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Items: 1 to 20 of 49

1.

Electromechanical Properties of PVDF-Based Polymers Reinforced with Nanocarbonaceous Fillers for Pressure Sensing Applications.

Vicente J, Costa P, Lanceros-Mendez S, Abete JM, Iturrospe A.

Materials (Basel). 2019 Oct 29;12(21). pii: E3545. doi: 10.3390/ma12213545.

2.

Structural and Biological Basis of Small Molecule Inhibition of Escherichia coli LpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.

Ma X, Prathapam R, Wartchow C, Chie-Leon B, Ho CM, De Vicente J, Han W, Li M, Lu Y, Ramurthy S, Shia S, Steffek M, Uehara T.

ACS Infect Dis. 2019 Aug 22. doi: 10.1021/acsinfecdis.9b00127. [Epub ahead of print]

PMID:
31402665
3.

A Chronic Ocular-Hypertensive Rat Model induced by Injection of the Sclerosant Agent Polidocanol in the Aqueous Humor Outflow Pathway.

Blanco R, Martinez-Navarrete G, Pérez-Rico C, Valiente-Soriano FJ, Avilés-Trigueros M, Vicente J, Fernandez E, Vidal-Sanz M, de la Villa P.

Int J Mol Sci. 2019 Jun 29;20(13). pii: E3209. doi: 10.3390/ijms20133209.

4.

Development of permanent magnet MnAlC/polymer composites and flexible filament for bonding and 3D-printing technologies.

Palmero EM, Rial J, de Vicente J, Camarero J, Skårman B, Vidarsson H, Larsson PO, Bollero A.

Sci Technol Adv Mater. 2018 May 30;19(1):465-473. doi: 10.1080/14686996.2018.1471321. eCollection 2018.

5.

Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity.

Skepper CK, Moreau RJ, Appleton BA, Benton BM, Drumm JE 3rd, Feng BY, Geng M, Hu C, Li C, Lingel A, Lu Y, Mamo M, Mergo W, Mostafavi M, Rath CM, Steffek M, Takeoka KT, Uehara K, Wang L, Wei JR, Xie L, Xu W, Zhang Q, de Vicente J.

J Med Chem. 2018 Apr 26;61(8):3325-3349. doi: 10.1021/acs.jmedchem.7b01861. Epub 2018 Apr 13.

PMID:
29551072
6.

Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria.

Moreau RJ, Skepper CK, Appleton BA, Blechschmidt A, Balibar CJ, Benton BM, Drumm JE 3rd, Feng BY, Geng M, Li C, Lindvall MK, Lingel A, Lu Y, Mamo M, Mergo W, Polyakov V, Smith TM, Takeoka K, Uehara K, Wang L, Wei JR, Weiss AH, Xie L, Xu W, Zhang Q, de Vicente J.

J Med Chem. 2018 Apr 26;61(8):3309-3324. doi: 10.1021/acs.jmedchem.7b01691. Epub 2018 Apr 9.

PMID:
29498517
7.

Optimization of CoaD Inhibitors against Gram-Negative Organisms through Targeted Metabolomics.

Rath CM, Benton BM, de Vicente J, Drumm JE, Geng M, Li C, Moreau RJ, Shen X, Skepper CK, Steffek M, Takeoka K, Wang L, Wei JR, Xu W, Zhang Q, Feng BY.

ACS Infect Dis. 2018 Mar 9;4(3):391-402. doi: 10.1021/acsinfecdis.7b00214. Epub 2017 Dec 22.

PMID:
29243909
8.

Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors.

de Vicente J, Tivitmahaisoon P, Berry P, Bolin DR, Carvajal D, He W, Huang KS, Janson C, Liang L, Lukacs C, Petersen A, Qian H, Yi L, Zhuang Y, Hermann JC.

ACS Med Chem Lett. 2015 Aug 4;6(9):1019-24. doi: 10.1021/acsmedchemlett.5b00251. eCollection 2015 Sep 10.

9.

Knowledge-Based Personal Health System to empower outpatients of diabetes mellitus by means of P4 Medicine.

Bresó A, Sáez C, Vicente J, Larrinaga F, Robles M, García-Gómez JM.

Methods Mol Biol. 2015;1246:237-57. doi: 10.1007/978-1-4939-1985-7_15.

PMID:
25417090
10.

Audit method suited for DSS in clinical environment.

Vicente J.

Methods Mol Biol. 2015;1246:39-56. doi: 10.1007/978-1-4939-1985-7_3.

PMID:
25417078
11.

