cell function without increasing insulin secretion during a mixed meal in patients, who exhibit well-controlled type 2 diabetes and coronary artery disease.

Anholm C, Kumarathurai P, Jürs A, Pedersen LR, Nielsen OW, Kristiansen OP, Fenger M, Holst JJ, Madsbad S, Sajadieh A, Haugaard SB.

Diabetol Metab Syndr. 2019 May 31;11:42. doi: 10.1186/s13098-019-0438-6. eCollection 2019.


Postprandial hypoglycaemia after Roux-en-Y gastric bypass and the effects of acarbose, sitagliptin, verapamil, liraglutide and pasireotide.

Øhrstrøm CC, Worm D, Højager A, Andersen D, Holst JJ, Kielgast UL, Hansen DL.

Diabetes Obes Metab. 2019 Sep;21(9):2142-2151. doi: 10.1111/dom.13796. Epub 2019 Jun 24.


From the Incretin Concept and the Discovery of GLP-1 to Today's Diabetes Therapy.

Holst JJ.

Front Endocrinol (Lausanne). 2019 Apr 26;10:260. doi: 10.3389/fendo.2019.00260. eCollection 2019. Review.


GIP-induced vasodilation in human adipose tissue involves capillary recruitment.

Asmar M, Asmar A, Simonsen L, Dela F, Holst JJ, Bülow J.

Endocr Connect. 2019 May 1. pii: EC-19-0144.R1. doi: 10.1530/EC-19-0144. [Epub ahead of print]

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