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Items: 1 to 20 of 67

1.

mRNA as a Transformative Technology for Vaccine Development to Control Infectious Diseases.

Maruggi G, Zhang C, Li J, Ulmer JB, Yu D.

Mol Ther. 2019 Apr 10;27(4):757-772. doi: 10.1016/j.ymthe.2019.01.020. Epub 2019 Feb 7. Review.

PMID:
30803823
2.

Self-Amplifying RNA Vaccines for Venezuelan Equine Encephalitis Virus Induce Robust Protective Immunogenicity in Mice.

Samsa MM, Dupuy LC, Beard CW, Six CM, Schmaljohn CS, Mason PW, Geall AJ, Ulmer JB, Yu D.

Mol Ther. 2019 Apr 10;27(4):850-865. doi: 10.1016/j.ymthe.2018.12.013. Epub 2019 Jan 7.

PMID:
30770173
3.

Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection.

Baeza Garcia A, Siu E, Sun T, Exler V, Brito L, Hekele A, Otten G, Augustijn K, Janse CJ, Ulmer JB, Bernhagen J, Fikrig E, Geall A, Bucala R.

Nat Commun. 2018 Jul 13;9(1):2714. doi: 10.1038/s41467-018-05041-7.

4.

Generation and characterization of a bivalent protein boost for future clinical trials: HIV-1 subtypes CR01_AE and B gp120 antigens with a potent adjuvant.

Wen Y, Trinh HV, Linton CE, Tani C, Norais N, Martinez-Guzman D, Ramesh P, Sun Y, Situ F, Karaca-Griffin S, Hamlin C, Onkar S, Tian S, Hilt S, Malyala P, Lodaya R, Li N, Otten G, Palladino G, Friedrich K, Aggarwal Y, LaBranche C, Duffy R, Shen X, Tomaras GD, Montefiori DC, Fulp W, Gottardo R, Burke B, Ulmer JB, Zolla-Pazner S, Liao HX, Haynes BF, Michael NL, Kim JH, Rao M, O'Connell RJ, Carfi A, Barnett SW.

PLoS One. 2018 Apr 26;13(4):e0194266. doi: 10.1371/journal.pone.0194266. eCollection 2018.

5.

Mechanism of action of mRNA-based vaccines.

Iavarone C, O'hagan DT, Yu D, Delahaye NF, Ulmer JB.

Expert Rev Vaccines. 2017 Sep;16(9):871-881. doi: 10.1080/14760584.2017.1355245. Epub 2017 Jul 28. Review.

PMID:
28701102
6.

Induction of an IFN-Mediated Antiviral Response by a Self-Amplifying RNA Vaccine: Implications for Vaccine Design.

Pepini T, Pulichino AM, Carsillo T, Carlson AL, Sari-Sarraf F, Ramsauer K, Debasitis JC, Maruggi G, Otten GR, Geall AJ, Yu D, Ulmer JB, Iavarone C.

J Immunol. 2017 May 15;198(10):4012-4024. doi: 10.4049/jimmunol.1601877. Epub 2017 Apr 17.

7.

Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge.

Magini D, Giovani C, Mangiavacchi S, Maccari S, Cecchi R, Ulmer JB, De Gregorio E, Geall AJ, Brazzoli M, Bertholet S.

PLoS One. 2016 Aug 15;11(8):e0161193. doi: 10.1371/journal.pone.0161193. eCollection 2016.

8.

Recent innovations in mRNA vaccines.

Ulmer JB, Geall AJ.

Curr Opin Immunol. 2016 Aug;41:18-22. doi: 10.1016/j.coi.2016.05.008. Epub 2016 May 26. Review.

PMID:
27240054
9.

Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin.

Brazzoli M, Magini D, Bonci A, Buccato S, Giovani C, Kratzer R, Zurli V, Mangiavacchi S, Casini D, Brito LM, De Gregorio E, Mason PW, Ulmer JB, Geall AJ, Bertholet S.

J Virol. 2015 Oct 14;90(1):332-44. doi: 10.1128/JVI.01786-15. Print 2016 Jan 1.

10.

Self-amplifying mRNA vaccines.

Brito LA, Kommareddy S, Maione D, Uematsu Y, Giovani C, Berlanda Scorza F, Otten GR, Yu D, Mandl CW, Mason PW, Dormitzer PR, Ulmer JB, Geall AJ.

Adv Genet. 2015;89:179-233. doi: 10.1016/bs.adgen.2014.10.005. Epub 2014 Dec 4.

