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Reduced GLP-1 Secretion at 30 Minutes After a 75g Oral Glucose Load is Observed in Gestational Diabetes Mellitus: A Prospective Cohort Study.

Sukumar N, Bagias C, Goljan I, Weldeselassie Y, Gharanei S, Tan BK, Holst JJ, Saravanan P.

Diabetes. 2018 Sep 19. pii: db180254. doi: 10.2337/db18-0254. [Epub ahead of print]


Acute Effects of Dietary Carbohydrate Restriction on Glycemia, Lipemia and Appetite Regulating Hormones in Normal-Weight to Obese Subjects.

Samkani A, Skytte MJ, Thomsen MN, Astrup A, Deacon CF, Holst JJ, Madsbad S, Rehfeld JF, Krarup T, Haugaard SB.

Nutrients. 2018 Sep 12;10(9). pii: E1285. doi: 10.3390/nu10091285.


No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course.

Mikkelsen KH, Vilsbøll T, Holst JJ, Hartmann B, Knop FK, Frost M.

BMC Endocr Disord. 2018 Sep 4;18(1):60. doi: 10.1186/s12902-018-0291-x.


Renoprotective effects of dulaglutide in patients with T2DM and CKD.

Sorensen CM, Holst JJ.

Nat Rev Nephrol. 2018 Aug 31. doi: 10.1038/s41581-018-0055-x. [Epub ahead of print] No abstract available.


Glucose Tolerance Tests and Osteocalcin Responses in Healthy People.

Starup-Linde J, Westberg-Rasmussen S, Lykkeboe S, Handberg A, Hartmann B, Holst JJ, Hermansen K, Vestergaard P, Gregersen S.

Front Endocrinol (Lausanne). 2018 Jul 13;9:356. doi: 10.3389/fendo.2018.00356. eCollection 2018.


Hyperosmolar duodenal saline infusion lowers circulating ghrelin and stimulates intestinal hormone release in young men.

Veedfald S, Wu T, Bound M, Grivell J, Hartmann B, Rehfeld JF, Deacon CF, Horowitz M, Holst JJ, Rayner CK.

J Clin Endocrinol Metab. 2018 Jul 20. doi: 10.1210/jc.2018-00699. [Epub ahead of print]


Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice.

Christiansen CB, Lind SJ, Svendsen B, Balk-Møller E, Dahlby T, Kuhre RE, Hartmann B, Mandrup-Poulsen T, Deacon CF, Wewer Albrechtsen NJ, Holst JJ.

Physiol Rep. 2018 Jul;6(13):e13788. doi: 10.14814/phy2.13788.


The Prebiotic Inulin Improves Substrate Metabolism and Promotes Short-Chain Fatty Acid Production in Overweight to Obese Men.

van der Beek CM, Canfora EE, Kip AM, Gorissen SHM, Olde Damink SWM, van Eijk HM, Holst JJ, Blaak EE, Dejong CHC, Lenaerts K.

Metabolism. 2018 Jun 25. pii: S0026-0495(18)30151-3. doi: 10.1016/j.metabol.2018.06.009. [Epub ahead of print]


Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine.

Petersen N, Frimurer TM, Pedersen MT, Egerod KL, Wewer Albrechtsen NJ, Holst JJ, Grapin-Botton A, Jensen KB, Schwartz TW.

Gastroenterology. 2018 Jun 20. pii: S0016-5085(18)34666-3. doi: 10.1053/j.gastro.2018.06.039. [Epub ahead of print]


Patients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor Agonist.

Iepsen EW, Zhang J, Thomsen HS, Hansen EL, Hollensted M, Madsbad S, Hansen T, Holst JJ, Holm JC, Torekov SS.

Cell Metab. 2018 Jul 3;28(1):23-32.e3. doi: 10.1016/j.cmet.2018.05.008. Epub 2018 May 31.


Gut hormone release after gastric bypass depends on the length of the biliopancreatic limb.

Patrício BG, Morais T, Guimarães M, Veedfald S, Hartmann B, Hilsted L, Holst JJ, Nora M, Monteiro MP.

