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Items: 1 to 20 of 152


X-ray Crystallography and Unexpected Chiroptical Properties Reassign the Configuration of Haliclonadiamine.

Liu HB, Imler GH, Baldridge KK, O'Connor RD, Siegel JS, Deschamps JR, Bewley CA.

J Am Chem Soc. 2020 Feb 12;142(6):2755-2759. doi: 10.1021/jacs.9b12926. Epub 2020 Jan 30.


A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter.

Slack RD, Abramyan AM, Tang H, Meena S, Davis BA, Bonifazi A, Giancola JB, Deschamps JR, Naing S, Yano H, Singh SK, Newman AH, Shi L.

ACS Chem Neurosci. 2019 Sep 18;10(9):3946-3952. doi: 10.1021/acschemneuro.9b00375. Epub 2019 Aug 22.


Conformational Details of Quantum Dot-DNA Resolved by Förster Resonance Energy Transfer Lifetime Nanoruler.

Guo J, Qiu X, Mingoes C, Deschamps JR, Susumu K, Medintz IL, Hildebrandt N.

ACS Nano. 2019 Jan 22;13(1):505-514. doi: 10.1021/acsnano.8b07137. Epub 2018 Dec 6.


B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation.

Garai S, Raja KS, Papke RL, Deschamps JR, Damaj MI, Thakur GA.

ACS Med Chem Lett. 2018 Oct 11;9(11):1144-1148. doi: 10.1021/acsmedchemlett.8b00407. eCollection 2018 Nov 8.


Synthesis and Characterization of the Selective, Reversible PKCβ Inhibitor (9 S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9 H,18 H-5,21:12,17-dimethenodibenzo[ e,k]pyrrolo[3,4- h][1,4,13]oxadiazacyclohexadecine-18,20(19 H)-dione, Ruboxistaurin (LY333531).

Lewin AH, Brieaddy L, Deschamps JR, Imler GH, Mascarella SW, Reddy PA, Carroll FI.

ACS Chem Neurosci. 2019 Jan 16;10(1):246-251. doi: 10.1021/acschemneuro.8b00196. Epub 2018 Sep 11.


Two CuII complexes of 3,4,5-tri-methyl-1H-pyrazole.

Vincent CJ, Giles ID, Deschamps JR.

Acta Crystallogr E Crystallogr Commun. 2018 Feb 16;74(Pt 3):357-362. doi: 10.1107/S2056989018002359. eCollection 2018 Mar 1.


A High Aspect Ratio Bifurcated 128-Microchannel Microfluidic Device for Environmental Monitoring of Explosives.

Charles PT, Wadhwa V, Kouyate A, Mesa-Donado KJ, Adams AA, Deschamps JR, Kusterbeck AW.

Sensors (Basel). 2018 May 15;18(5). pii: E1568. doi: 10.3390/s18051568.


Synthesis and Structural Elucidation of a Pyranomorphinan Opioid and in Vitro Studies.

Ansari MI, Healy JR, Hom K, Deschamps JR, Matsumoto RR, Coop A.

Org Lett. 2018 May 18;20(10):2984-2987. doi: 10.1021/acs.orglett.8b01025. Epub 2018 May 8.


Reaction Kinetics Direct a Rational Synthesis of an HIV-1 Inactivator of Nucleocapsid Protein 7 and Provide Mechanistic Insight into Cellular Metabolism and Antiviral Activity.

Nikolayevskiy H, Scerba MT, Deschamps JR, Appella DH.

Chemistry. 2018 Jul 5;24(38):9485-9489. doi: 10.1002/chem.201801253. Epub 2018 May 25.


Engineering Immunological Tolerance Using Quantum Dots to Tune the Density of Self-Antigen Display.

Hess KL, Oh E, Tostanoski LH, Andorko JI, Susumu K, Deschamps JR, Medintz IL, Jewell CM.

Adv Funct Mater. 2017 Jun 13;27(22). pii: 1700290. doi: 10.1002/adfm.201700290. Epub 2017 Apr 3.


Total Synthesis of Sarpagine-Related Bioactive Indole Alkaloids.

Rahman MT, Deschamps JR, Imler GH, Cook JM.

Chemistry. 2018 Feb 16;24(10):2354-2359. doi: 10.1002/chem.201705575. Epub 2018 Jan 23.