PMID:
25620012
11.

Vaccines 'on demand': science fiction or a future reality.

Ulmer JB, Mansoura MK, Geall AJ.

Expert Opin Drug Discov. 2015 Feb;10(2):101-6. doi: 10.1517/17460441.2015.996128. Epub 2015 Jan 13.

PMID:
25582273
12.

Introduction to RNA-based vaccines and therapeutics.

Geall AJ, Ulmer JB.

Expert Rev Vaccines. 2015 Feb;14(2):151-2. doi: 10.1586/14760584.2015.1001244. Epub 2015 Jan 12. No abstract available.

PMID:
25578187
13.

Potent immune responses in rhesus macaques induced by nonviral delivery of a self-amplifying RNA vaccine expressing HIV type 1 envelope with a cationic nanoemulsion.

Bogers WM, Oostermeijer H, Mooij P, Koopman G, Verschoor EJ, Davis D, Ulmer JB, Brito LA, Cu Y, Banerjee K, Otten GR, Burke B, Dey A, Heeney JL, Shen X, Tomaras GD, Labranche C, Montefiori DC, Liao HX, Haynes B, Geall AJ, Barnett SW.

J Infect Dis. 2015 Mar 15;211(6):947-55. doi: 10.1093/infdis/jiu522. Epub 2014 Sep 18.

14.

A cationic nanoemulsion for the delivery of next-generation RNA vaccines.

Brito LA, Chan M, Shaw CA, Hekele A, Carsillo T, Schaefer M, Archer J, Seubert A, Otten GR, Beard CW, Dey AK, Lilja A, Valiante NM, Mason PW, Mandl CW, Barnett SW, Dormitzer PR, Ulmer JB, Singh M, O'Hagan DT, Geall AJ.

Mol Ther. 2014 Dec;22(12):2118-29. doi: 10.1038/mt.2014.133. Epub 2014 Jul 16.

15.

Nucleic acid vaccines: prospects for non-viral delivery of mRNA vaccines.

Deering RP, Kommareddy S, Ulmer JB, Brito LA, Geall AJ.

Expert Opin Drug Deliv. 2014 Jun;11(6):885-99. doi: 10.1517/17425247.2014.901308. Epub 2014 Mar 26. Review.

PMID:
24665982
16.

Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regimen elicits T cell and neutralizing antibody immune responses.

Chmielewska AM, Naddeo M, Capone S, Ammendola V, Hu K, Meredith L, Verhoye L, Rychlowska M, Rappuoli R, Ulmer JB, Colloca S, Nicosia A, Cortese R, Leroux-Roels G, Balfe P, Bienkowska-Szewczyk K, Meuleman P, McKeating JA, Folgori A.

J Virol. 2014 May;88(10):5502-10. doi: 10.1128/JVI.03574-13. Epub 2014 Mar 5.

17.

Vaccine adjuvants: mode of action.

De Gregorio E, Caproni E, Ulmer JB.

Front Immunol. 2013 Jul 31;4:214. doi: 10.3389/fimmu.2013.00214. eCollection 2013.

18.

Rapidly produced SAM(®) vaccine against H7N9 influenza is immunogenic in mice.

Hekele A, Bertholet S, Archer J, Gibson DG, Palladino G, Brito LA, Otten GR, Brazzoli M, Buccato S, Bonci A, Casini D, Maione D, Qi ZQ, Gill JE, Caiazza NC, Urano J, Hubby B, Gao GF, Shu Y, De Gregorio E, Mandl CW, Mason PW, Settembre EC, Ulmer JB, Craig Venter J, Dormitzer PR, Rappuoli R, Geall AJ.

Emerg Microbes Infect. 2013 Aug;2(8):e52. doi: 10.1038/emi.2013.54. Epub 2013 Aug 14.

19.

RNA: the new revolution in nucleic acid vaccines.

Geall AJ, Mandl CW, Ulmer JB.

Semin Immunol. 2013 Apr;25(2):152-9. doi: 10.1016/j.smim.2013.05.001. Epub 2013 Jun 2. Review.

PMID:
23735226
20.

Therapeutic vaccines and immunotherapies: current challenges and new frontiers.

Oviedo-Orta E, Plotkin SA, Ulmer JB, Ahmed SS.

Expert Rev Vaccines. 2013 Mar;12(3):243-4. doi: 10.1586/erv.13.29. No abstract available.

PMID:
23496662

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