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Items: 1 to 20 of 37

1.

Solid-Phase Synthesis of Substrate-Based Dipeptides and Heterocyclic Pseudo-dipeptides as Potential NO Synthase Inhibitors.

Touati-Jallabe Y, Tintillier T, Mauchauffée E, Boucher JL, Leroy J, Ramassamy B, Hamzé A, Mezghenna K, Bouzekrini A, Verna C, Martinez J, Lajoix AD, Hernandez JF.

ChemMedChem. 2020 Mar 18;15(6):517-531. doi: 10.1002/cmdc.201900659. Epub 2020 Feb 27.

PMID:
32027778
2.

The HslV Protease from Leishmania major and Its Activation by C-terminal HslU Peptides.

Kebe NM, Samanta K, Singh P, Lai-Kee-Him J, Apicella V, Payrot N, Lauraire N, Legrand B, Lisowski V, Mbang-Benet DE, Pages M, Bastien P, Kajava AV, Bron P, Hernandez JF, Coux O.

Int J Mol Sci. 2019 Feb 26;20(5). pii: E1021. doi: 10.3390/ijms20051021.

3.

Methamphetamine regulates βAPP processing in human neuroblastoma cells.

Shukla M, Maitra S, Hernandez JF, Govitrapong P, Vincent B.

Neurosci Lett. 2019 May 14;701:20-25. doi: 10.1016/j.neulet.2019.02.023. Epub 2019 Feb 13.

PMID:
30771376
4.

Calibration of 1,2,4-Triazole-3-Thione, an Original Zn-Binding Group of Metallo-β-Lactamase Inhibitors. Validation of a Polarizable MM/MD Potential by Quantum Chemistry.

Kwapien K, Damergi M, Nader S, El Khoury L, Hobaika Z, Maroun RG, Piquemal JP, Gavara L, Berthomieu D, Hernandez JF, Gresh N.

J Phys Chem B. 2017 Jul 6;121(26):6295-6312. doi: 10.1021/acs.jpcb.7b01053. Epub 2017 Jun 22.

PMID:
28574718
5.

1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases.

Sevaille L, Gavara L, Bebrone C, De Luca F, Nauton L, Achard M, Mercuri P, Tanfoni S, Borgianni L, Guyon C, Lonjon P, Turan-Zitouni G, Dzieciolowski J, Becker K, Bénard L, Condon C, Maillard L, Martinez J, Frère JM, Dideberg O, Galleni M, Docquier JD, Hernandez JF.

ChemMedChem. 2017 Jun 21;12(12):972-985. doi: 10.1002/cmdc.201700186. Epub 2017 Jun 12.

PMID:
28505394
6.

The Polyherbal Wattana Formula Displays Anti-Amyloidogenic Properties by Increasing α-Secretase Activities.

Htoo HH, Limsuvan S, Thamsermsang O, Hernandez JF, Checler F, Govitrapong P, Pakaprot N, Akarasereenont P, Vincent B.

PLoS One. 2017 Jan 20;12(1):e0170360. doi: 10.1371/journal.pone.0170360. eCollection 2017.

7.

Deglycosylated bleomycin has the antitumor activity of bleomycin without pulmonary toxicity.

Burgy O, Wettstein G, Bellaye PS, Decologne N, Racoeur C, Goirand F, Beltramo G, Hernandez JF, Kenani A, Camus P, Bettaieb A, Garrido C, Bonniaud P.

Sci Transl Med. 2016 Feb 17;8(326):326ra20. doi: 10.1126/scitranslmed.aad7785.

PMID:
26888428
8.

Structure-Activity Relationships of JMV4463, a Vectorized Cathepsin D Inhibitor with Antiproliferative Properties: The Unique Role of the AMPA-Based Vector.

Vezenkov LL, Sanchez CA, Bellet V, Martin V, Maynadier M, Bettache N, Lisowski V, Martinez J, Garcia M, Amblard M, Hernandez JF.

ChemMedChem. 2016 Feb 4;11(3):302-8. doi: 10.1002/cmdc.201500457. Epub 2015 Dec 7.

PMID:
26639308
9.

Melatonin stimulates the nonamyloidogenic processing of βAPP through the positive transcriptional regulation of ADAM10 and ADAM17.

Shukla M, Htoo HH, Wintachai P, Hernandez JF, Dubois C, Postina R, Xu H, Checler F, Smith DR, Govitrapong P, Vincent B.

J Pineal Res. 2015 Mar;58(2):151-65. doi: 10.1111/jpi.12200. Epub 2014 Dec 27.

PMID:
25491598
10.

Blood-brain transfer and antinociception of linear and cyclic N-methyl-guanidine and thiourea-enkephalins.

Verbeken M, Wynendaele E, Mauchauffée E, Bracke N, Stalmans S, Bojnik E, Benyhe S, Peremans K, Polis I, Burvenich C, Gjedde A, Hernandez JF, De Spiegeleer B.

