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Items: 1 to 20 of 71

1.

Optimization of a 1,3,4-oxadiazole series for inhibition of Ca2+/calmodulin-stimulated activity of adenylyl cyclases 1 and 8 for the treatment of chronic pain.

Kaur J, Soto-Velasquez M, Ding Z, Ghanbarpour A, Lill MA, van Rijn RM, Watts VJ, Flaherty DP.

Eur J Med Chem. 2019 Jan 15;162:568-585. doi: 10.1016/j.ejmech.2018.11.036. Epub 2018 Nov 16.

PMID:
30472604
2.

Glutathione S-Transferase π-Activatable O2-(Sulfonylethyl Derived) Diazeniumdiolates Potently Suppress Melanoma in Vitro and in Vivo.

Huang Z, Wu J, Zou Y, Yuan H, Zhang Y, Fei Y, Bhardwaj A, Kaur J, Knaus EE, Zhang Y.

J Med Chem. 2018 Mar 8;61(5):1833-1844. doi: 10.1021/acs.jmedchem.7b01178. Epub 2018 Feb 16.

PMID:
29420887
3.

In situ click chemistry generation of cyclooxygenase-2 inhibitors.

Bhardwaj A, Kaur J, Wuest M, Wuest F.

Nat Commun. 2017 Feb 23;8(1):1. doi: 10.1038/s41467-016-0009-6.

4.

Fluorescent Hexose Conjugates Establish Stringent Stereochemical Requirement by GLUT5 for Recognition and Transport of Monosaccharides.

Soueidan OM, Scully TW, Kaur J, Panigrahi R, Belovodskiy A, Do V, Matier CD, Lemieux MJ, Wuest F, Cheeseman C, West FG.

ACS Chem Biol. 2017 Apr 21;12(4):1087-1094. doi: 10.1021/acschembio.6b01101. Epub 2017 Mar 2.

PMID:
28205432
5.

Genomic and metabolic characterisation of alkaloid biosynthesis by asexual Epichloë fungal endophytes of tall fescue pasture grasses.

Ekanayake PN, Kaur J, Tian P, Rochfort SJ, Guthridge KM, Sawbridge TI, Spangenberg GC, Forster JW.

Genome. 2017 Jun;60(6):496-509. doi: 10.1139/gen-2016-0173. Epub 2017 Jan 4.

PMID:
28177829
6.

Subcellular differential expression of Ep-ICD in oral dysplasia and cancer is associated with disease progression and prognosis.

Somasundaram RT, Kaur J, Leong I, MacMillan C, Witterick IJ, Walfish PG, Ralhan R.

BMC Cancer. 2016 Jul 16;16:486. doi: 10.1186/s12885-016-2507-7.

7.

Pyrimidine-based fluorescent COX-2 inhibitors: synthesis and biological evaluation.

Tietz O, Kaur J, Bhardwaj A, Wuest FR.

Org Biomol Chem. 2016 Jul 26;14(30):7250-7. doi: 10.1039/c6ob00493h.

PMID:
27383140
8.

Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer.

Kumar M, Matta A, Masui O, Srivastava G, Kaur J, Thakar A, Shukla NK, RoyChoudhury A, Sharma M, Walfish PG, Michael Siu KW, Chauhan SS, Ralhan R.

J Transl Med. 2015 Aug 30;13:285. doi: 10.1186/s12967-015-0637-3.

9.

Design, Synthesis, and Evaluation of an (18)F-Labeled Radiotracer Based on Celecoxib-NBD for Positron Emission Tomography (PET) Imaging of Cyclooxygenase-2 (COX-2).

Kaur J, Tietz O, Bhardwaj A, Marshall A, Way J, Wuest M, Wuest F.

ChemMedChem. 2015 Oct;10(10):1635-40. doi: 10.1002/cmdc.201500287. Epub 2015 Aug 18.

PMID:
26287271
10.

Unbelievable, Yet True….Spontaneous Quintuplets!

Kaur J, Pandit SN, Gade MP.

J Obstet Gynaecol India. 2015 Jul;65(4):271-2. doi: 10.1007/s13224-014-0631-3. Epub 2014 Dec 25. No abstract available.