Scaffold hopping towards potent and selective JAK3 inhibitors: discovery of novel C-5 substituted pyrrolopyrazines.

de Vicente J, Lemoine R, Bartlett M, Hermann JC, Hekmat-Nejad M, Henningsen R, Jin S, Kuglstatter A, Li H, Lovey AJ, Menke J, Niu L, Patel V, Petersen A, Setti L, Shao A, Tivitmahaisoon P, Vu MD, Soth M.

Bioorg Med Chem Lett. 2014 Nov 1;24(21):4969-75. doi: 10.1016/j.bmcl.2014.09.031. Epub 2014 Sep 21.

PMID:
25262541
12.

Analysis of mobile health applications for a broad spectrum of consumers: a user experience approach.

García-Gómez JM, de la Torre-Díez I, Vicente J, Robles M, López-Coronado M, Rodrigues JJ.

Health Informatics J. 2014 Mar;20(1):74-84. doi: 10.1177/1460458213479598.

PMID:
24550566
13.

Discovery of N-[4-[6-tert-butyl-5-methoxy-8-(6-methoxy-2-oxo-1H-pyridin-3-yl)-3-quinolyl]phenyl]methanesulfonamide (RG7109), a potent inhibitor of the hepatitis C virus NS5B polymerase.

Talamas FX, Abbot SC, Anand S, Brameld KA, Carter DS, Chen J, Davis D, de Vicente J, Fung AD, Gong L, Harris SF, Inbar P, Labadie SS, Lee EK, Lemoine R, Le Pogam S, Leveque V, Li J, McIntosh J, Nájera I, Park J, Railkar A, Rajyaguru S, Sangi M, Schoenfeld RC, Staben LR, Tan Y, Taygerly JP, Villaseñor AG, Weller PE.

J Med Chem. 2014 Mar 13;57(5):1914-31. doi: 10.1021/jm401329s. Epub 2013 Nov 6.

14.

Discovery of a novel series of potent non-nucleoside inhibitors of hepatitis C virus NS5B.

Schoenfeld RC, Bourdet DL, Brameld KA, Chin E, de Vicente J, Fung A, Harris SF, Lee EK, Le Pogam S, Leveque V, Li J, Lui AS, Najera I, Rajyaguru S, Sangi M, Steiner S, Talamas FX, Taygerly JP, Zhao J.

J Med Chem. 2013 Oct 24;56(20):8163-82. doi: 10.1021/jm401266k. Epub 2013 Oct 10.

15.

Bronchogenic cyst in adult siblings.

Ramírez-Camacho R, Trinidad A, Vicente J, Salas I, Roldán A, Casares C.

J Otolaryngol Head Neck Surg. 2012 Dec;41(6):E51-3. No abstract available.

PMID:
23700591
16.

Familial dermatofibrosarcoma protuberans: a nonfortuitous association?

Marre D, Redondo P, Vicente J.

Dermatol Surg. 2013 May;39(5):820-1. doi: 10.1111/dsu.12187. No abstract available.

PMID:
23627813
17.

Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors.

Jaime-Figueroa S, De Vicente J, Hermann J, Jahangir A, Jin S, Kuglstatter A, Lynch SM, Menke J, Niu L, Patel V, Shao A, Soth M, Vu MD, Yee C.

Bioorg Med Chem Lett. 2013 May 1;23(9):2522-6. doi: 10.1016/j.bmcl.2013.03.015. Epub 2013 Mar 14.

PMID:
23541670
18.

De novo fragment design: a medicinal chemistry approach to fragment-based lead generation.

Talamas FX, Ao-Ieong G, Brameld KA, Chin E, de Vicente J, Dunn JP, Ghate M, Giannetti AM, Harris SF, Labadie SS, Leveque V, Li J, Lui AS, McCaleb KL, Nájera I, Schoenfeld RC, Wang B, Wong A.

J Med Chem. 2013 Apr 11;56(7):3115-9. doi: 10.1021/jm4002605. Epub 2013 Mar 29.

PMID:
23509929
19.

Extracting MRS discriminant functional features of brain tumors.

Fuster-Garcia E, Tortajada S, Vicente J, Robles M, García-Gómez JM.

NMR Biomed. 2013 May;26(5):578-92. doi: 10.1002/nbm.2895. Epub 2012 Dec 12.

PMID:
23239454
20.

An HL7-CDA wrapper for facilitating semantic interoperability to rule-based Clinical Decision Support Systems.

Sáez C, Bresó A, Vicente J, Robles M, García-Gómez JM.

Comput Methods Programs Biomed. 2013 Mar;109(3):239-49. doi: 10.1016/j.cmpb.2012.10.003. Epub 2012 Nov 27.

PMID:
23199936

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