A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the Effects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of Abuse.

Sulima A, Jalah R, Antoline JFG, Torres OB, Imler GH, Deschamps JR, Beck Z, Alving CR, Jacobson AE, Rice KC, Matyas GR.

J Med Chem. 2018 Jan 11;61(1):329-343. doi: 10.1021/acs.jmedchem.7b01427. Epub 2017 Dec 29.


Concise Total Synthesis of (-)-Affinisine Oxindole, (+)-Isoalstonisine, (+)-Alstofoline, (-)-Macrogentine, (+)-Na -Demethylalstonisine, (-)-Alstonoxine A, and (+)-Alstonisine.

Stephen MR, Rahman MT, Tiruveedhula VVNPB, Fonseca GO, Deschamps JR, Cook JM.

Chemistry. 2017 Nov 7;23(62):15805-15819. doi: 10.1002/chem.201703572. Epub 2017 Oct 18.


Crystal structures of the three closely related compounds: bis-[(1H-tetra-zol-5-yl)meth-yl]nitramide, tri-amino-guanidinium 5-({[(1H-tetra-zol-5-yl)meth-yl](nitro)-amino}-meth-yl)tetra-zol-1-ide, and di-ammonium bis-[(tetra-zol-1-id-5-yl)meth-yl]nitramide monohydrate.

Mitchell LA, Imler GH, Parrish DA, Deschamps JR, Leonard PW, Chavez DE.

Acta Crystallogr E Crystallogr Commun. 2017 Jun 20;73(Pt 7):1056-1061. doi: 10.1107/S2056989017008817. eCollection 2017 Jul 1.


Nanoparticle cellular uptake by dendritic wedge peptides: achieving single peptide facilitated delivery.

Breger JC, Muttenthaler M, Delehanty JB, Thompson DA, Oh E, Susumu K, Deschamps JR, Anderson GP, Field LD, Walper SA, Dawson PE, Medintz IL.

Nanoscale. 2017 Jul 27;9(29):10447-10464. doi: 10.1039/c7nr03362a.


Elucidating Surface Ligand-Dependent Kinetic Enhancement of Proteolytic Activity at Surface-Modified Quantum Dots.

Díaz SA, Sen S, Boeneman Gemmill K, Brown CW 3rd, Oh E, Susumu K, Stewart MH, Breger JC, Lasarte Aragonés G, Field LD, Deschamps JR, Král P, Medintz IL.

ACS Nano. 2017 Jun 27;11(6):5884-5896. doi: 10.1021/acsnano.7b01624. Epub 2017 Jun 12.


Quantum Dot-Peptide-Fullerene Bioconjugates for Visualization of in Vitro and in Vivo Cellular Membrane Potential.

Nag OK, Stewart MH, Deschamps JR, Susumu K, Oh E, Tsytsarev V, Tang Q, Efros AL, Vaxenburg R, Black BJ, Chen Y, O'Shaughnessy TJ, North SH, Field LD, Dawson PE, Pancrazio JJ, Medintz IL, Chen Y, Erzurumlu RS, Huston AL, Delehanty JB.

ACS Nano. 2017 Jun 27;11(6):5598-5613. doi: 10.1021/acsnano.7b00954. Epub 2017 May 30.


One-pot sequential reaction to 2-substituted-phenanthridinones from N-methoxybenzamides.

Liang D, Sersen D, Yang C, Deschamps JR, Imler GH, Jiang C, Xue F.

Org Biomol Chem. 2017 May 23;15(20):4390-4398. doi: 10.1039/c7ob00649g.


Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study.

Truong PM, Hassan SA, Lee YS, Kopajtic TA, Katz JL, Chadderdon AM, Traynor JR, Deschamps JR, Jacobson AE, Rice KC.

Bioorg Med Chem. 2017 Apr 15;25(8):2406-2422. doi: 10.1016/j.bmc.2017.02.064. Epub 2017 Mar 1.


Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation.

Liang D, Yu W, Nguyen N, Deschamps JR, Imler GH, Li Y, MacKerell AD Jr, Jiang C, Xue F.

J Org Chem. 2017 Apr 7;82(7):3589-3596. doi: 10.1021/acs.joc.7b00106. Epub 2017 Mar 10.


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