11.

Prognostic significance of cytoplasmic S100A2 overexpression in oral cancer patients.

Kumar M, Srivastava G, Kaur J, Assi J, Alyass A, Leong I, MacMillan C, Witterick I, Shukla NK, Thakar A, Duggal R, Roychoudhury A, Sharma MC, Walfish PG, Chauhan SS, Ralhan R.

J Transl Med. 2015 Jan 16;13:8. doi: 10.1186/s12967-014-0369-9.

12.

Do nitric oxide-releasing drugs offer a potentially new paradigm for the management of cardiovascular risks in diabetes?

Bhardwaj A, Kaur J, Wuest F, Knaus EE.

Expert Rev Cardiovasc Ther. 2014 May;12(5):533-6. doi: 10.1586/14779072.2014.897227. Epub 2014 Apr 11.

PMID:
24725228
13.

Fluorophore-labeled cyclooxygenase-2 inhibitors for the imaging of cyclooxygenase-2 overexpression in cancer: synthesis and biological studies.

Bhardwaj A, Kaur J, Wuest F, Knaus EE.

ChemMedChem. 2014 Jan;9(1):109-16, 240. doi: 10.1002/cmdc.201300355. Epub 2013 Oct 31.

PMID:
24376205
14.

Synthesis of three 18F-labelled cyclooxygenase-2 (COX-2) inhibitors based on a pyrimidine scaffold.

Tietz O, Sharma SK, Kaur J, Way J, Marshall A, Wuest M, Wuest F.

Org Biomol Chem. 2013 Dec 14;11(46):8052-64. doi: 10.1039/c3ob41935e.

PMID:
24145766
15.

S100A7 overexpression is a predictive marker for high risk of malignant transformation in oral dysplasia.

Kaur J, Matta A, Kak I, Srivastava G, Assi J, Leong I, Witterick I, Colgan TJ, Macmillan C, Siu KW, Walfish PG, Ralhan R.

Int J Cancer. 2014 Mar 15;134(6):1379-88. doi: 10.1002/ijc.28473. Epub 2013 Oct 8.

16.

Critical issues in a parturient with pre-existing neurological deficits with severe anaemia: A clinical challenge to anaesthesiologist and intensivist!

Kulshrestha A, Bajwa SK, Bajwa SS, Mathur M, Kaur J.

Int J Crit Illn Inj Sci. 2013 Apr;3(2):164-5. doi: 10.4103/2229-5151.114281. No abstract available.

17.

Clinical significance of altered expression of β-catenin and E-cadherin in oral dysplasia and cancer: potential link with ALCAM expression.

Kaur J, Sawhney M, DattaGupta S, Shukla NK, Srivastava A, Walfish PG, Ralhan R.

PLoS One. 2013 Jun 28;8(6):e67361. doi: 10.1371/journal.pone.0067361. Print 2013.

18.

1,4-Diaryl-substituted triazoles as cyclooxygenase-2 inhibitors: Synthesis, biological evaluation and molecular modeling studies.

Kaur J, Bhardwaj A, Sharma SK, Wuest F.

Bioorg Med Chem. 2013 Jul 15;21(14):4288-95. doi: 10.1016/j.bmc.2013.04.074. Epub 2013 May 7.

PMID:
23706267
19.

A diazen-1-ium-1,2-diolate analog of 7-azabenzobicyclo[2.2.1]heptane: synthesis, nitric oxide and nitroxyl release, in vitro hemodynamic, and anti-hypertensive studies.

Bhardwaj A, Huang Z, Kaur J, Yang F, Seubert JM, Knaus EE.

Bioorg Med Chem Lett. 2013 May 1;23(9):2769-74. doi: 10.1016/j.bmcl.2013.02.040. Epub 2013 Feb 22.

PMID:
23541649
20.

Can nitric oxide-releasing hybrid drugs alleviate adverse cardiovascular risks?

Bhardwaj A, Kaur J, Knaus EE.

Future Med Chem. 2013 Mar;5(4):381-3. doi: 10.4155/fmc.13.23. No abstract available.

PMID:
23495685

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