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Items: 1 to 20 of 28

1.

Toxins as tools: Fingerprinting neuronal pharmacology.

Israel MR, Morgan M, Tay B, Deuis JR.

Neurosci Lett. 2018 Jul 13;679:4-14. doi: 10.1016/j.neulet.2018.02.001. Epub 2018 Feb 6. Review.

PMID:
29425731
2.

The E15R Point Mutation in Scorpion Toxin Cn2 Uncouples Its Depressant and Excitatory Activities on Human NaV1.6.

Israel MR, Thongyoo P, Deuis JR, Craik DJ, Vetter I, Durek T.

J Med Chem. 2018 Feb 22;61(4):1730-1736. doi: 10.1021/acs.jmedchem.7b01609. Epub 2018 Feb 3.

PMID:
29378414
3.

Role of complement anaphylatoxin receptors in a mouse model of acute burn-induced pain.

Morgan M, Deuis JR, Woodruff TM, Lewis RJ, Vetter I.

Mol Immunol. 2018 Feb;94:68-74. doi: 10.1016/j.molimm.2017.12.016. Epub 2017 Dec 21.

PMID:
29274925
4.

Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species.

Muttenthaler M, Andersson Å, Vetter I, Menon R, Busnelli M, Ragnarsson L, Bergmayr C, Arrowsmith S, Deuis JR, Chiu HS, Palpant NJ, O'Brien M, Smith TJ, Wray S, Neumann ID, Gruber CW, Lewis RJ, Alewood PF.

Sci Signal. 2017 Dec 5;10(508). pii: eaan3398. doi: 10.1126/scisignal.aan3398.

5.

Burn Pain: A Systematic and Critical Review of Epidemiology, Pathophysiology, and Treatment.

Morgan M, Deuis JR, Frøsig-Jørgensen M, Lewis RJ, Cabot PJ, Gray PD, Vetter I.

Pain Med. 2018 Apr 1;19(4):708-734. doi: 10.1093/pm/pnx228.

PMID:
29036469
6.

Methods Used to Evaluate Pain Behaviors in Rodents.

Deuis JR, Dvorakova LS, Vetter I.

Front Mol Neurosci. 2017 Sep 6;10:284. doi: 10.3389/fnmol.2017.00284. eCollection 2017.

7.

Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi.

Sousa SR, Wingerd JS, Brust A, Bladen C, Ragnarsson L, Herzig V, Deuis JR, Dutertre S, Vetter I, Zamponi GW, King GF, Alewood PF, Lewis RJ.

PLoS One. 2017 Sep 7;12(9):e0182848. doi: 10.1371/journal.pone.0182848. eCollection 2017.

8.

Corrigendum: Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a.

Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, Christie MJ, King GF, Alewood PF, Lewis RJ, Wood JN, Vetter I.

Sci Rep. 2017 May 26;7:46816. doi: 10.1038/srep46816. No abstract available.

9.

Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus.

Cardoso FC, Dekan Z, Smith JJ, Deuis JR, Vetter I, Herzig V, Alewood PF, King GF, Lewis RJ.

Br J Pharmacol. 2017 Aug;174(15):2528-2544. doi: 10.1111/bph.13865. Epub 2017 Jun 27.

10.

Sodium Channels and Venom Peptide Pharmacology.

Israel MR, Tay B, Deuis JR, Vetter I.

Adv Pharmacol. 2017;79:67-116. doi: 10.1016/bs.apha.2017.01.004. Epub 2017 Apr 8. Review.

PMID:
28528674
11.

Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities.

Dekan Z, Headey SJ, Scanlon M, Baldo BA, Lee TH, Aguilar MI, Deuis JR, Vetter I, Elliott AG, Amado M, Cooper MA, Alewood D, Alewood PF.

Angew Chem Int Ed Engl. 2017 Jul 10;56(29):8495-8499. doi: 10.1002/anie.201703360. Epub 2017 Jun 13.

PMID:
28513074
12.

The pharmacology of voltage-gated sodium channel activators.

Deuis JR, Mueller A, Israel MR, Vetter I.

Neuropharmacology. 2017 Dec;127:87-108. doi: 10.1016/j.neuropharm.2017.04.014. Epub 2017 Apr 14. Review.

PMID:
28416444
13.

The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant.

Rahnama S, Deuis JR, Cardoso FC, Ramanujam V, Lewis RJ, Rash LD, King GF, Vetter I, Mobli M.

PLoS One. 2017 Mar 16;12(3):e0173551. doi: 10.1371/journal.pone.0173551. eCollection 2017.

14.

Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1.

Inserra MC, Israel MR, Caldwell A, Castro J, Deuis JR, Harrington AM, Keramidas A, Garcia-Caraballo S, Maddern J, Erickson A, Grundy L, Rychkov GY, Zimmermann K, Lewis RJ, Brierley SM, Vetter I.

Sci Rep. 2017 Feb 22;7:42810. doi: 10.1038/srep42810.

15.

Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a.

Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, Christie MJ, King GF, Alewood PF, Lewis RJ, Wood JN, Vetter I.

Sci Rep. 2017 Jan 20;7:40883. doi: 10.1038/srep40883. Erratum in: Sci Rep. 2017 May 26;7:46816.

16.

Role of the NLRP3 inflammasome in a model of acute burn-induced pain.

Deuis JR, Yin K, Cooper MA, Schroder K, Vetter I.

Burns. 2017 Mar;43(2):304-309. doi: 10.1016/j.burns.2016.09.001. Epub 2016 Dec 28.

PMID:
28040362
17.

NaV1.7 as a pain target - From gene to pharmacology.

Vetter I, Deuis JR, Mueller A, Israel MR, Starobova H, Zhang A, Rash LD, Mobli M.

Pharmacol Ther. 2017 Apr;172:73-100. doi: 10.1016/j.pharmthera.2016.11.015. Epub 2016 Dec 2. Review. No abstract available.

PMID:
27916648
18.

The thermal probe test: A novel behavioral assay to quantify thermal paw withdrawal thresholds in mice.

Deuis JR, Vetter I.

Temperature (Austin). 2016 Feb 26;3(2):199-207. eCollection 2016 Apr-Jun.

19.

The Snake with the Scorpion's Sting: Novel Three-Finger Toxin Sodium Channel Activators from the Venom of the Long-Glanded Blue Coral Snake (Calliophis bivirgatus).

Yang DC, Deuis JR, Dashevsky D, Dobson J, Jackson TN, Brust A, Xie B, Koludarov I, Debono J, Hendrikx I, Hodgson WC, Josh P, Nouwens A, Baillie GJ, Bruxner TJ, Alewood PF, Lim KK, Frank N, Vetter I, Fry BG.

Toxins (Basel). 2016 Oct 18;8(10). pii: E303.

20.

Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target.

Yin K, Deuis JR, Lewis RJ, Vetter I.

Mol Pain. 2016 Aug 28;12. pii: 1744806916665366. doi: 10.1177/1744806916665366. Print 2016.

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