Int J Obes (Lond). 2018 May 24. doi: 10.1038/s41366-018-0117-y. [Epub ahead of print]


Restoration of enteroendocrine and pancreatic function after internal hernia and short bowel syndrome in a young woman with gastric bypass - a 2-year follow-up.

Borghede M, Vinter-Jensen L, Rasmussen HH, Veedfald S, Rehfeld JF, Hartmann B, Holst JJ, Knop FK, Sonne DP.

Physiol Rep. 2018 May;6(9):e13686. doi: 10.14814/phy2.13686.


The effect of casein, hydrolyzed casein, and whey proteins on urinary and postprandial plasma metabolites in overweight and moderately obese human subjects.

Schmedes M, Bendtsen LQ, Gomes S, Liaset B, Holst JJ, Ritz C, Reitelseder S, Sjödin A, Astrup A, Young JF, Sundekilde UK, Bertram HC.

J Sci Food Agric. 2018 Apr 26. doi: 10.1002/jsfa.9103. [Epub ahead of print]


Older Subjects With β-Cell Dysfunction Have an Accentuated Incretin Release.

de Jesús Garduno-Garcia J, Gastaldelli A, DeFronzo RA, Lertwattanarak R, Holst JJ, Musi N.

J Clin Endocrinol Metab. 2018 Jul 1;103(7):2613-2619. doi: 10.1210/jc.2018-00260.


Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.

Kuhre RE, Wewer Albrechtsen NJ, Larsen O, Jepsen SL, Balk-Møller E, Andersen DB, Deacon CF, Schoonjans K, Reimann F, Gribble FM, Albrechtsen R, Hartmann B, Rosenkilde MM, Holst JJ.

Mol Metab. 2018 May;11:84-95. doi: 10.1016/j.molmet.2018.03.007. Epub 2018 Mar 17.


Is glucagon-like peptide-1 fully protected by the dipeptidyl peptidase 4 inhibitor sitagliptin when administered to patients with type 2 diabetes?

Andersen ES, Lund A, Bagger JI, Andreasen C, Grøndahl MF, Deacon CF, Hartmann B, Holst JJ, Knop FK, Vilsbøll T.

Diabetes Obes Metab. 2018 Aug;20(8):1937-1943. doi: 10.1111/dom.13321. Epub 2018 May 9.


A carbohydrate-reduced high-protein diet acutely decreases postprandial and diurnal glucose excursions in type 2 diabetes patients.

Samkani A, Skytte MJ, Kandel D, Kjaer S, Astrup A, Deacon CF, Holst JJ, Madsbad S, Rehfeld JF, Haugaard SB, Krarup T.

Br J Nutr. 2018 Apr;119(8):910-917. doi: 10.1017/S0007114518000521.


Effects of Smoking Versus Nonsmoking on Postprandial Glucose Metabolism in Heavy Smokers Compared With Nonsmokers.

Grøndahl MF, Bagger JI, Lund A, Faurschou A, Rehfeld JF, Holst JJ, Vilsbøll T, Knop FK.

Diabetes Care. 2018 Jun;41(6):1260-1267. doi: 10.2337/dc17-1818. Epub 2018 Mar 30.


Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses.

Engelbrechtsen L, Mahendran Y, Jonsson A, Gjesing AP, Weeke PE, Jørgensen ME, Færch K, Witte DR, Holst JJ, Jørgensen T, Grarup N, Pedersen O, Vestergaard H, Torekov S, Kanters JK, Hansen T.

BMC Genet. 2018 Mar 16;19(1):15. doi: 10.1186/s12863-018-0602-2.


The glucagon like peptide-2 'axis': Capacity for production and response following intestinal resection or repair of gastroschisis in infants.

Sigalet DL, Lam V, Brindle M, Boctor D, Wallace L, de Heuval E, Hartmann B, Holst JJ.

J Pediatr Surg. 2018 May;53(5):898-904. doi: 10.1016/j.jpedsurg.2018.02.012. Epub 2018 Feb 7.


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