Peptides. 2015 Jan;63:10-21. doi: 10.1016/j.peptides.2014.10.010. Epub 2014 Nov 4.

PMID:
25451468
11.

A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase.

Giganti D, Bouillon A, Tawk L, Robert F, Martinez M, Crublet E, Weber P, Girard-Blanc C, Petres S, Haouz A, Hernandez JF, Mercereau-Puijalon O, Alzari PM, Barale JC.

Nat Commun. 2014 Sep 10;5:4833. doi: 10.1038/ncomms5833.

PMID:
25204226
12.

The bacterial-like HslVU protease complex subunits are involved in the control of different cell cycle events in trypanosomatids.

Mbang-Benet DE, Sterkers Y, Morelle C, Kebe NM, Crobu L, Portalès P, Coux O, Hernandez JF, Meghamla S, Pagès M, Bastien P.

Acta Trop. 2014 Mar;131:22-31. doi: 10.1016/j.actatropica.2013.11.017. Epub 2013 Dec 1.

PMID:
24299926
13.

Dipeptide mimic oligomer transporter mediates intracellular delivery of Cathepsin D inhibitors: a potential target for cancer therapy.

Maynadier M, Vezenkov LL, Amblard M, Martin V, Gandreuil C, Vaillant O, Gary-Bobo M, Basile I, Hernandez JF, Garcia M, Martinez J.

J Control Release. 2013 Oct 28;171(2):251-7. doi: 10.1016/j.jconrel.2013.07.017. Epub 2013 Jul 27.

PMID:
23899821
14.

Cyclic enkephalins with a diversely substituted guanidine bridge or a thiourea bridge: synthesis, biological and structural evaluations.

Touati-Jallabe Y, Bojnik E, Legrand B, Mauchauffée E, Chung NN, Schiller PW, Benyhe S, Averlant-Petit MC, Martinez J, Hernandez JF.

J Med Chem. 2013 Jul 25;56(14):5964-5973. doi: 10.1021/jm4008592. Epub 2013 Jul 12.

15.

Montpellier Infectious Diseases (MID), 2nd annual meeting (2012).

Bastien P, Braun-Breton C, Chazal N, Devaux C, Foulongne V, Frank M, Hernandez JF, Kremer L, Lebrun M, Le Moing V, Leonetti JP, Lionne C, Peyrottes S.

Infect Genet Evol. 2013 Jun;16:450-4. doi: 10.1016/j.meegid.2013.01.019. Epub 2013 Feb 14.

PMID:
23416259
16.

Further characterization of a putative serine protease contributing to the γ-secretase cleavage of β-amyloid precursor protein.

Peuchmaur M, Lacour MA, Sévalle J, Lisowski V, Touati-Jallabe Y, Rodier F, Martinez J, Checler F, Hernandez JF.

Bioorg Med Chem. 2013 Feb 15;21(4):1018-29. doi: 10.1016/j.bmc.2012.11.045. Epub 2012 Dec 5.

PMID:
23294826
17.

Activation of α-secretase by curcumin-aminoacid conjugates.

Narasingappa RB, Javagal MR, Pullabhatla S, Htoo HH, Rao JK, Hernandez JF, Govitrapong P, Vincent B.

Biochem Biophys Res Commun. 2012 Aug 10;424(4):691-6. doi: 10.1016/j.bbrc.2012.07.010. Epub 2012 Jul 13. Erratum in: Biochem Biophys Res Commun. 2012 Oct 5;426(4):665. Narasingapa, Ramesh B [corrected to Narasingappa, Ramesh B]; Jargaval, Manjunatha R [corrected to Javagal, Manjunatha R].

PMID:
22796219
18.

L-arginine binding to human inducible nitric oxide synthase: an antisymmetric funnel route toward isoform-specific inhibitors?

Floquet N, Hernandez JF, Boucher JL, Martinez J.

J Chem Inf Model. 2011 Jun 27;51(6):1325-35. doi: 10.1021/ci100422v. Epub 2011 May 16.

PMID:
21574590
19.

Cyclic peptides with a diversely substituted guanidine bridge: solid-phase synthesis and structural analysis.

Touati-Jallabe Y, Chiche L, Hamzé A, Aumelas A, Lisowski V, Berthomieu D, Martinez J, Hernandez JF.

Chemistry. 2011 Feb 25;17(9):2566-70. doi: 10.1002/chem.201003299. Epub 2011 Feb 3. No abstract available.

PMID:
21294201
20.

Noncationic dipeptide mimic oligomers as cell penetrating nonpeptides (CPNP).

Vezenkov LL, Maynadier M, Hernandez JF, Averlant-Petit MC, Fabre O, Benedetti E, Garcia M, Martinez J, Amblard M.

Bioconjug Chem. 2010 Oct 20;21(10):1850-4. doi: 10.1021/bc1002086.

PMID:
20815388

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